Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Meriem Hechmi"'
Autor:
Ismail Gouiza, Meriem Hechmi, Abir Zioudi, Hamza Dallali, Nadia Kheriji, Majida Charif, Morgane Le Mao, Said Galai, Lilia Kraoua, Ilhem Ben Youssef-Turki, Ichraf Kraoua, Guy Lenaers, Rym Kefi
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
Introduction: Inherited mitochondrial diseases are the most common group of metabolic disorders caused by a defect in oxidative phosphorylation. They are characterized by a wide clinical and genetic spectrum and can manifest at any age. In this study
Externí odkaz:
https://doaj.org/article/d0d0662ffbeb44a0b3f31c44fdd41dc5
Autor:
Hamza Dallali, Wided Boukhalfa, Nadia Kheriji, Meriem Fassatoui, Haifa Jmel, Meriem Hechmi, Ismail Gouiza, Mariem Gharbi, Wafa Kammoun, Mehdi Mrad, Marouen Taoueb, Asma Krir, Hajer Trabelsi, Afef Bahlous, Henda Jamoussi, Olfa Messaoud, Abdelmajid Abid, Rym Kefi
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionType 2 diabetes (T2D) is a multifactorial disease involving genetic and environmental components. Several genome-wide association studies (GWAS) have been conducted to decipher potential genetic aberrations promoting the onset of this met
Externí odkaz:
https://doaj.org/article/ec2f2977e6d94ae5b458346728bffc4e
Autor:
Nadia Kheriji, Hamza Dallali, Ismail Gouiza, Meriem Hechmi, Faten Mahjoub, Mehdi Mrad, Asma Krir, Manel Soltani, Hajer Trabelsi, Walid Hamdi, Afef Bahlous, Melika Ben Ahmed, Henda Jamoussi, Rym Kefi
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Monogenic diabetes (MD) accounts for 3%–6% of all cases of diabetes. This prevalence is underestimated due to its overlapping clinical features with type 1 and type 2 diabetes. Hence, genetic testing is the most appropriate tool for o
Externí odkaz:
https://doaj.org/article/85bbbf73920242eda3ed84cba86223cf
Autor:
Hamza Dallali, Meriem Hechmi, Imane Morjane, Sahar Elouej, Haifa Jmel, Yosra Ben Halima, Abdelmajid Abid, Afef Bahlous, Abdelhamid Barakat, Henda Jamoussi, Sonia Abdelhak, Rym Kefi
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Background Variants in the Hepatocyte Nuclear Factor 1 Alpha gene (HNF1A) are associated with lipoproteins levels and type 2 diabetes. In this study, we aimed to assess the association of HNF1A gene and haplotypes with the metabolic syndrome
Externí odkaz:
https://doaj.org/article/83976765788742f1a3bf0aa0de69fd51
Autor:
Nadia Kheriji, Wided Boukhalfa, Faten Mahjoub, Meriem Hechmi, Thouraya Dakhlaoui, Mehdi Mrad, Afef Hadj Salah Bahlous, Nadia Ben Amor, Henda Jamoussi, Rym Kefi
Publikováno v:
Nutrients, Vol 14, Iss 10, p 2132 (2022)
The prevalence of Type 2 diabetes (T2D) is increasing worldwide. Genetics and lifestyle, especially diet, are contributing factors. Analyses of macro- and micronutrient intake across global populations may help to explain their impact on glucose home
Externí odkaz:
https://doaj.org/article/e6d69b14ac8e48438cae3cc85c93e6ee
Autor:
Rahma Mkaouar, Zied Riahi, Cherine Charfeddine, Imen Chelly, Hela Boudabbous, Hamza Dallali, Crystel Bonnet, Meriem Hechmi, Soumeya Bekri, Nadia Zitouna, Lotfi Zekri, Amel Tounsi, Rym Kefi, Jihene Marrakchi, Olfa Messaoud, Ichraf Kraoua, Sonia Maalej, Ilhem Turki Ben Youssef, Ahlem Ben Hmid, Fabrice Giraudet, Sami Bouchoucha, Neji Tebib, Ghazi Besbes, Christine Petit, Ridha Mrad, Sonia Abdelhak, Mediha Trabelsi
