Výsledky vyhledávání - "Meriet Mikhail"

First demonstration of a lack of viral sequence evolution in a nonprogressor, defining replication-incompetent HIV-1 infection

Autor: Meriet Mikhail, Bin Wang, Anthony D. Kelleher, Wayne B. Dyer, John Zaunders, Nitin K. Saksena

Publikováno v: Virology. 312:135-150

It is universally acknowledged that genetic diversity is a hallmark of HIV-1 infection, and it is one of the traits that has considerably hampered the development of an effective vaccine. In a study of full-length HIV-1 genomic sequences (>9 kb), we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c3192afd124da12d1cd66a41073513
https://doi.org/10.1016/s0042-6822(03)00159-4

Zobrazit plný text záznamu

Comprehensive Analyses of a Unique HIV-1-Infected Nonprogressor Reveal a Complex Association of Immunobiological Mechanisms in the Context of Replication-Incompetent Infection

Autor: Wayne B. Dyer, John Zaunders, Graeme Harris, Meriet Mikhail, John Sullivan, Bin Wang, David A. Cooper, John A.G. Holt, Ross A. Boadle, Lisa A. Williams, Monica Miranda-Saksena, Nitin K. Saksena, Anthony D. Kelleher, Da'ed N. Haddad

Publikováno v: Virology. 304(2):246-264

We recently demonstrated that a unique HIV-1-infected nonprogressor was infected with a nonevolving replication-incompetent HIV-1 strain, showing a total absence of viral evolution in vivo. Potent immune responses against HIV-1 were observed in his P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9453826cd9ae283664ae3a584ed0f7e

Zobrazit plný text záznamu

Evidence for host-driven selection of the HIV type 1 vpr gene in vivo during HIV disease progression in a transfusion-acquired cohort

Autor: Bin Wang, Michael Gill, Meriet Mikhail, David A. Jans, Marco Salemi, Nitin K. Saksena, Leon Cali, Sabine C. Piller, Brenda Beckthold

Publikováno v: AIDS research and human retroviruses. 21(8)

An epidemiologically linked HIV-1-infected cohort, in which a nonprogressor donor infected two recipients who progressed to AIDS, was examined. Sequence analysis, over time, of HIV-1 vpr gene quasispecies from uncultured peripheral blood cells reveal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d405bfe6d2ec29726c6b4e9e6497d2d7
https://pubmed.ncbi.nlm.nih.gov/16131313

Zobrazit plný text záznamu

Full-length HIV type 1 genome analysis showing evidence for HIV type 1 transmission from a nonprogressor to two recipients who progressed to AIDS

Autor: Nitin K. Saksena, Bin Wang, Phillipe Lemey, Anne-Mieke Vandamme, Meriet Mikhail, Brenda Beckholdt, Michael Gill

Publikováno v: AIDS research and human retroviruses. 21(6)

Epidemiologically-linked HIV-1 transmission cohorts serve as excellent models to study HIV disease progression. The actual relationship between viral variability and HIV disease outcome can be extrapolated only through such rare epidemiologically lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c115048b51ade7ef023ffc20279ba0f2
https://pubmed.ncbi.nlm.nih.gov/15989463

Zobrazit plný text záznamu

Role of viral evolutionary rate in HIV-1 disease progression in a linked cohort

Autor: M. John Gill, Nitin K. Saksena, Meriet Mikhail, Brenda Beckthold, Anne-Mieke Vandamme, Philippe Lemey, Bin Wang

Publikováno v: Retrovirology, Vol 2, Iss 1, p 41 (2005)
Retrovirology

Background The actual relationship between viral variability and HIV disease progression and/or non-progression can only be extrapolated through epidemiologically-linked HIV-infected cohorts. The rarity of such cohorts accents their existence as inva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a608af55345d275feade90ec1dbfc4
http://www.retrovirology.com/content/2/1/41

Zobrazit plný text záznamu

Mechanisms involved in non-progressive HIV disease

Autor: Meriet, Mikhail, Bin, Wang, Nitin K, Saksena

Publikováno v: AIDS reviews. 5(4)

HIV disease is a culmination of a complex interplay between both viral and host factors. As the underlying biological and molecular mechanisms involved in determining disease status are not fully understood, the relationship between the two can be be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d7bcdae9742cd9b96caef893698e8073
https://pubmed.ncbi.nlm.nih.gov/15012002

Zobrazit plný text záznamu