Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Meri T. Firpo"'
Autor:
Samuel A. Einstein, Leah V. Steyn, Bradley P. Weegman, Thomas M. Suszynski, Athanassios Sambanis, Timothy D. O’Brien, Efstathios S. Avgoustiniatos, Meri T. Firpo, Melanie L. Graham, Jody Janecek, Lynn E. Eberly, Michael Garwood, Charles W. Putnam, Klearchos K. Papas
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
IntroductionSubcutaneous macroencapsulation devices circumvent disadvantages of intraportal islet therapy. However, a curative dose of islets within reasonably sized devices requires dense cell packing. We measured internal PO2 of implanted devices,
Externí odkaz:
https://doaj.org/article/4d2c40b1f118487788b0c8b74419747e
Autor:
Eihachiro Kawase, Qi Zhou, Stephen R. Sullivan, Jeremy M. Crook, Glyn Stacey, Tenneille Ludwig, Jennifer Man, Nissim Benvenisty, Steve Oh, Marc L Turner, Shin Kawamata, Andreas Kurtz, Patricia Pranke, Peter W. Harrison, Jeanne F. Loring, Lygia da Veiga Pereira, Catharina Brandsten, Meri T. Firpo, Alex Alderton, Michael Sheldon, Rachel Steeg, Joanne C. Mountford, Michael B. Yaffe, Jung-Hyun Kim
Publikováno v:
Stem Cells (Dayton, Ohio)
STEM CELLS
STEM CELLS
This report summarizes the recent activity of the International Stem Cell Banking Initiative held at Harvard Stem Cell Institute, Boston, MA, USA, on June 18, 2017. In this meeting, we aimed to find consensus on ongoing issues of quality control (QC)
Autor:
Bradley P Weegman, Peter Nash, Alexandra L Carlson, Kristin J Voltzke, Zhaohui Geng, Marjan Jahani, Benjamin B Becker, Klearchos K Papas, Meri T Firpo
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76611 (2013)
Cellular therapies are emerging as a standard approach for the treatment of several diseases. However, realizing the promise of cellular therapies across the full range of treatable disorders will require large-scale, controlled, reproducible culture
Externí odkaz:
https://doaj.org/article/50b22b32b86345aebb567d060b9e1a42
Publikováno v:
Tissue Engineering Part C: Methods. 22:1009-1017
Techniques to monitor the oxygen partial pressure (pO2) within implanted tissue-engineered grafts (TEGs) are critically necessary for TEG development, but current methods are invasive and inaccurate. In this study, we developed an accurate and noninv
Publikováno v:
Stem Cell Research, Vol 15, Iss 3, Pp 469-480 (2015)
Leukemia inhibitory factor (LIF) is widely used to establish and maintain naïve pluripotent stem cells, including mouse embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Although the combination of chemical inhibitors called 2i
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1590
Embryonic stem cells (ESCs) represent a mainstay for pluripotent stem cell research and development (RD) and provide tangible opportunities for clinical translation including cell therapies and drug discovery. Moreover, in spite of the discovery of i
Autor:
Andreas Kurtz, Martin F. Pera, Tsuneo Takahashi, Nafees Rahman, Ruttachuk Rungsiwiwut, Michael Sheldon, Qi Zhou, Jung-Hyun Kim, Jeremy M. Crook, Thomas Novak, Laura Clarke, Geoffrey P. Lomax, Steve Oh, Tohru Masui, Jeanne F. Loring, Orla O'Shea, Fanyi Zeng, Wataru Fujibuchi, Tenneille Ludwig, Maneesha S. Inamdar, Shin Kawamata, Meri T. Firpo, Patricia Pranke, Rosario Isasi, Bao-Zhu Yuan, Ji-Hyeon Ju, Glyn Stacey, Soo Kyung Koo
Publikováno v:
STEM CELLS Translational Medicine
Stem Cells Translational Medicine
Stem Cells Translational Medicine
This article summarizes the recent activity of the International Stem Cell Banking Initiative (ISCBI) held at the California Institute for Regenerative Medicine (CIRM) in California (June 26, 2016) and the Korean National Institutes for Health in Kor
Spheroid Culture for Enhanced Differentiation of Human Embryonic Stem Cells to Hepatocyte-Like Cells
Autor:
Ravali Raju, Wei Shou Hu, Derek Jason Owens, Meri T. Firpo, Kartik Subramanian, Timothy O'Brien, Catherine M. Verfaillie
Publikováno v:
Stem Cells and Development. 23:124-131
Stem cell-derived hepatocyte-like cells hold great potential for the treatment of liver disease and for drug toxicity screening. The success of these applications hinges on the generation of differentiated cells with high liver specific activities. M
Publikováno v:
Stem Cell Research, Vol 15, Iss 2, Pp 384-386 (2015)
It has been very difficult, if not impossible, to establish mouse induced pluripotent stem cells (iPSCs) from differentiated cells, such as fibroblasts, without leukemia inhibitory factor (LIF). We have established and maintained LIF-independent iPSC
Autor:
Peter Nash, Meri T. Firpo, Ahmad Essawy, Kristin J. Voltzke, Klearchos K. Papas, Bradley P. Weegman, Marjan Jahani, Zhaohui Geng, Alexandra L. Carlson, Benjamin B. Becker
Publikováno v:
Journal of Visualized Experiments.
In this demonstration, spheroids formed from the β-TC6 insulinoma cell line were cultured as a model of manufacturing a mammalian islet cell product to demonstrate how regulating nutrient levels can improve cell yields. In previous studies, bioreact