Výsledky vyhledávání - "Meriam, Haoues"

Akademický článek

Co-Administration of Anticancer Candidate MK-2206 Enhances the Efficacy of BCG Vaccine Against Mycobacterium tuberculosis in Mice and Guinea Pigs

Autor: Rania Bouzeyen, Saurabh Chugh, Tannu Priya Gosain, Mohamed-Ridha Barbouche, Meriam Haoues, Kanury V. S. Rao, Makram Essafi, Ramandeep Singh

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

The failure of M. bovis BCG to induce long-term protection has been endowed to its inability to escape the phagolysosome, leading to mild activation of CD8+ mediated T cell response. Induction of apoptosis in host cells plays an important role in pot

Externí odkaz: https://doaj.org/article/ffaa4ea1e899451aad6a467a6a8a48ab

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Akademický článek

FOXO3 Transcription Factor Regulates IL-10 Expression in Mycobacteria-Infected Macrophages, Tuning Their Polarization and the Subsequent Adaptive Immune Response

Autor: Rania Bouzeyen, Meriam Haoues, Mohamed-Ridha Barbouche, Ramandeep Singh, Makram Essafi

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Alveolar Macrophages play a key role in the development of a robust adaptive immune response against the agent of Tuberculosis (TB), Mycobacterium tuberculosis (M.tb). However, macrophage response is often hampered by the production of IL-10, a poten

Externí odkaz: https://doaj.org/article/c4dcfa8d90f24d2e8b75872409cf3572

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Akademický článek

Mertensene, a Halogenated Monoterpene, Induces G2/M Cell Cycle Arrest and Caspase Dependent Apoptosis of Human Colon Adenocarcinoma HT29 Cell Line through the Modulation of ERK-1/-2, AKT and NF-κB Signaling

Autor: Safa Tarhouni-Jabberi, Ons Zakraoui, Efstathia Ioannou, Ichrak Riahi-Chebbi, Meriam Haoues, Vassilios Roussis, Riadh Kharrat, Khadija Essafi-Benkhadir

Publikováno v: Marine Drugs, Vol 15, Iss 7, p 221 (2017)

Conventional treatment of advanced colorectal cancer is associated with tumor resistance and toxicity towards normal tissues. Therefore, development of effective anticancer therapeutic alternatives is still urgently required. Nowadays, marine seconda

Externí odkaz: https://doaj.org/article/be737c4a0df84520841f15d93398fa12

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Co-Administration of Anticancer Candidate MK-2206 Enhances the Efficacy of BCG Vaccine Against Mycobacterium tuberculosis in Mice and Guinea Pigs

Autor: Tannu Priya Gosain, Ramandeep Singh, Saurabh Chugh, Rania Bouzeyen, Mohamed-Ridha Barbouche, Meriam Haoues, Kanury V S Rao, Makram Essafi

Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2410a6ad728c222543716344d34efd3
https://www.frontiersin.org/articles/10.3389/fimmu.2021.645962/full

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Ultrasensitive detection of hazardous reactive oxygen species using flexible organic transistors with polyphenol-embedded conjugated polymer sensing layers

Autor: Mohamed Fethi Diouani, Hwajeong Kim, Youngkyoo Kim, Chulyeon Lee, Meriam Haoues, Makram Essafi, Jaehoon Jeong

Publikováno v: Journal of Hazardous Materials
Journal of Hazardous Materials, Elsevier, 2018, 355, pp.17--24. ⟨10.1016/j.jhazmat.2018.04.063⟩

International audience; Here we report that superoxide, one of the hazardous reactive oxygen species (ROS), can be quickly detected by flexible organic field-effect transistors (OFETs) with the polyphenol-embedded conjugated polymer micro-channels. R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8f4df820150a1050c2d7c548cc808a
https://doi.org/10.1016/j.jhazmat.2018.04.063

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The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells

Autor: Houcemeddine Othman, Ichrak Riahi-Chebbi, Meriam Haoues, Soumaya Souid, Makram Essafi, Habib Karoui, Alain Morel, Najet Srairi-Abid, Khadija Essafi-Benkhadir

