Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Meri Uchiyama"'
Autor:
Motohiro Kato, Susumu Goyama, Nobutaka Kiyokawa, Kenichiro Hata, Kimikazu Matsumoto, Toshio Kitamura, Seishi Ogawa, Takeshi Inukai, Junko Takita, Kentaro Ohki, Masafumi Seki, Ryota Shirai, Hitomi Ueno-Yokohata, Hiroe Kizawa, Toru Uchiyama, Hiroko Ogata-Kawata, Masahiro Migita, Kazuko Hamamoto, Shohei Yamamoto, Tsukasa Hori, Hiroyuki Takahashi, Akihiro Watanabe, Daisuke Tomizawa, Masanori Yoshida, Kohji Okamura, Kazuhiko Nakabayashi, Meri Uchiyama, Moe Tamura, Shin-ichi Tsujimoto, Tomoo Osumi
Translocations of retinoic acid receptor-α (RARA), typically PML–RARA, are a genetic hallmark of acute promyelocytic leukemia (APL). However, because a small fraction of APL lack translocations of RARA, we focused here on APL cases without RARA tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a48a08deebf9face976104eb1bf03c3
https://doi.org/10.1158/0008-5472.c.6510653.v1
https://doi.org/10.1158/0008-5472.c.6510653.v1
Autor:
Motohiro Kato, Susumu Goyama, Nobutaka Kiyokawa, Kenichiro Hata, Kimikazu Matsumoto, Toshio Kitamura, Seishi Ogawa, Takeshi Inukai, Junko Takita, Kentaro Ohki, Masafumi Seki, Ryota Shirai, Hitomi Ueno-Yokohata, Hiroe Kizawa, Toru Uchiyama, Hiroko Ogata-Kawata, Masahiro Migita, Kazuko Hamamoto, Shohei Yamamoto, Tsukasa Hori, Hiroyuki Takahashi, Akihiro Watanabe, Daisuke Tomizawa, Masanori Yoshida, Kohji Okamura, Kazuhiko Nakabayashi, Meri Uchiyama, Moe Tamura, Shin-ichi Tsujimoto, Tomoo Osumi
Supplementary Methods: IRB approval, Genomic analysis, Identification of translocations and determination of their breakpoints, Plasmids Construct, Cell line and reagent, Co-immunoprecipotation and immunoblotting analysis, Luciferase assay, Retroviru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c87a9fa2073a3585c3ebb31a2e68bc2
https://doi.org/10.1158/0008-5472.22420451.v1
https://doi.org/10.1158/0008-5472.22420451.v1
Autor:
Kohji Okamura, Shinichi Tsujimoto, Daisuke Tomizawa, Tomoo Osumi, Nobutaka Kiyokawa, Akihiro Watanabe, Motohiro Kato, Kenichiro Hata, Kazuhiko Nakabayashi, Masanori Yoshida, Meri Uchiyama, Hiroyuki Takahashi
Publikováno v:
Genes, Chromosomes and Cancer. 58:820-823
Acute promyelocytic leukemia (APL) is cytogenetically characterized by the t(15;17) (q24;q21), although cases without this translocation exist. These cases are referred to as "cryptic" or "masked" translocations. Additionally, fewer than 5% of APL ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e50f12a76c76406d9cb07c630d44c5
https://doi.org/10.1002/gcc.22791
https://doi.org/10.1002/gcc.22791
Autor:
Hiroko Ogata-Kawata, Moe Tamura, Kimikazu Matsumoto, Toshio Kitamura, Nobutaka Kiyokawa, Junko Takita, Takeshi Inukai, Seishi Ogawa, Akihiro Watanabe, Toru Uchiyama, Shinichi Tsujimoto, Hitomi Ueno-Yokohata, Masahiro Migita, Hiroe Kizawa, Motohiro Kato, Ryota Shirai, Kentaro Ohki, Kohji Okamura, Daisuke Tomizawa, Tomoo Osumi, Kazuhiko Nakabayashi, Tsukasa Hori, Susumu Goyama, Hiroyuki Takahashi, Masafumi Seki, Kenichiro Hata, Meri Uchiyama, Kazuko Hamamoto, Masanori Yoshida, Shohei Yamamoto
Publikováno v:
Cancer Research. 78:4452-4458
Translocations of retinoic acid receptor-α (RARA), typically PML–RARA, are a genetic hallmark of acute promyelocytic leukemia (APL). However, because a small fraction of APL lack translocations of RARA, we focused here on APL cases without RARA tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59606bb3dbc0c8e3a880b25ff52945a2
https://doi.org/10.1158/0008-5472.can-18-0840
https://doi.org/10.1158/0008-5472.can-18-0840
Autor:
Meri Uchiyama, Tomoro Hishiki, Shinichi Tsujimoto, Keita Terashima, Dai Keino, Masahiro Sekiguchi, Yoko Shioda, Takao Deguchi, Shuichi Ito, Kentaro Ohki, Chikako Kiyotani, Daisuke Tomizawa, Hideki Ogiwara, Takako Yoshioka, Hitomi Ueno-Yokohata, Junko Takita, Tomoo Osumi, Toru Uchiyama, Kaoru Yoshida, Motohiro Kato, Kenichiro Watanabe, Nobutaka Kiyokawa, Seishi Ogawa, Masanori Yoshida, Kimikazu Matsumoto, Ryota Shirai, Hajime Okita
Publikováno v:
Neuro-Oncology
