Novel approach to adherence assessment based on parent drug and metabolite pharmacokinetics: pilot study with spironolactone.

Autor: Pilkova A; Department of Clinical Pharmacology and Pharmacy, Institute of Pharmacology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Sima M; Department of Clinical Pharmacology and Pharmacy, Institute of Pharmacology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Hartinger JM; Department of Clinical Pharmacology and Pharmacy, Institute of Pharmacology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Nikrynova Nguyen TMP; Third Internal Department of Endocrinology and Metabolism, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Maresova V; Institute of Forensic Medicine and Toxicology, Toxicology Laboratory, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Kurcova I; Institute of Forensic Medicine and Toxicology, Toxicology Laboratory, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Slanar O; Department of Clinical Pharmacology and Pharmacy, Institute of Pharmacology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Widimsky J; Third Internal Department of Endocrinology and Metabolism, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.

Publikováno v: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia [Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub] 2024 Jun; Vol. 168 (2), pp. 117-123. Date of Electronic Publication: 2022 Dec 02.

Thermoreversible Gel Formulation for the Intranasal Delivery of Salmon Calcitonin and Comparison Studies of In Vivo Bioavailability.

Autor: ALPARSLAN, Abdullah Levent¹ elaapharm@gmail.com, YILDIZ TÜRKYILMAZ, Gülbeyaz², KOZACI, Leyla Didem³, KARASULU, Ercüment²

Publikováno v: Turkish Journal of Pharmaceutical Sciences. Jun2023, Vol. 20 Issue 3, p127-140. 14p.

Can nasal drug delivery bypass the blood-brain barrier?: questioning the direct transport theory.

Autor: Merkus FW; Leiden/Amsterdam Centre for Drug Research, Leiden University, Leiden, The Netherlands. F.Merkus@lacdr.leidenuniv.nl, van den Berg MP

Publikováno v: Drugs in R&D [Drugs R D] 2007; Vol. 8 (3), pp. 133-44.

Copolymerized Polymers Based on Cyclodextrins and Cationic Groups Enhance Therapeutic Effect of Rebamipide in the N-Acetylcysteine-Treated Dry Eye Model.

Autor: Otake, Hiroko, Kobayashi, Ko, Kadowaki, Reita, Kosaka, Taiyo, Itahashi, Mizuki, Tsubaki, Masanobu, Matsuda, Masaru, Iwakiri, Norio, Harata, Eiji, Nagai, Noriaki

Publikováno v: Drug Design, Development & Therapy; Sep2024, Vol. 18, p4345-4358, 14p

Uptake of estradiol or progesterone into the CSF following intranasal and intravenous delivery in rats.

Autor: van den Berg MP; Department of Pharmaceutical Technology and Biopharmaceutics, Leiden/Amsterdam Centre for Drug Research, Leiden University, Leiden, The Netherlands., Verhoef JC, Romeijn SG, Merkus FW

Publikováno v: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2004 Jul; Vol. 58 (1), pp. 131-5.