Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Merja Haaparanta"'
Autor:
Richard Aarnio, Anna Kirjavainen, Johan Rajander, Sarita Forsback, Kari Kalliokoski, Pirjo Nuutila, Zvonko Milicevic, Tamer Coskun, Axel Haupt, Iina Laitinen, Merja Haaparanta-Solin
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Background Fatty acid uptake can be measured using PET and 14-(R,S)‐[18F]fluoro‐6‐thia‐heptadecanoic acid ([18F]FTHA). However, the relatively rapid rate of [18F]FTHA metabolism significantly affects kinetic modeling of tissue uptake
Externí odkaz:
https://doaj.org/article/431ec5815c0a4c829a4b8d52c133bc9b
Autor:
Obada M. Alzghool, Richard Aarnio, Jatta S. Helin, Saara Wahlroos, Thomas Keller, Markus Matilainen, Junel Solis, Jonathan J. Danon, Michael Kassiou, Anniina Snellman, Olof Solin, Juha O. Rinne, Merja Haaparanta-Solin
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Background P2X7 receptor has emerged as a potentially superior PET imaging marker to TSPO, the gold standard for imaging glial reactivity. [11C]SMW139 is the most recently developed radiotracer to image P2X7 receptor. The aim of this study w
Externí odkaz:
https://doaj.org/article/8e5a36ca8329413fa964965d794781da
Autor:
Obada M. Alzghool, Richard Aarnio, Jatta S. Helin, Saara Wahlroos, Thomas Keller, Markus Matilainen, Junel Solis, Jonathan J. Danon, Michael Kassiou, Anniina Snellman, Olof Solin, Juha O. Rinne, Merja Haaparanta‑Solin
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/ee9a53c14bd24cc0a319604cfc3b1e47
Autor:
Nina Savisto, Tove J. Grönroos, Vesa Oikonen, Johan Rajander, Eliisa Löyttyniemi, Jörgen Bergman, Sarita Forsback, Olof Solin, Merja Haaparanta-Solin
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Background In the development of new 18F-labelled tracers, it is important to assess the amount of released [18F]fluoride taken up in the bones of experimental animals because all 18F-labelled PET-tracers are prone, to lesser or higher degre
Externí odkaz:
https://doaj.org/article/a83345258714455abecae5ef95f56495
Autor:
Gillian Bonvicini, Stina Syvänen, Ken G. Andersson, Merja Haaparanta-Solin, Francisco López-Picón, Dag Sehlin
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-14 (2022)
Abstract Background Hijacking the transferrin receptor (TfR) is an effective strategy to transport amyloid-beta (Aβ) immuno-positron emission tomography (immunoPET) ligands across the blood–brain barrier (BBB). Such ligands are more sensitive and
Externí odkaz:
https://doaj.org/article/ac051588a8784bbeb94c18e3d8ad8f8d
Autor:
Juho R. H. Raiko, Teemu Saari, Janne Orava, Nina Savisto, Riitta Parkkola, Merja Haaparanta‐Solin, Pirjo Nuutila, Kirsi A. Virtanen
Publikováno v:
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract Background Sympathetic activity causes changes in electrocardiogram (ECG) during cold exposure and the changes have been studied mostly during hypothermia and less during mild acute nonshivering cold exposure. Cold‐induced sympathetic acti
Externí odkaz:
https://doaj.org/article/671442e0e2f54e5686b9997b2ff80484
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Chronic inflammation is a common phenomenon present in the background of multiple neurodegenerative diseases, including Alzheimer's disease (AD). The arachidonic acid pathway overproduces proinflammatory eicosanoids during these states and glial cell
Externí odkaz:
https://doaj.org/article/02aabe5fd3e1447dadef5b7af440d276
Autor:
Thomas, Keller, Francisco, López-Picón, Richard, Aarnio, Sarita, Forsback, Anna, Kirjavainen, Merja, Haaparanta-Solin, Olof, Solin
Publikováno v:
In Nuclear Medicine and Biology November-December 2023 126-127 Supplement
Autor:
Richard Aarnio, Semi Helin, Lauri Nummenmaa, Marco Bucci, Annie von Eyken, Tatu Kantonen, Tomi Karjalainen, Kari K. Kalliokoski, Noora Houttu, Tapani Rönnemaa, Laura Pekkarinen, Kirsi Laitinen, Alex M. Dickens, Anna K. Kirjavainen, Jussi Hirvonen, Pirjo Nuutila, Merja Haaparanta-Solin
Publikováno v:
International Journal of Obesity (2005)
Background Obesity is a pressing public health concern worldwide. Novel pharmacological means are urgently needed to combat the increase of obesity and accompanying type 2 diabetes (T2D). Although fully established obesity is associated with neuromol
Autor:
Merja Haaparanta-Solin, Juha O. Rinne, Olof Solin, Diana Bocancea, Jatta S. Helin, Francisco R. López-Picón, Semi Helin, Annelaure Damont, Frédéric Dollé, Thomas Keller, Anna Krzyczmonik
Publikováno v:
Molecular Imaging and Biology
Purpose In this study we compared the recently developed TSPO tracer [18F]F-DPA, with [18F]DPA-714 and [11C]PBR28 by performing in vivo PET imaging on the same Alzheimer’s disease mouse model APP/PS1-21 (TG) and wild-type (WT) mice with all three r