Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Merja Nurkkala-Karlsson"'
Autor:
Merja Nurkkala-Karlsson, Marie K. Lagerquist, Priti Gupta, Claes Ohlsson, Dan Mellström, Cecilia Engdahl
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The link between antibodies and bone mass is debated. Activated IgG, which interacts directly with Fc gamma receptors, stimulates osteoclastogenesis in vitro, and local injection in immune-activated mice leads to bone loss. Multiple myeloma
Externí odkaz:
https://doaj.org/article/5a465448648e403aae87c800e84d95b3
Autor:
Lisa U Magnusson, Annika Lundqvist, Merja Nurkkala Karlsson, Kristina Skålén, Max Levin, Olov Wiklund, Jan Borén, Lillemor Mattsson Hultén
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43142 (2012)
Inflammation in the vascular wall is important for development of atherosclerosis. We have shown previously that arachidonate 15-lipoxygenase type B (ALOX15B) is more highly expressed in human atherosclerotic lesions than in healthy arteries. This en
Externí odkaz:
https://doaj.org/article/22e10b26dc284395a89eeeca6e8a5ad2
Autor:
Claes Ohlsson, Annica Andersson, Angelina I. Bernardi, Hans Carlsten, Louise Grahnemo, Ulrika Islander, Alexandra Stubelius, Merja Nurkkala-Karlsson
Publikováno v:
Endocrinology. 157:1013-1020
In addition to the systemic inflammation present in rheumatoid arthritis (RA), decreased estradiol levels in postmenopausal RA patients further accelerate bone loss in these patients. The tissue-selective estrogen complex (TSEC), an estrogen combined
Autor:
Merja Nurkkala-Karlsson, Angelina I. Bernardi, Claes Ohlsson, Louise Grahnemo, Hans Carlsten, Ulrika Islander, Annica Andersson
Publikováno v:
Immunity, Inflammation and Disease. 2:214-225
The third generation selective estrogen receptor modulators lasofoxifene (las) and bazedoxifene (bza) are indicated for treatment of postmenopausal osteoporosis. 17β-Estradiol (E2) and the second generation SERM raloxifene (ral) have major effects o
Autor:
C. Wasen, Mikael Brisslert, Merja Nurkkala-Karlsson, Karin M. E. Andersson, Maria Bokarewa, Malin C. Erlandsson, Ing-Marie Jonsson, Mattias Svensson, Mats Bemark
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(48)
Switched antibody classes are important for efficient immune responses. Aberrant antibody production to otherwise harmless antigens may result in autoimmunity. The protein kinase fms-like tyrosine kinase 3 receptor (Flt3) has an important role during
Autor:
Annica Andersson, Alexandra Stubelius, Hans Carlsten, Ulrika Islander, Angelina I. Bernardi, Claes Ohlsson, Merja Nurkkala-Karlsson
Publikováno v:
Rheumatology (Oxford, England)
Objective. RA predominantly affects post-menopausal women and is strongly associated with development of generalised osteoporosis. To find treatments that target both joint manifestations and osteoporosis in RA is desirable. The third generation of s
Autor:
Angelina I, Bernardi, Annica, Andersson, Louise, Grahnemo, Merja, Nurkkala-Karlsson, Claes, Ohlsson, Hans, Carlsten, Ulrika, Islander
Publikováno v:
Immunity, Inflammation and Disease
The third generation selective estrogen receptor modulators lasofoxifene (las) and bazedoxifene (bza) are indicated for treatment of postmenopausal osteoporosis. 17β-Estradiol (E2) and the second generation SERM raloxifene (ral) have major effects o
Autor:
Kristina Eriksson, Merja Nurkkala Karlsson, Lucija Slavica, Marian Kacerovsky, Inger Nordström, Hadi Valadi, Bo Jacobsson
Publikováno v:
Journal of leukocyte biology. 94(5)
Newborns are highly susceptible to viral infections. We hypothesized that this susceptibility could be due to a dysregulated expression of innate virus-sensing receptors, i.e., TLR3, TLR7, TLR8, and TLR9 and the cytosolic receptors retinoic acid-indu
Autor:
Merja Nurkkala Karlsson, Olov Wiklund, Kristina Skålén, Annika Lundqvist, Jan Borén, Max Levin, Lillemor Mattsson Hultén, Lisa U. Magnusson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e43142 (2012)
PLoS ONE, Vol 7, Iss 8, p e43142 (2012)
Inflammation in the vascular wall is important for development of atherosclerosis. We have shown previously that arachidonate 15-lipoxygenase type B (ALOX15B) is more highly expressed in human atherosclerotic lesions than in healthy arteries. This en
Autor:
Louise Grahnemo, Claes Ohlsson, Ulrika Islander, Alexandra Stubelius, Hans Carlsten, Mattias Svensson, Marie K Lagerquist, Annica Andersson, Merja Nurkkala-Karlsson
Publikováno v:
Arthritis Research & Therapy
Introduction Postmenopausal women with rheumatoid arthritis (RA) have increased risk of developing osteoporosis due to chronic inflammation and estrogen deprivation. Collagen antibody-induced arthritis (CAIA), an experimental polyarthritis model repr