Network integration and modelling of dynamic drug responses at multi-omics levels.

Autor: Selevsek N; Functional Genomics Center, ETH Zurich, Switzerland., Caiment F; Department of Toxicogenomics, Maastricht University, Maastricht, The Netherlands., Nudischer R; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Gmuender H; Genedata AG, Basel, Switzerland., Agarkova I; Insphero AG, Schlieren, Switzerland., Atkinson FL; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Bachmann I; MicroDiscovery GmbH, Berlin, Germany., Baier V; Institute of Applied Microbiology, RWTH, Aachen, Germany., Barel G; Department of Computational Molecular Biology, Max-Planck-Institute for Molecular Genetics, Berlin, Germany., Bauer C; MicroDiscovery GmbH, Berlin, Germany., Boerno S; Max-Planck-Institute for Molecular Genetics, Sequencing Unit, Berlin, Germany., Bosc N; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Clayton O; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Cordes H; Institute of Applied Microbiology, RWTH, Aachen, Germany., Deeb S; Genedata AG, Basel, Switzerland., Gotta S; Genedata AG, Basel, Switzerland., Guye P; Insphero AG, Schlieren, Switzerland., Hersey A; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Hunter FMI; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Kunz L; Functional Genomics Center, ETH Zurich, Switzerland., Lewalle A; Department of Biomedical Engineering, King's College London, London, UK., Lienhard M; Department of Computational Molecular Biology, Max-Planck-Institute for Molecular Genetics, Berlin, Germany., Merken J; CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands., Minguet J; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Oliveira B; Department of Biomedical Engineering, King's College London, London, UK., Pluess C; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Sarkans U; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Schrooders Y; Department of Toxicogenomics, Maastricht University, Maastricht, The Netherlands., Schuchhardt J; MicroDiscovery GmbH, Berlin, Germany., Smit I; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Thiel C; Institute of Applied Microbiology, RWTH, Aachen, Germany., Timmermann B; Max-Planck-Institute for Molecular Genetics, Sequencing Unit, Berlin, Germany., Verheijen M; Department of Toxicogenomics, Maastricht University, Maastricht, The Netherlands., Wittenberger T; Genedata AG, Basel, Switzerland., Wolski W; Functional Genomics Center, ETH Zurich, Switzerland., Zerck A; MicroDiscovery GmbH, Berlin, Germany., Heymans S; CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands., Kuepfer L; Institute of Applied Microbiology, RWTH, Aachen, Germany., Roth A; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Schlapbach R; Functional Genomics Center, ETH Zurich, Switzerland., Niederer S; Department of Biomedical Engineering, King's College London, London, UK., Herwig R; Department of Computational Molecular Biology, Max-Planck-Institute for Molecular Genetics, Berlin, Germany. herwig@molgen.mpg.de., Kleinjans J; Department of Toxicogenomics, Maastricht University, Maastricht, The Netherlands.

Publikováno v: Communications biology [Commun Biol] 2020 Oct 15; Vol. 3 (1), pp. 573. Date of Electronic Publication: 2020 Oct 15.

Integrated analysis of single-cell RNA sequencing and bulk RNA data reveals gene regulatory networks and targets in dilated cardiomyopathy.

Autor: Zhang, Min¹ (AUTHOR), Zhang, Xin² (AUTHOR), Niu, Jiayin³ (AUTHOR), Hua, Cuncun³ (AUTHOR), Liu, Pengfei³ (AUTHOR), Zhong, Guangzhen^1,3 (AUTHOR) zhongguangzhen@bjcyh.com

Publikováno v: Scientific Reports. 6/17/2024, Vol. 14 Issue 1, p1-11. 11p.

Immunosuppressive Therapy Improves Both Short- and Long-Term Prognosis in Patients With Virus-Negative Nonfulminant Inflammatory Cardiomyopathy.

Autor: Merken J; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria. jort.merken@mumc.nl., Hazebroek M; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Van Paassen P; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Verdonschot J; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Van Empel V; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Knackstedt C; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Abdul Hamid M; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Seiler M; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Kolb J; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Hoermann P; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Ensinger C; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Brunner-La Rocca HP; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Poelzl G; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria., Heymans S; From the Cardiology Department (J.M., M.H., J.V., V.V.E., C.K., H.-P.B.-L.R., S.H.), Immunology Department (P.V.P.), and Pathology Department (M.A.H.), Maastricht University Medical Center, The Netherlands; and Clinical Division of Cardiology and Angiology (M.S., J.K., P.H., G.P.) and Institute of Pathology (C.E.), Innsbruck Medical University, Austria.

Publikováno v: Circulation. Heart failure [Circ Heart Fail] 2018 Feb; Vol. 11 (2), pp. e004228.

CMR Predictors of Favorable Outcome in Myocarditis: A Single-Center Experience.

Autor: Baritussio, Anna¹ (AUTHOR) anna.baritussio@aopd.veneto.it, Cheng, Chun-Yan¹ (AUTHOR) renzo.marcolongo@tiscali.it, Simeti, Giuseppe¹ (AUTHOR), Ocagli, Honoria² (AUTHOR), Lorenzoni, Giulia² (AUTHOR), Giordani, Andrea Silvio¹ (AUTHOR), Basso, Cristina³ (AUTHOR), Rizzo, Stefania³ (AUTHOR), De Gaspari, Monica³ (AUTHOR), Motta, Raffaella⁴ (AUTHOR), De Conti, Giorgio⁴ (AUTHOR), Perazzolo Marra, Martina¹ (AUTHOR), Tarantini, Giuseppe¹ (AUTHOR), Iliceto, Sabino¹ (AUTHOR), Gregori, Dario² (AUTHOR), Marcolongo, Renzo¹ (AUTHOR), Caforio, Alida Linda Patrizia¹ (AUTHOR) alida.caforio@unipd.it

Publikováno v: Journal of Clinical Medicine. Mar2024, Vol. 13 Issue 5, p1229. 14p.

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