Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Meri Slavica"'
Autor:
Pal L. Vaghy, B.A. Smith, Meri Slavica, Duane D. Miller, J. De Los Angeles, Longping Lei, Dennis R. Feller
Publikováno v:
Journal of Cardiovascular Pharmacology. 31:721-733
Studies have investigated the pharmacologic mechanism of 2-(4'-isothiocyanatobenzyl) imidazoline (IBI) and analogs for interaction with imidazoline receptors (IRs), alpha-adrenergic receptors (alpha-ARs), and calcium channels in cardiovascular muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976d682f284bd22c1f1b5e1dabdae29f
https://doi.org/10.1097/00005344-199805000-00011
https://doi.org/10.1097/00005344-199805000-00011
Autor:
Guoping Sun, John C. Miller, G. Shams, Lane J. Wallace, Norman J. Uretsky, Meri Slavica, David M. Weinstein, Duane D. Miller
Publikováno v:
Journal of Medicinal Chemistry. 41:1034-1041
The R- and S-isomers of 3,5-dinitro-o-tyrosine (6a,b) have been synthesized through the use of chemoenzymatic synthesis and shown to bind differentially with the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid (AMPA, 3) receptors. The phenol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e1aa590c72b3cfef4638f26dc7f8b3
https://doi.org/10.1021/jm970276q
https://doi.org/10.1021/jm970276q
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7374fe492890e57ca5a87e1b0ee9fb74
https://doi.org/10.1002/chin.199444139
https://doi.org/10.1002/chin.199444139
Autor:
Qian Wu, Michael J. McLeish, Gary L. Grunewald, Joanne M. Caine, Meri Slavica, Stuart A. Thomson
Inhibitors of phenylethanolamine N-methyltransferase [PNMT, the enzyme that catalyzes the final step in the biosynthesis of epinephrine (Epi)] may be of use in determining the role of Epi in the central nervous system. Here we describe the synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647843d054d9d9fae5bd9726e67b90b5
https://europepmc.org/articles/PMC2696812/
https://europepmc.org/articles/PMC2696812/
Autor:
Ronald T. Borchardt, Gary L. Grunewald, Kevin R. Criscione, Meri Slavica, Wen Wang, Qifang Li, Timothy M. Caldwell
Publikováno v:
Journal of medicinal chemistry. 42(18)
A series of 3-fluoromethyl-1,2,3,4-tetrahydroisoquinolines (3-fluoromethyl-THIQs) was proposed, and their phenylethanolamine N-methyltransferase (PNMT) and alpha(2)-adrenoceptor affinities were predicted through the use of comparative molecular field
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f696963aa4023e243dfc6984db4c90
https://pubmed.ncbi.nlm.nih.gov/10479290
https://pubmed.ncbi.nlm.nih.gov/10479290
Publikováno v:
Journal of medicinal chemistry. 37(12)
IBI [2-(4'-isothiocyanatobenzyl)imidazoline, 3] has been shown to cause slow-onset, long-lasting contractions of rat thoracic aorta through a non-alpha-adrenergic receptor (non-alpha-AR) mediated mechanism. A series of IBI-related anlogs 7-14 and 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bb7dee0ac15d3261b18ace93d1cee4
https://pubmed.ncbi.nlm.nih.gov/8021927
https://pubmed.ncbi.nlm.nih.gov/8021927