Thiadiazoline- and Pyrazoline-Based Carboxamides and Carbothioamides: Synthesis and Inhibition against Nitric Oxide Synthase

Autor: Fabio Arias, M. Encarnación Camacho, M. Dora Carrión, Meriem Chayah, Miguel Romero, Juan Duarte, Miguel A. Gallo

Publikováno v: Journal of Chemistry, Vol 2018 (2018)

Two new families of pyrazoline and thiadiazoline heterocycles have been developed. Their inhibitory activities against two different isoforms of nitric oxide synthase (inducible and neuronal NOS) are reported. The novel derivatives were synthesized c

Externí odkaz: https://doaj.org/article/59a3c0e1dfad444fb3f3f0b639b7a771

Melatonin Improves Mitochondrial Dynamics and Function in the Kidney of Zücker Diabetic Fatty Rats

Autor: Gumersindo Fernández-Vázquez, Russel J. Reiter, Mohamed Tassi, J.M.R. Ferrer, Ahmad Agil, Miguel Navarro-Alarcón, Lucia Visiedo, Meriem Chayah

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
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Journal of Clinical Medicine, Vol 9, Iss 2916, p 2916 (2020)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Journal of Clinical Medicine
Volume 9
Issue 9

Obesity and associated diabetes (diabesity) impair kidney mitochondrial dynamics by augmenting fission and diminishing fusion, which results in mitochondrial and renal dysfunction. Based on available evidence, the antioxidant activities of melatonin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f6a5d36c451958a8ea2114cf97e342
https://hdl.handle.net/10668/3850