Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Meriem Khedraoui"'
Autor:
Amneh Shtaiwi, Shafi Ullah Khan, Meriem Khedraoui, Mohd Alaraj, Abdelouahid Samadi, Samir Chtita
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Peptidoglycan is a carbohydrate with a cross-linked structure that protects the cytoplasmic membrane of bacterial cells from damage. The mechanism of peptidoglycan biosynthesis involves the main synthesizing enzyme glycosyltransferase MurG,
Externí odkaz:
https://doaj.org/article/aba60eb070e14f04b507a4c453790b25
Autor:
Imane Yamari, Oussama Abchir, Hassan Nour, Meriem Khedraoui, Bouchra Rossafi, Abdelkbir Errougui, Mohammed Talbi, Abdelouahid Samadi, MHammed El Kouali, Samir Chtita
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 886 (2024)
Candida albicans and Aspergillus fumigatus are recognized as significant fungal pathogens, responsible for various human infections. The rapid emergence of drug-resistant strains among these fungi requires the identification and development of innova
Externí odkaz:
https://doaj.org/article/a2a8b695a815431981f09946be22d73a
Autor:
Meriem Khedraoui, Oussama Abchir, Hassan Nour, Imane Yamari, Abdelkbir Errougui, Abdelouahid Samadi, Samir Chtita
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 830 (2024)
Acetylcholinesterase (AChE) is one of the main drug targets for treating Alzheimer’s disease. This current study relies on multiple molecular modeling approaches to develop new potent inhibitors of AChE. We explored a 2D QSAR study using the statis
Externí odkaz:
https://doaj.org/article/c00fe19394ff443cb34ebc70bf5b8b8d
Autor:
Oussama Abchir, Meriem Khedraoui, Imane Yamari, Hassan Nour, Abdelkbir Errougui, Abdelouahid Samadi, Samir Chtita
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0308308 (2024)
BackgroundThe increasing prevalence of diabetes and the side effects associated with current medications necessitate the development of novel candidate drugs targeting alpha-glucosidase as a potential treatment option.MethodsThis study employed compu
Externí odkaz:
https://doaj.org/article/e66078124efb4f0697ea528c611cb402
Autor:
Meriem Khedraoui, Hassan Nour, Imane Yamari, Oussama Abchir, Abdelkbir Errougui, Samir Chtita
Publikováno v:
Chemical Physics Impact, Vol 7, Iss , Pp 100361- (2023)
A series of 32 molecules derived from 7-prenyloxy-2,3-dihydroflavanone and 5‑hydroxy-7-prenyloxy-2,3-dihydro-flavanone possessing an inhibitory activity against the Acetylcholinesterase (AChE) enzyme were studied using the structure-activity (QSAR)
Externí odkaz:
https://doaj.org/article/276b9169f3d34ac58be2e348a88782ec
Autor:
Oussama Abchir, Meriem Khedraoui, Hassan Nour, Imane Yamari, Abdelkbir Errougui, Abdelouahid Samadi, Samir Chtita
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 261 (2024)
In response to the increasing prevalence of diabetes mellitus and the limitations associated with the current treatments, there is a growing need to develop novel medications for this disease. This study is focused on creating new compounds that exhi
Externí odkaz:
https://doaj.org/article/da8e5f1f5a764cbf960b7eb26891b1c3