Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Meritxell Alberich Jordà"'
Autor:
Xinhui Zhao, Boris Bartholdy, Yukiya Yamamoto, Erica K. Evans, Meritxell Alberich-Jordà, Philipp B. Staber, Touati Benoukraf, Pu Zhang, Junyan Zhang, Bon Q. Trinh, John D. Crispino, Trang Hoang, Mahmoud A. Bassal, Daniel G. Tenen
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The transcription factor PU.1 recruits c-Jun as a co-activator to promoters without AP-1 binding sites, and mice with point mutations in PU.1 that disrupts the interaction between PU1 and c-Jun have defects in PU.1 dependent blood lineages, including
Externí odkaz:
https://doaj.org/article/028cca4501134f47a69fa8a2baa9c31b
Autor:
Xinhui Zhao, Boris Bartholdy, Yukiya Yamamoto, Erica K. Evans, Meritxell Alberich-Jordà, Philipp B. Staber, Touati Benoukraf, Pu Zhang, Junyan Zhang, Bon Q. Trinh, John D. Crispino, Trang Hoang, Mahmoud A. Bassal, Daniel G. Tenen
Publikováno v:
Communications biology. 5(1)
The Ets transcription factor PU.1 is essential for inducing the differentiation of monocytes, macrophages, and B cells in fetal liver and adult bone marrow. PU.1 controls hematopoietic differentiation through physical interactions with other transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99dfd2845bd6b5a9da3a302b5334878
https://pubmed.ncbi.nlm.nih.gov/36104445
https://pubmed.ncbi.nlm.nih.gov/36104445
Autor:
Julius Lukes, Jr, Eliska Potuckova, Natividad Alquezar-Artieda, Ivana Hermanova, Sladjana Kosanovic, Katerina Hlozkova, Meritxell Alberich Jorda, Jan Zuna, Jan Trka, Daniel A. Tennant, Martin Stanulla, Marketa Zaliova, Julia Starkova
Publikováno v:
HemaSphere, Vol 7, Iss 9, p e946 (2023)
Externí odkaz:
https://doaj.org/article/38745fd95b8a406db493f1710ead251c
Autor:
Tanya Siddiqi, Meritxell Alberich Jordà, Britta Will, Takeshi Shimamura, Katarina Luptakova, Daniel B. Costa, Ulrich Steidl, Susumu Kobayashi, Daniel G. Tenen, Philipp B. Staber
Publikováno v:
Blood. 115:2901-2909
The activating mutation JAK2 V617F plays a central role in the pathogenesis of polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Inhibition of JAK2 activity leads to growth inhibition and apoptosis in cells with mutated JAK2. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742277e0a01a2124745f77e7b28be30b
https://doi.org/10.1182/blood-2009-03-209544
https://doi.org/10.1182/blood-2009-03-209544
Autor:
Sanghoon Lee, Boris Bartholdy, Constanze Bonifer, Florence Guibal, Maarten Hoogenkamp, Tajhal Dayaram, Pu Zhang, Johanna Klupp, Britta Will, Meritxell Alberich Jordà, Frank Rosenbauer, Katherine L. B. Borden, Alexander K. Ebralidze, Victoria Petkova, Daniel G. Tenen, Gang Huang, Karen B. O'Brien, Ulrich Steidl
Publikováno v:
Genes & Development. 22:2085-2092
The transcription factor PU.1 is an important regulator of hematopoiesis; precise expression levels are critical for normal hematopoietic development and suppression of leukemia. We show here that noncoding antisense RNAs are important modulators of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12aa73ce84af5f16d251c0098be80e03
https://doi.org/10.1101/gad.1654808
https://doi.org/10.1101/gad.1654808
Autor:
Claudia A.J. Erpelinck-Verschueren, Bob Löwenberg, Ruud Delwel, Peter J. M. Valk, Roel G. W. Verhaak, Pu Zhang, Warren S. Pear, Dennis Tielemans, Christopher J. Hetherington, Yiping He, Irene Louwers, Meritxell Alberich Jordà, Yumi Yashiro-Ohtani, Karen Keeshan, Bas J. Wouters, Daniel G. Tenen, Anton W. Langerak
Publikováno v:
Blood, 110(10), 3706-3714. American Society of Hematology
Gene expression profiling of acute myeloid leukemia (AML) allows the discovery of previously unrecognized molecular entities. Here, we identified a specific subgroup of AML, defined by an expression profile resembling that of AMLs with mutations in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a42f0fcd80bc0050cb312e71c928852
https://doi.org/10.1182/blood-2007-02-073486
https://doi.org/10.1182/blood-2007-02-073486
Publikováno v:
Annals of the New York Academy of Sciences. 996:10-16
By means of retroviral insertional mutagenesis, we identified a novel common virus integration site (cVIS) (Evi11) in murine leukemias, and demonstrated that Cb2, encoding the peripheral cannabinoid receptor, is the potential proto-oncogene located i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a546a3158085fff60ac436c313ac4699
https://doi.org/10.1111/j.1749-6632.2003.tb03227.x
https://doi.org/10.1111/j.1749-6632.2003.tb03227.x
Autor:
Ruud Delwel, Sandra E. Verbakel, M. Maccarrone, Meritxell Alberich Jordà, Peter J. M. Valk, Allessandro Finazzi-Agrò, Yolanda Vankan-Berkhoudt, Bob Löwenberg
Publikováno v:
Blood, 99, 2786-2793. American Society of Hematology
Cb2 is a novel protooncogene encoding the peripheral cannabinoid receptor. Previous studies demonstrated that 2 distinct noncoding first exons exist: exon-1A and exon-1B, which both splice to protein-coding exon-2. We demonstrate that in retrovirally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c35d8af99563c7a9b9aea38b1b5f91f
https://doi.org/10.1182/blood.V99.8.2786
https://doi.org/10.1182/blood.V99.8.2786
Autor:
Eliska Doktorova, Julia Starkova, Jiri Petrak, J.H. Frederik Falkenburg, Jan Zuna, Olga Zimmermannova, Jan Trka, Jan Stuchly, Marketa Zaliova, Meritxell Alberich Jordà
Publikováno v:
Blood. 128:751-751
Leukemias harboring ETV6-ABL1 fusion represent a rare prognostically unfavorable subgroup of hematological malignancies. To a great extent they share biological and clinical characteristics with more common BCR-ABL1+ leukemias. Both fusion genes enco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d282746ab1bd79607fed7ef4b169ab5
https://doi.org/10.1182/blood.v128.22.751.751
https://doi.org/10.1182/blood.v128.22.751.751
Autor:
Sandra E. Verbakel, Nazik Rayman, Mauro Maccarrone, Marjolein Tas, Ruud Delwel, Kirsten van Lom, Natalia Battista, Meritxell Alberich Jordà, Bob Löwenberg
Publikováno v:
Blood, 104, 526-534. American Society of Hematology
Cb2, the gene encoding the peripheral cannabinoid receptor, is located in a common virus integration site and is overex-pressed in retrovirally induced murine myeloid leukemias. Here we show that this G protein-coupled receptor (GPCR) is also aberran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b96851416096aac62d442a7ef12d59
https://pure.eur.nl/en/publications/9b2b0696-97d0-477c-bf79-0fbed7daef47
https://pure.eur.nl/en/publications/9b2b0696-97d0-477c-bf79-0fbed7daef47