BACKGROUND Genetic hallmark of atypical teratoid/rhabdoid tumor (AT/RT) is loss-of-function variants or deletions in SMARCB1 gene on 22q11.2 chromosome, which is common to extracranial malignant rhabdoid tumors (MRT). Previous studies demonstrated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6245dafc7345836d56e5151a605c97b0
http://europepmc.org/articles/PMC7715345
http://europepmc.org/articles/PMC7715345
Autor:
Hideki Ogiwara, Masanori Yoshida, Keita Terashima, Kentaro Ohki, Shinichi Tsujimoto, Takako Yoshioka, Toru Uchiyama, Shuichi Ito, Dai Keino, Hajime Okita, Tomoo Osumi, Nobutaka Kiyokawa, Daisuke Tomizawa, Kimikazu Matsumoto, Hitomi Ueno-Yokohata, Kaoru Yoshida, Motohiro Kato, Kenichiro Watanabe, Meri Uchiyama, Tomoro Hishiki, Seishi Ogawa, Ryota Shirai, Junko Takita, Masahiro Sekiguchi, Yoko Shioda, Takao Deguchi, Chikako Kiyotani
Publikováno v:
Eur J Hum Genet
Intensive analysis of the SMARCB1 gene in malignant rhabdoid tumors (MRT) revealed eight of 16 patients with constitutional genetic variants. Three patients had mosaicism of deletion/variant of the SMARCB1 gene, which conventional methods might overl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3625f65dba25fe7e90773f439b7ea87c
https://pubmed.ncbi.nlm.nih.gov/32218533
https://pubmed.ncbi.nlm.nih.gov/32218533
Autor:
Takako Yoshioka, Meri Uchiyama, Masayuki Nakano, Masahiro Sugawa, Yoshiaki Tsutsumi, Kenichi Usami, Hideki Ogiwara, Kenichi Sakamoto, Kimikazu Matsumoto, Motohiro Kato, Keita Terashima, Takanori Mizuno, Yukihiro Matsukawa, Kyohei Isshiki, Tomoo Osumi, Yoshihiro Gocho, Daisuke Tomizawa, Shinichi Tsujimoto, Chikako Kiyotani, Yoko Shioda
Publikováno v:
Neuro-Oncology
BACKGROUND Primary diffuse leptomeningeal primitive neuroectodermal tumor (PDL PNET) is a rare embryonal brain tumor which arises primarily in the meninges without an intraparenchymal mass. Few previous reports of this condition exist, and the clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31dd52147bec5a0f1d0600121d77566c
https://doi.org/10.1093/neuonc/noaa222.215
https://doi.org/10.1093/neuonc/noaa222.215
Autor:
Tomoo, Osumi, Shin-Ichi, Tsujimoto, Moe, Tamura, Meri, Uchiyama, Kazuhiko, Nakabayashi, Kohji, Okamura, Masanori, Yoshida, Daisuke, Tomizawa, Akihiro, Watanabe, Hiroyuki, Takahashi, Tsukasa, Hori, Shohei, Yamamoto, Kazuko, Hamamoto, Masahiro, Migita, Hiroko, Ogata-Kawata, Toru, Uchiyama, Hiroe, Kizawa, Hitomi, Ueno-Yokohata, Ryota, Shirai, Masafumi, Seki, Kentaro, Ohki, Junko, Takita, Takeshi, Inukai, Seishi, Ogawa, Toshio, Kitamura, Kimikazu, Matsumoto, Kenichiro, Hata, Nobutaka, Kiyokawa, Susumu, Goyama, Motohiro, Kato
Publikováno v:
Cancer research. 78(16)
Translocations of retinoic acid receptor-α (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08d66dc7b4604c2c068ad9c1e4fa0eb2
https://pubmed.ncbi.nlm.nih.gov/29921692
https://pubmed.ncbi.nlm.nih.gov/29921692
Autor:
Junko Takita, Masahiro Sekiguchi, Etsuro Ito, Toru Uchiyama, Kiminori Terui, Yuki Arakawa, Yuji Yamada, Masanori Yoshida, Takaya Moriyama, Jun J. Yang, Shuichi Ito, Atsushi Manabe, Daisuke Tomizawa, Rina Nishii, Tomoo Osumi, Meri Uchiyama, Shinichi Tsujimoto, Motohiro Kato, Nobutaka Kiyokawa, Katsuyoshi Koh, Ko Kudo, Ryota Shirai
Publikováno v:
Leukemia. 32(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af86c0a166b14089f76bcf794adb6a02
https://pubmed.ncbi.nlm.nih.gov/29967377
https://pubmed.ncbi.nlm.nih.gov/29967377
Autor:
Satoru Kumaki, Ikuko Hakozaki, Yoji Sasahara, Chung Yeng Looi, Meri Uchiyama, Yuko Watanabe, Miki Satoh, Shigeo Kure, Wei Du, Shigeru Tsuchiya, Won Fen Wong, Toru Uchiyama
Publikováno v:
International Immunology. 26:341-352
Mutations in the gene encoding the Wiskott–Aldrich syndrome protein (WASP) are responsible for Wiskott–Aldrich syndrome and WASP is a major actin regulator in the cytoplasm. Although rare gain-of-function mutations in the WASP gene are known to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8917eeec5fd4c20c4278d1dd03daf444
https://doi.org/10.1093/intimm/dxt072
https://doi.org/10.1093/intimm/dxt072