Novel sulfamethoxazole and 1-(2-fluorophenyl) piperazine derivatives as potential apoptotic and antiproliferative agents by inhibition of BCL2; design, synthesis, biological evaluation, and docking studies.

Autor: Vadabingi N; Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh India., Mallepogu V; Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India., Mallapu RE; Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh India., Pasala C; Bioinformatics Centre, Department of Bioinformatics, SVIMS University, Tirupati, Andhra Pradesh India., Poreddy S; Department of Chemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh India., Bellala P; Department of Chemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh India., Amineni U; Bioinformatics Centre, Department of Bioinformatics, SVIMS University, Tirupati, Andhra Pradesh India., Cirandur SR; Department of Chemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh India., Meriga B; Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India.

Publikováno v: 3 Biotech [3 Biotech] 2024 Nov; Vol. 14 (11), pp. 269. Date of Electronic Publication: 2024 Oct 15.

Ursolic acid regulates key EMT transcription factors, induces cell cycle arrest and apoptosis in MDA-MB-231 and MCF-7 breast cancer cells, an in-vitro and in silico studies.

Autor: Mallepogu V; Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh, India., Sankaran KR; Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh, India., Pasala C; Department of Bioinformatics, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India., Bandi LR; Department of Zoology, Sri Venkateswara University, Tirupati, Andhra Pradesh, India., Maram R; Department of Zoology, Sri Venkateswara University, Tirupati, Andhra Pradesh, India., Amineni UM; Department of Bioinformatics, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India., Meriga B; Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh, India.

Publikováno v: Journal of cellular biochemistry [J Cell Biochem] 2023 Dec; Vol. 124 (12), pp. 1900-1918. Date of Electronic Publication: 2023 Nov 22.

Thymoquinone mitigates obesity and diabetic parameters through regulation of major adipokines, key lipid metabolizing enzymes and AMPK/p-AMPK in diet-induced obese rats.

Autor: Ramineedu K; Division of Cell Culture and Molecular Biology, Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India., Sankaran KR; Division of Cell Culture and Molecular Biology, Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India., Mallepogu V; Division of Cell Culture and Molecular Biology, Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India., Rendedula DP; GVK Biosciences, Hyderabad, Telangana India., Gunturu R; GVK Biosciences, Hyderabad, Telangana India., Gandham S; Department of ECE, Siddartha Educational Academy Group of Institutions, Tirupati, AP 517502 India., Md SI; Department of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4000 South Africa., Meriga B; Division of Cell Culture and Molecular Biology, Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India.

Publikováno v: 3 Biotech [3 Biotech] 2024 Jan; Vol. 14 (1), pp. 16. Date of Electronic Publication: 2023 Dec 18.

Capparis zeylanica L. root extract promotes apoptosis and cell cycle arrest, inhibits epithelial-to-mesenchymal transition and triggers E-cadherin expression in breast cancer cell lines.

Autor: Venkataswamy M; Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India., Karunakaran RS; Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India., Islam MS; Department of Biochemistry, School of Life Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4000 South Africa., Meriga B; Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh 517502 India.

Publikováno v: 3 Biotech [3 Biotech] 2023 Feb; Vol. 13 (2), pp. 41. Date of Electronic Publication: 2023 Jan 10.

Quercetin-3- O -rutinoside from Moringa oleifera Downregulates Adipogenesis and Lipid Accumulation and Improves Glucose Uptake by Activation of AMPK/Glut-4 in 3T3-L1 Cells.

Autor: Ganjayi MS; Division of Cell Culture and Molecular Biology, Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh India., Karunakaran RS; Division of Cell Culture and Molecular Biology, Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh India., Gandham S; Department of Electronics and Communication Engineering, Sri Venkateswara University College of Engineering, Andhra Pradesh Tirupati, India., Meriga B; Division of Cell Culture and Molecular Biology, Department of Biochemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh India.

Publikováno v: Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia [Rev Bras Farmacogn] 2023; Vol. 33 (2), pp. 334-343. Date of Electronic Publication: 2023 Feb 13.