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258202 (2021)
Alpha-Mannosidosis (AM) is an ultra-rare storage disorder caused by a deficiency of lysosomal alpha-mannosidase encoded by the MAN2B1 gene. Clinical presentation of AM includes mental retardation, recurrent infections, hearing loss, dysmorphic featur
Externí odkaz:
https://doaj.org/article/569f864a04af411d83938661f5680131
Autor:
Haifa Jmel, Lilia Romdhane, Yosra Ben Halima, Meriem Hechmi, Chokri Naouali, Hamza Dallali, Yosr Hamdi, Jingxuan Shan, Abdelmajid Abid, Henda Jamoussi, Sameh Trabelsi, Lotfi Chouchane, Donata Luiselli, Sonia Abdelhak, Rym Kefi
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194842 (2018)
Genetic variation is an important determinant affecting either drug response or susceptibility to adverse drug reactions. Several studies have highlighted the importance of ethnicity in influencing drug response variability that should be considered
Externí odkaz:
https://doaj.org/article/750c463436b44044b9ff16d1f5bbd813
Autor:
Meriem Hechmi, Majida Charif, Ichraf Kraoua, Meriem Fassatoui, Hamza Dallali, Valerie Desquiret-Dumas, Céline Bris, David Goudenège, Cyrine Drissi, Saïd Galaï, Slah Ouerhani, Vincent Procaccio, Patrizia Amati-Bonneau, Sonia Abdelhak, Ilhem Ben Youssef-Turki, Guy Lenaers, Rym Kefi
Publikováno v:
Bioscience Reports. 42
Mitochondrial cytopathies, among which the Leigh syndrome (LS), are caused by variants either in the mitochondrial or the nuclear genome, affecting the oxidative phosphorylation process. The aim of the present study consisted in defining the molecula
Autor:
Soumeya Bekri, Olfa Messaoud, Cherine Charfeddine, Hela Boudabbous, Amel Tounsi, Meriem Hechmi, Lotfi Zekri, Rahma Mkaouar, Ghazi Besbes, Ahlem Ben Hmid, Christine Petit, R. M’rad, Neji Tebib, Sami Bouchoucha, Fabrice Giraudet, Rym Kefi, J. Marrakchi, Crystel Bonnet, Imen Chelly, Ichraf Kraoua, Hamza Dallali, Ilhem Turki Ben Youssef, Sonia Abdelhak, Nadia Zitouna, Zied Riahi, Sonia Maalej, Mediha Trabelsi
Publikováno v:
PLoS ONE
PLoS ONE, 2021, 16 (10), pp.e0258202. ⟨10.1371/journal.pone.0258202⟩
PLoS ONE, Vol 16, Iss 10, p e0258202 (2021)
PLoS ONE, 2021, 16 (10), pp.e0258202. ⟨10.1371/journal.pone.0258202⟩
PLoS ONE, Vol 16, Iss 10, p e0258202 (2021)
Alpha-Mannosidosis (AM) is an ultra-rare storage disorder caused by a deficiency of lysosomal alpha-mannosidase encoded by the MAN2B1 gene. Clinical presentation of AM includes mental retardation, recurrent infections, hearing loss, dysmorphic featur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10eed9fa8dee83d1c67ef18ba710098
https://hal-pasteur.archives-ouvertes.fr/pasteur-04072687
https://hal-pasteur.archives-ouvertes.fr/pasteur-04072687
Autor:
Afaf Bahlous, Yossra Ben Halima, Rym Kefi, Abdelhamid Barakat, Haifa Jmel, Meriem Hechmi, Meriem Fassatoui, Hamza Dallali, Sonia Bahri, Henda Jamoussi, Meriem Gharbi, Abdelmajid Abid
Publikováno v:
Bioscience Reports
Apolipoprotein A5 (APOA5) has been linked to metabolic syndrome (MetS) in several populations. In North Africa, only the Tunisian and Moroccan populations were investigated. Our aim is to assess the association between APOA5 gene variant (rs662799) a