Publikováno v: Scientific Reports
Scientific Reports, 2019, 9 (1), pp.195. ⟨10.1038/s41598-018-36808-z⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.195. ⟨10.1038/s41598-018-36808-z⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-20 (2019)
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-018-36808-z⟩

International audience; Resistance to 5-Fluorouracil chemotherapy is a major cause of therapeutic failure in colon cancer cure. Development of combined therapies constitutes an effective strategy to inhibit cancer cells and prevent the emergence of d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe4d305a6ceab17fdce5c982785b621
https://www.hal.inserm.fr/inserm-02097051

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Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression

Autor: Ammar Gasmi, Houcemeddine Othman, Makram Essafi, Renaud Grépin, Meriam Haoues, Najet Srairi-Abid, Gilles Pagès, Habib Karoui, Khadija Essafi-Benkhadir, Ons Zakraoui, Zohra Aloui, Cezary Marcinkiewicz

Publikováno v: Molecular Carcinogenesis. 56:18-35

Lebein, is an heterodimeric disintegrin isolated from Macrovipera lebetina snake venom that was previously characterized as an inhibitor of ADP-induced platelet aggregation. In this study, we investigated the effect of Lebein on the p53-dependent gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0585f28438d7476124d0d6c1804ac8fb
https://doi.org/10.1002/mc.22470

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Two distinct conformational states ofMycobacterium tuberculosisvirulent factor early secreted antigenic target 6 kDa are behind the discrepancy around its biological functions

Autor: Meriam Haoues, Mohamed-Ridha Barbouche, Arnaud Bondon, Philippe Moua, Liza Mouret, Houcemeddine Othman, Amira Refai, Najet Srairi-Abid, Makram Essafi

Publikováno v: FEBS Journal. 282:4114-4129

Early secreted antigenic target 6 kDa (ESAT-6) and culture filtrate protein 10 kDa (CFP-10) are complex proteins secreted by Mycobacterium tuberculosis that play a major role in the pathogenesis of tuberculosis. However, studies focusing on the biolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403d7ad6466a4455bf3acb6097f60c4b
https://doi.org/10.1111/febs.13408

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Helix aspersa maxima mucus exhibits antimelanogenic and antitumoral effects against melanoma cells

Autor: Jed Jebali, Manel Ben Hammouda, Chedli Ellijimi, Wassim Moslah, Naziha Marrakchi, Khadija Essafi-Benkhadir, Hazem Ben Mabrouk, Najet Srairi-Abid, Maram Morjen, Houcemeddine Othman, Meriam Haoues, José Luis

Publikováno v: Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy, 2018, 101, pp.871-880. ⟨10.1016/j.biopha.2018.03.020⟩
Biomedicine and Pharmacotherapy
Biomedicine and Pharmacotherapy, 2018, 101, pp.871-880. ⟨10.1016/j.biopha.2018.03.020⟩

International audience; Snail secretion is currently revolutionizing the world of cosmetics and human skin care. The efficacy of snail secretion in wounds healing has been proven both in vitro and by clinical studies. However, the potential anti-tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dafa67fae551648b262240a4ee117ef4
https://pubmed.ncbi.nlm.nih.gov/29635896

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Autor: Vassilios Roussis, Ons Zakraoui, Khadija Essafi-Benkhadir, Efstathia Ioannou, Safa Tarhouni-Jabberi, R. Kharrat, Ichrak Riahi-Chebbi, Meriam Haoues

Publikováno v: Marine drugs
Marine drugs, MDPI, 2017, 15 (7), ⟨10.1016/j.ccr.2008.11.003⟩
Marine drugs, MDPI, 2017, 15 (7), pp.221. ⟨10.3390/md15070221⟩
Marine Drugs, Vol 15, Iss 7, p 221 (2017)
Marine Drugs; Volume 15; Issue 7; Pages: 221
Marine Drugs

International audience; Conventional treatment of advanced colorectal cancer is associated with tumor resistance and toxicity towards normal tissues. Therefore, development of effective anticancer therapeutic alternatives is still urgently required.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bcfa744956cff79d6fcb0d24cc1c84
https://hal-riip.archives-ouvertes.fr/pasteur-01567734

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