Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Meritxell Galindo Casas"'
Autor:
Rachel C Lynn, Purnima Sundar, Omar Ali, Christina Cheung, Shobha Potluri, Meritxell Galindo Casas, Candace Sims, Viola C Lam, Aileen Li, Jessica Barragan, Jessica Briones, Esha Afreen, Grant Vavra, Jia Lu, Rowena Martinez, Christina Ta, Eskedar Nigatu, Alexander S Cheung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/8290649cd6d6401689d7af95ad7d49d4
Autor:
Magdalena Dorywalska, Pavel Strop, Jody A Melton-Witt, Adela Hasa-Moreno, Santiago E Farias, Meritxell Galindo Casas, Kathy Delaria, Victor Lui, Kris Poulsen, Janette Sutton, Gary Bolton, Dahui Zhou, Ludivine Moine, Russell Dushin, Thomas-Toan Tran, Shu-Hui Liu, Mathias Rickert, Davide Foletti, David L Shelton, Jaume Pons, Arvind Rajpal
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132282 (2015)
The efficacy of an antibody-drug conjugate (ADC) is dependent on the properties of its linker-payload which must remain stable while in systemic circulation but undergo efficient processing upon internalization into target cells. Here, we examine the
Externí odkaz:
https://doaj.org/article/523b58d2569a488d9bf12b8cb87145b2
Autor:
Pavel Strop, Arvind Rajpal, David L. Shelton, Jaume Pons, Christopher J. O'Donnell, Davide Foletti, Shu-Hui Liu, Kathy Delaria, Thomas-Toan Tran, Meritxell Galindo Casas, Adela Hasa-Moreno, Victor Lui, Thayalan Navaratnam, Dahui Zhou, Santiago E. Farias, Ludivine Moine, Russell Dushin, Magdalena Dorywalska
Experimental Procedures for the Preparation of Linker-Payloads.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a221c603c7097472189eaf46ce305d
https://doi.org/10.1158/1535-7163.22508245.v1
https://doi.org/10.1158/1535-7163.22508245.v1
Autor:
Pavel Strop, Arvind Rajpal, David L. Shelton, Jaume Pons, Christopher J. O'Donnell, Davide Foletti, Shu-Hui Liu, Kathy Delaria, Thomas-Toan Tran, Meritxell Galindo Casas, Adela Hasa-Moreno, Victor Lui, Thayalan Navaratnam, Dahui Zhou, Santiago E. Farias, Ludivine Moine, Russell Dushin, Magdalena Dorywalska
S1. Enrichment of VC-PABC hydrolysis activity by mouse serum fractionation. S2. Testing of mouse serum enzymes for the VC-PABC linker hydrolysis activity. S3. Testing of mouse serum enzymes for cleavage activity towards the non-cleavable amino-PEG6-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07f5767e7793d3073dc403b33870b7e
https://doi.org/10.1158/1535-7163.22508248
https://doi.org/10.1158/1535-7163.22508248
Autor:
Yogin Patel, Benjamin Harris, Melissa Bedard, Joanna Kritikou, Meritxell Galindo Casas, Carson Harms, Melissa DeFrancesco, Purnima Sundar, Nicholas Restifo, Gary Lee, Shobha Potluri, Suman Kumar Vodnala
Publikováno v:
Regular and Young Investigator Award Abstracts.
Publikováno v:
ACS synthetic biology. 9(11)
The site-specific incorporation of noncanonical amino acids (ncAAs) into proteins by amber stop codon suppression has become a routine method in academic laboratories. This approach requires an amber suppressor tRNACUA to read the amber codon and an
Publikováno v:
Springer Protocols Handbooks ISBN: 9781071607190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fece604dfb148f2bb6f0b08353c581e
https://doi.org/10.1007/978-1-0716-0720-6_14
https://doi.org/10.1007/978-1-0716-0720-6_14
Autor:
Christoph K. Winkler, Kerstin Steiner, Christina Andrea Müller, Wolfgang Schnitzhofer, Christiane Luley-Goedl, Enrique Herrero Acero, Marianne Haberbauer, Regina Kratzer, Tamara Wriessnegger, Meritxell Galindo Casas, Petra Heidinger, Steffen Gruber, Christoph Wilhelm Sensen, Alexander Dennig, Tomislav Cernava, Jung Soh, Katharina Schmölzer, Martina Geier, Birgit Wiltschi, Michael Sauer, Julia Pitzer, Doris Ribitsch, Margit Winkler
Publikováno v:
Biotechnology advances. 40
Competitive sustainable production in industry demands new and better biocatalysts, optimized bioprocesses and cost-effective product recovery. Our review sheds light on the progress made for the individual steps towards these goals, starting with th
Autor:
Wei-Hsien Ho, Oi Kwan Wong, Pavel Strop, David L. Shelton, Meritxell Galindo Casas, Melinda Au, Marjorie Bateman, Thomas-Toan Tran, Kevin Lindquist, Shu-Hui Liu, Arvind Rajpal
Publikováno v:
Oncotarget
Epidermal growth factor receptor (EGFR) is a clinically validated target and often overexpressed in some solid tumors. Both EGFR tyrosine kinase inhibitors and ligand-blocking antibodies have been approved for treatment of NSCLC, head and neck cancer
Autor:
Kathy Delaria, David L. Shelton, Kristian Todd Poulsen, Russell Dushin, Davide Foletti, Shu-Hui Liu, Gary Louis Bolton, Santiago E. Farias, Jaume Pons, Meritxell Galindo Casas, Victor Lui, Thomas-Toan Tran, Stellanie Krimm, Carole M. Loo, Adela Hasa-Moreno, Ludivine Moine, Mathias Rickert, Jody A. Melton-Witt, Magdalena Dorywalska, Pavel Strop, Arvind Rajpal
Publikováno v:
Bioconjugate Chemistry. 26:650-659
The systemic stability of the antibody-drug linker is crucial for delivery of an intact antibody-drug conjugate (ADC) to target-expressing tumors. Linkers stable in circulation but readily processed in the target cell are necessary for both safety an