Attenuation of intestinal inflammation in IL-10 deficient mice by a plasmid carrying Lactococcus lactis strain

Autor: Meritxell Zurita-Turk, Bianca Mendes Souza, Camila Prósperi de Castro, Vanessa Bastos Pereira, Vanessa Pecini da Cunha, Tatiane Melo Preisser, Ana Maria Caetano de Faria, Denise Carmona Cara Machado, Anderson Miyoshi

Publikováno v: BMC Biotechnology, Vol 20, Iss 1, Pp 1-12 (2020)

Abstract Background Inflammatory bowel diseases (IBD) are intestinal disorders characterized by inflammation in the gastrointestinal tract (GIT) and to date, no efficient treatments exist. Interleukin-10 (IL-10), one of the most important anti-inflam

Externí odkaz: https://doaj.org/article/b00b8c7cdb9a45308fc4fb7000f1fa15

Lactococcus lactis FNBPA+ (pValac:e6ag85a) Induces Cellular and Humoral Immune Responses After Oral Immunization of Mice

Autor: Janete Soares Coelho dos Santos, Pamela Mancha-Agresti, Sophie Yvette Leclercq, Tatiane Melo Preisser, Vanessa Pecini da Cunha, Vanessa Bastos Pereira, Meritxell Zurita-Turk, Bianca Mendes Souza, Camila Prosperi de Castro, Anderson Miyoshi, Vasco Azevedo

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology

The development of a new vaccine strategy against tuberculosis is urgently needed and has been greatly encouraged by the scientific community worldwide. In this work, we constructed a lactococcal DNA vaccine based on the fusion of two Mycobacterium t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0205a45b3490b866a4f70478511a120
https://www.frontiersin.org/articles/10.3389/fmicb.2021.676172/full

DNA Vaccines Approach: From Concepts to Applications

Autor: Pamela Mancha Agresti, Camila Prosperi de Castro, Daniela Santos Pontes, Vanessa Nathalie Pfeiffer, Marcela Santiago Pacheco Azevedo, Tessália Diniz Luerce Saraiva, Fernanda Alvarenga Lima, Anderson Miyoshi, Clarissa Santos Rocha, Vasco Azevedo, Bianca Mendes Souza, Vanessa Bastos Pereira, Meritxell Zurita-Turk

Publikováno v: World Journal of Vaccines. :50-71

DNA vaccines are the third generation vaccines based on purified plasmid preparations containing transgenes that encode antigenic/therapeutic proteins or peptides capable of triggering an immune response against a wide range of diseases. This vaccine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60e0d9b810465dfb04d8004565f54d85
https://doi.org/10.4236/wjv.2014.42008

Development of a new DNA vaccine based on mycobacterial ESAT-6 antigen delivered by recombinant invasive Lactococcus lactis FnBPA+

Autor: Bianca Mendes Souza, Tessália Diniz Luerce Saraiva, Vanessa Bastos Pereira, Ana Cristina Gomes Santos, Ana Maria Caetano Faria, Camila Prosperi de Castro, Meritxell Zurita-Turk, Anderson Miyoshi, Sophie Yvette Leclercq, Janete Soares Coelho dos Santos, Vasco Azevedo, Marcela Santiago Pacheco Azevedo, Pamela Mancha-Agresti

Publikováno v: Applied microbiology and biotechnology. 99(4)

The use of the food-grade bacterium Lactococcus lactis as a vehicle for the oral delivery of DNA vaccine plasmids constitutes a promising strategy for vaccination. The delivery of DNA plasmids into eukaryotic cells is of critical importance for subse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852aa52e1685a00b01a6546b7e55ce29
https://pubmed.ncbi.nlm.nih.gov/25503506

PANNOTATOR: an automated tool for annotation of pan-genomes

Autor: Ahmed F. Abdelzaher, Neha Jain, Vijender Chaitankar, Eudes Barbosa, Preetam Ghosh, Debmalya Barh, Meritxell Zurita-Turk, Karina K Fiaux, Artur Silva, Bhanu K. Kamapantula, Neha Barve, Anderson Rodrigues dos Santos, Anderson Miyoshi, Vasco Azevedo, Sandeep Tiwari

Publikováno v: Santos, A R, Barbosa, E G V, Fiaux, K, Zurita-Turk, M, Chaitankar, V, Kamapantula, B, Abdelzaher, A, Ghosh, P, Tiwari, S, Barve, N, Jain, N, Barh, D, Silva, A, Miyoshi, A & Azevedo, V 2013, ' PANNOTATOR : an automated tool for annotation of pan-genomes ', Genetics and Molecular Research, vol. 12, no. 3, pp. 2982-9 . https://doi.org/10.4238/2013.August.16.2

Due to next-generation sequence technologies, sequencing of bacterial genomes is no longer one of the main bottlenecks in bacterial research and the number of new genomes deposited in public databases continues to increase at an accelerating rate. Am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8eac4414b4ce73b2578d20f151f6b59
https://pubmed.ncbi.nlm.nih.gov/24065654