Estimating associations between antidepressant use and incident mild cognitive impairment in older adults with depression.

Autor: Fang Han, Tyler Bonnett, Willa D Brenowitz, Merilee A Teylan, Lilah M Besser, Yen-Chi Chen, Gary Chan, Ke-Gang Cao, Ying Gao, Xiao-Hua Zhou

Publikováno v: PLoS ONE, Vol 15, Iss 1, p e0227924 (2020)

IntroductionPrevious studies have provided equivocal evidence of antidepressant use on subsequent cognitive impairment; this could be due to inconsistent modeling approaches. Our goals are methodological and clinical. We evaluate the impact of statis

Externí odkaz: https://doaj.org/article/830a0b5dd5c8420f830bafdda6d656eb

Symptomatic Profile and Cognitive Performance in Autopsy-Confirmed Limbic-Predominant Age-Related TDP-43 Encephalopathy With Comorbid Alzheimer Disease

Autor: Kathryn, Gauthreaux, Charles, Mock, Merilee A, Teylan, Jessica E, Culhane, Yen-Chi, Chen, Kwun C G, Chan, Yuriko, Katsumata, Peter T, Nelson, Walter A, Kukull

Publikováno v: Journal of Neuropathology & Experimental Neurology. 81:975-987

Transactive response DNA-binding protein 43 kDa (TDP-43) proteinopathy is the hallmark of limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC). LATE-NC is a common copathology with Alzheimer disease neuropathologic ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3994e19978f04b6c71c951899eea2ccf
https://doi.org/10.1093/jnen/nlac093

Divergent magnetic resonance imaging atrophy patterns in Alzheimer’s disease and primary age‐related tauopathy

Autor: Miguel Quintas‐Neves, Merilee A. Teylan, Rafaela Morais‐Ribeiro, Francisco Almeida, Charles Mock, Walter A. Kukull, John F. Crary, Tiago Gil Oliveira

Publikováno v: Alzheimer's & Dementia. 18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9114c9d0fd12e28827b6a868a8cdb7e0
https://doi.org/10.1002/alz.067568

Limbic-Predominant Age-Related TDP-43 Encephalopathy: Medical and Pathologic Factors Associated With Comorbid Hippocampal Sclerosis

Autor: Kathryn M. Gauthreaux, Merilee A. Teylan, Yuriko Katsumata, Charles Mock, Jessica E. Culhane, Yen-Chi Chen, Kwun C.G. Chan, David W. Fardo, Adam J. Dugan, Matthew D. Cykowski, Gregory A. Jicha, Walter A. Kukull, Peter T. Nelson

Publikováno v: Neurology

Background and ObjectivesLimbic-predominant age-related Tar DNA binding protein 43 (TDP-43) encephalopathy neuropathologic change (LATE-NC) is present in ≈25% of older persons' brains and is strongly associated with cognitive impairment. Hippocampa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c04f72b0ae934e66dc04bac34855b15
https://europepmc.org/articles/PMC8992604/

Brain arteriolosclerosis

Autor: Brittney L. Blevins, Harry V. Vinters, Seth Love, Donna M. Wilcock, Lea T. Grinberg, Julie A. Schneider, Rajesh N. Kalaria, Yuriko Katsumata, Brian T. Gold, Danny J. J. Wang, Samantha J. Ma, Lincoln M. P. Shade, David W. Fardo, Anika M. S. Hartz, Gregory A. Jicha, Karin B. Nelson, Shino D. Magaki, Frederick A. Schmitt, Merilee A. Teylan, Eseosa T. Ighodaro, Panhavuth Phe, Erin L. Abner, Matthew D. Cykowski, Linda J. Van Eldik, Peter T. Nelson

Publikováno v: Blevins, B L, Vinters, H V, Love, S, Wilcock, D M, Grinberg, L T, Schneider, J A, Kalaria, R N, Katsumata, Y, Gold, B T, Wang, D J J, Ma, S J, Shade, L M P, Fardo, D W, Hartz, A M S, Jicha, G A, Nelson, K B, Magaki, S D, Schmitt, F A, Teylan, M A, Ighodaro, E T, Phe, P, Abner, E L, Cykowski, M D, Van Eldik, L J & Nelson, P T 2021, ' Brain arteriolosclerosis ', Acta Neuropathologica, vol. 141, no. 1, pp. 1-24 . https://doi.org/10.1007/s00401-020-02235-6
Acta Neuropathol
Acta neuropathologica, vol 141, iss 1

Brain arteriolosclerosis (B-ASC), characterized by pathologic arteriolar wall thickening, is a common finding at autopsy in aged persons and is associated with cognitive impairment. Hypertension and diabetes are widely recognized as risk factors for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c9a61359bf852bc16d85526345df32
https://research-information.bris.ac.uk/en/publications/1199021b-7f43-4a1e-89e0-a1b3a5b57078