Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Meri Firpo"'
Publikováno v:
Stem Cell Research, Vol 15, Iss 3, Pp 469-480 (2015)
Leukemia inhibitory factor (LIF) is widely used to establish and maintain naïve pluripotent stem cells, including mouse embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Although the combination of chemical inhibitors called 2i
Externí odkaz:
https://doaj.org/article/a385cf2cc2a54b3f86c894ef67675b80
Publikováno v:
Stem Cell Research, Vol 15, Iss 2, Pp 384-386 (2015)
It has been very difficult, if not impossible, to establish mouse induced pluripotent stem cells (iPSCs) from differentiated cells, such as fibroblasts, without leukemia inhibitory factor (LIF). We have established and maintained LIF-independent iPSC
Externí odkaz:
https://doaj.org/article/bc046d0bee7046398db2b3d33595260b
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34149 (2012)
A major difficulty of producing induced pluripotent stem cells (iPSCs) has been the low efficiency of reprogramming differentiated cells into pluripotent cells. We previously showed that 5% of mouse embryonic fibroblasts (MEFs) were reprogrammed into
Externí odkaz:
https://doaj.org/article/58d0648dfcbe415892e0d31b345fb6ae
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39022 (2012)
Human induced pluripotent stem cells (iPSCs) can be divided into a leukemia inhibitory factor (LIF)-dependent naïve type and a basic fibroblast growth factor (bFGF)-dependent primed type. Although the former are more undifferentiated than the latter
Externí odkaz:
https://doaj.org/article/00a4ff5e4afb4a6ba7afdac262b67811
Autor:
Philip Roelandt, Karen Ann Pauwelyn, Pau Sancho-Bru, Kartik Subramanian, Bipasha Bose, Laura Ordovas, Kim Vanuytsel, Martine Geraerts, Meri Firpo, Rita De Vos, Johan Fevery, Frederik Nevens, Wei-Shou Hu, Catherine M Verfaillie
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12101 (2010)
Stem cell-derived hepatocytes may be an alternative cell source to treat liver diseases or to be used for pharmacological purposes. We developed a protocol that mimics mammalian liver development, to differentiate cells with pluripotent characteristi
Externí odkaz:
https://doaj.org/article/5036bf44a9f94b0ca7c4b1e2c912edd1
Autor:
Meri, Firpo, John, Wagner
Publikováno v:
Minnesota medicine. 94(5)
Autor:
Meri, Firpo, Nobuaki K, Kikyo
Publikováno v:
Minnesota medicine. 90(5)
Stem cell research holds promise for new treatments for diseases such as Parkinson's and injuries such as those to the spinal cord. Yet stem cell research remains steeped in controversy. This article defines key terms and outlines some of the basic c