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of 8
pro vyhledávání: '"Merilyn H. Hibma"'
Autor:
Merilyn H. Hibma
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 37:467-468
Autor:
Nor Malia Abd Warif, Patrizia Stoitzner, Graham R Leggatt, Stephen R Mattarollo, Ian H Frazer, Merilyn H Hibma
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127155 (2015)
It has previously been shown that expression of human papillomavirus type 16 (HPV) E7 in epidermis causes hyperplasia and chronic inflammation, characteristics of pre-malignant lesions. Importantly, E7-expressing epidermis is strongly immune suppress
Externí odkaz:
https://doaj.org/article/497eae8c5deb4227ab151c595120b32d
Autor:
Zarina J D'Costa, Carol Jolly, Elliot J Androphy, Andrew Mercer, Charles M Matthews, Merilyn H Hibma
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48954 (2012)
There is increasing evidence supporting DNA virus regulation of the cell adhesion and tumour suppressor protein, E-cadherin. We previously reported that loss of E-cadherin in human papillomavirus (HPV) type 16-infected epidermis is contributed to by
Externí odkaz:
https://doaj.org/article/40b7481db6184d22adfc0ae9058aa885
Publikováno v:
European Journal of Biochemistry. 229:517-525
Replication of papillomavirus DNA requires two virally encoded proteins, El and E2. We expressed human papillomavirus (HPV) type 16 El and E2 in bacteria and showed that purified full-length E2 protein interacted directly with El, in the absence of H
Publikováno v:
The Journal of investigative dermatology. 130(2)
Human papillomaviruses (HPVs), which are contained in the alpha, beta, gamma, mu, and nu genera, differ in their oncogenic potential and their tropism for cutaneous or mucosal epidermis. Langerhans cells (LC), the only epidermal professional antigen-
Publikováno v:
Nucleic acids research. 22(18)
Autor:
G Van Nest, M. Contorni, Sarah J. Ely, Merilyn H. Hibma, Rino Rappuoli, M. Tommasino, L. Crawford
Publikováno v:
Immunology of Human Papillomaviruses ISBN: 9781461360414
There is a strong association between the presence of HPV DNA and the transformation of cervical. tissue to malignancy. This link provides a rare opportunity to target a tumour immunologically through specific proteins of the causal. agent. Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::111ffbd4b28b4dc05563ae7219850cf2
https://doi.org/10.1007/978-1-4615-2449-6_45
https://doi.org/10.1007/978-1-4615-2449-6_45
Publikováno v:
Virology. 187(1)
The human papillomavirus (HPV) E1--E4 protein is the only nonstructural late protein encoded by the virus. We have isolated three hybridomas producing monoclonal antibodies to the E1--E4 protein of HPV16, which is the HPV type most frequently associa