Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Meriem Bona"'
Publikováno v:
Journal of Pharmaceutical Sciences. 85:990-998
From the experimental n-octanol/water partition coefficients (log Poct) of 33 1,2-dithiole-3-thiones and 18 1,2-dithiol-3-ones and their respective log k, Collander-type relationships were established at various volume fractions of methanol in the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029093ab8a8582d1dedd5d2cb5d66d41
https://doi.org/10.1021/js9504088
https://doi.org/10.1021/js9504088
Publikováno v:
International Journal of Pharmaceutics. 129:295-299
First quantitative structure-activity relationships (QSAR) between electrophile detoxication properties of 1,2-dithiole-3-thiones and their log P values were checked. A very significant linear property was found with some disubstituted derivatives. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc1725b8f82974ab08bd6fa45802cb23
https://doi.org/10.1016/0378-5173(95)04260-1
https://doi.org/10.1016/0378-5173(95)04260-1
Publikováno v:
Chemical and Pharmaceutical Bulletin. 43:1894-1896
Lipophilicity of the 1, 2-dithiole-3-thione nucleus was studied by stepwise calculation of log P values of some dithiolethiones from fragmental lipophilic constants of suitable fragments composing the nucleus, and the results were compared with exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ed39758616400b8bdf593d39398a294
https://doi.org/10.1248/cpb.43.1894
https://doi.org/10.1248/cpb.43.1894
Publikováno v:
Journal of pharmaceutical sciences. 84(9)
Water/n‐octanol partition coefficients (log P) for 33 1,2‐dithiole‐3‐thiones and for 18 1,2‐dithiol‐3‐ones were determined by RP‐HPLC measurement of the concentration of the solute in aqueous solution after equilibrium. Depending on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16613614e91d7ea73cb5c345cb4acfd7
https://pubmed.ncbi.nlm.nih.gov/8537890
https://pubmed.ncbi.nlm.nih.gov/8537890