Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Meriem Hasmim"'
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
CD73 is an emerging target in cancer due to its role in generating adenosine, a potent immunosuppressor. We found that SNAI1, a driver of epithelial-to-mesenchymal transition (EMT), upregulates CD73 in triple negative breast cancer cells. Here, we di
Externí odkaz:
https://doaj.org/article/c23e26de533c482294c3b7e2948b5915
Autor:
Meriem Hasmim, Malina Xiao, Kris Van Moer, Akinchan Kumar, Alexandra Oniga, Michel Mittelbronn, Caroline Duhem, Anwar Chammout, Guy Berchem, Jean Paul Thiery, Marianna Volpert, Brett Hollier, Muhammad Zaeem Noman, Bassam Janji
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Triple-negative subtype of breast cancer (TNBC) is hallmarked by frequent disease relapse and shows highest mortality rate. Although PD-1/PD-L1 immune checkpoint blockades have recently shown promising clinical benefits, the overall response rate rem
Externí odkaz:
https://doaj.org/article/35d1f9ea5edc46af8039bc9506e5c176
Autor:
Malina Xiao, Alice Benoit, Meriem Hasmim, Caroline Duhem, Guillaume Vogin, Guy Berchem, Muhammad Zaeem Noman, Bassam Janji
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Autophagy is a highly regulated multi-step process that occurs at the basal level in almost all cells. Although the deregulation of the autophagy process has been described in several pathologies, the role of autophagy in cancer as a cytoprotective m
Externí odkaz:
https://doaj.org/article/e4db7c7526394c549c53f4abda3f7663
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Cancer immunotherapy based on anti-PD-1/PD-L1 blockade is particularly effective in responding to patients with hot tumors. These tumors are characterized by the accumulation of proinflammatory cytokines and T cell infiltration. In our recent report
Externí odkaz:
https://doaj.org/article/b66f359dbbd9444c8f7c692b71fd8b94
Autor:
Meriem Hasmim, Nadine Khalife, Yanyan Zhang, Manale Doldur, Geralidne Visentin, Stéphane Terry, Julien Giron-Michel, Ruoping Tang, François Delhommeau, Nicolas Dulphy, Jean-Henri Bourhis, Fawzia Louache, Salem Chouaib
Publikováno v:
OncoImmunology, Vol 6, Iss 10 (2017)
The administration of ex vivo-expanded Natural Killer (NK) cells in leukemia therapy is still challenging, in part due to the difficulty to generate in sufficient quantities fully mature and functional NK cells and Identification of surface markers i
Externí odkaz:
https://doaj.org/article/8f359172b5e04f21be1451a7b6cd0752
Autor:
Muhammad Zaeem Noman, Meriem Hasmim, Audrey Lequeux, Malina Xiao, Caroline Duhem, Salem Chouaib, Guy Berchem, Bassam Janji
Publikováno v:
Cells, Vol 8, Iss 9, p 1083 (2019)
Initially believed to be a disease of deregulated cellular and genetic expression, cancer is now also considered a disease of the tumor microenvironment. Over the past two decades, significant and rapid progress has been made to understand the comple
Externí odkaz:
https://doaj.org/article/0c0070b69ba54e28aeb7eed70b49ba7e
Autor:
Jane Muret, Meriem Hasmim, Izabela Stasik, Abdelali Jalil, Aude Mallavialle, Arash Nanbakhsh, Ludovic Lacroix, Katy Billot, Véronique Baud, Jérome Thiery, Philippe Vielh, Philippe Terrier, Joelle Wiels, Lyubomir Vassilev, Axel Lecesne, Sylvie Bonvalot, Salem Chouaib
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38808 (2012)
BackgroundIsolated limb perfusion with TNF-α and melphalan is used with remarkable efficiency to treat unresectable limb sarcomas. Here we tested the ability of TNF-α to directly induce apoptosis of sarcoma cells. In addition, we investigated the i
Externí odkaz:
https://doaj.org/article/d7f4a17893274733b648d7cb83c3aa30
Autor:
Salem Chouaib, Fathia Mami-Chouaib, Jean Paul Thiery, Nicole Tsang Ying Hung, Joan Herr Keira, Tuan Zea Tan, Michèle Sabbah, Annette K. Larsen, Philippe Vielh, Cécile Badoual, Philippe Bertheau, Patricia De Cremoux, Fabrice André, Muhammad Zaeem Noman, Meriem Hasmim, Bassam Janji, Intissar Akalay
PDF file - 108K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a483f689d75583aa6628050908c8b9a
https://doi.org/10.1158/0008-5472.22398974.v1
https://doi.org/10.1158/0008-5472.22398974.v1
Autor:
Salem Chouaib, Bernard Escudier, Daniel Olive, Jerome Thiery, Laurence Albiges, Florence Orlanducci, Betty Gardie, Sophie Couve, Emmanuel Donnadieu, Sophie Ferlicot, Catherine Richon, Thouraya Ben Safta, Arash Nanbakhsh, Katy Billot, Elodie Viry, Véronique Baud, Marie Boutet, Andrés Tittarelli, Bassam Janji, Meriem Hasmim, Muhammad Zaeem Noman, Yosra Messai
Supplemental video 1. 786-0 cells described in Figure 3B were recorded by time-lapse video microscopy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38cf1c8620935df3cd74c3d4bba2dcc3
https://doi.org/10.1158/0008-5472.22404966.v1
https://doi.org/10.1158/0008-5472.22404966.v1
Autor:
Salem Chouaib, Fathia Mami-Chouaib, Jean Paul Thiery, Nicole Tsang Ying Hung, Joan Herr Keira, Tuan Zea Tan, Michèle Sabbah, Annette K. Larsen, Philippe Vielh, Cécile Badoual, Philippe Bertheau, Patricia De Cremoux, Fabrice André, Muhammad Zaeem Noman, Meriem Hasmim, Bassam Janji, Intissar Akalay
PDF file - 317K, List of EMT- and autophagy-related differentially expressed genes in SNAI1- and SNAI1-6SA-expressing MCF-7 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0db3fb5f22ae50dab475abafe5b3e2
https://doi.org/10.1158/0008-5472.22398983.v1
https://doi.org/10.1158/0008-5472.22398983.v1