Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Meri, Kaustio"'
Autor:
Miia Perälä, Meri Kaustio, Alexander Salava, Eveliina Jakkula, Anna S. Pelkonen, Janna Saarela, Anita Remitz, Mika J. Mäkelä
Publikováno v:
JID Innovations, Vol 3, Iss 4, Pp 100203- (2023)
Early-onset, persistent atopic dermatitis (AD) is proposed as a distinct subgroup that may have specific genotypic features. FLG gene loss-of-function variants are the best known genetic factors contributing to epidermal barrier impairment and eczema
Externí odkaz:
https://doaj.org/article/ec37ca17973a4ca79b1527272d1e6353
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230819 (2020)
STAT3 mediates signalling downstream of cytokine and growth factor receptors where it acts as a transcription factor for its target genes, including oncogenes and cell survival regulating genes. STAT3 has been found to be persistently activated in ma
Externí odkaz:
https://doaj.org/article/f4e1fb44dd3548b2a5331ee6a4b73ca5
Autor:
Elina A. Tuovinen, Outi Kuismin, Leila Soikkonen, Timi Martelius, Meri Kaustio, Sari Hämäläinen, Hanna Viskari, Jaana Syrjänen, Ulla Wartiovaara-Kautto, Kari K. Eklund, Janna Saarela, Markku Varjosalo, Juha Kere, Timo Hautala, Mikko R.J. Seppänen
Publisher Copyright: © 2022 The Authors Nuclear factor κ light-chain enhancer of activated B cells (NF-κB) family of evolutionarily conserved transcription factors are involved in key cellular signaling pathways. Previously, hypogammaglobulinemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5d589bf29376b68540b34e38b32b5c
https://trepo.tuni.fi/handle/10024/145528
https://trepo.tuni.fi/handle/10024/145528
Autor:
Wenny Santaniemi, Pirjo Åström, Virpi Glumoff, Nora Pernaa, Ella-Noora Tallgren, Sanna Palosaari, Antti Nissinen, Meri Kaustio, Outi Kuismin, Janna Saarela, Katariina Nurmi, Kari K. Eklund, Mikko R. J. Seppänen, Timo Hautala
Loss-of-function (LOF) mutations in NFKB1, coding for p105, may cause common variable immunodeficiency due to dysregulation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κΒ) pathway. Monoallelic LOF variants of NFKB1 can pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2482defdbbc9bfe21e6acdaa969094e6
http://urn.fi/urn:nbn:fi-fe2023052648387
http://urn.fi/urn:nbn:fi-fe2023052648387
Autor:
Iivo, Hetemäki, Meri, Kaustio, Matias, Kinnunen, Nelli, Heikkilä, Salla, Keskitalo, Kirsten, Nowlan, Simo, Miettinen, Joona, Sarkkinen, Virpi, Glumoff, Noora, Andersson, Kaisa, Kettunen, Reetta, Vanhanen, Katariina, Nurmi, Kari K, Eklund, Johannes, Dunkel, Mikko I, Mäyränpää, Heinrich, Schlums, T Petteri, Arstila, Kai, Kisand, Yenan T, Bryceson, Pärt, Peterson, Ulla, Otava, Jaana, Syrjänen, Janna, Saarela, Markku, Varjosalo, Eliisa, Kekäläinen
Publikováno v:
Science immunology. 6(65)
The Ikaros family transcription factors regulate lymphocyte development. Loss-of-function variants in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::653382fc70b384af21c884f81f1d52d3
https://pubmed.ncbi.nlm.nih.gov/34826260
https://pubmed.ncbi.nlm.nih.gov/34826260
Autor:
Jaana Syrjänen, Heinrich Schlums, Yenan T. Bryceson, Iivo Hetemäki, Salla Keskitalo, Meri Kaustio, Noora Andersson, Nelli Heikkilä, Kari K. Eklund, Virpi Glumoff, Matias Kinnunen, Mikko I. Mäyränpää, Simo Miettinen, T. Petteri Arstila, Joona Sarkkinen, Kai Kisand, Johannes Dunkel, Reetta Vanhanen, Katariina Nurmi, Ulla Otava, Eliisa Kekäläinen, Kaisa Kettunen, Markku Varjosalo, Janna Saarela, Pärt Peterson
The IKAROS family transcription factors regulate lymphocyte development. Loss-of-function variants in IKZF1 cause primary immunodeficiency, but IKAROS family members IKZF2 and IKZF3 have not yet been associated with immunodeficiency yet. Here, we des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de462bc93bc0f7f14249247ed95d486b
https://doi.org/10.1101/2021.08.25.21262015
https://doi.org/10.1101/2021.08.25.21262015
Autor:
Leena-Maija Vanha-Aho, Anni Kleino, Meri Kaustio, Johanna Ulvila, Bettina Wilke, Dan Hultmark, Susanna Valanne, Mika Rämet
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37153 (2012)
Drosophila is a well-established model organism for studying innate immunity because of its high resistance against microbial infections and lack of adaptive immunity. In addition, the immune signaling cascades found in Drosophila are evolutionarily
Externí odkaz:
https://doaj.org/article/d7ecac3ea86f4f1ba47dc384a68bdb63
Autor:
Sari Hämäläinen, Mikko Seppänen, Maija Lepistö, Aarno Palotie, Kimmo Porkka, Timo Hautala, Henrikki Almusa, Hanna Viskari, Luca Trotta, Jaana Syrjänen, Meri Kaustio, Janna Saarela
Publikováno v:
European Journal of Human Genetics
Antibody class-switch recombination and somatic hypermutation critically depend on the function of activation-induced cytidine deaminase (AID). Rare variants in its gene AICDA have been reported to cause autosomal recessive AID deficiency (autosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502aac35609309d4084f4c155592d539
http://europepmc.org/articles/PMC5027683
http://europepmc.org/articles/PMC5027683
Autor:
Emma I. Andersson, Satu Mustjoki, Timo Siitonen, Terhi Tapiainen, Mervi Taskinen, Janna Saarela, Mikko Seppänen, Sari Hämäläinen, Timo Hautala, Hanna Juntti, Riikka Keski-Filppula, Andrey Zavialov, Meri Kaustio, Timi Martelius, Luca Trotta, Michael S. Hershfield, Mette Ilander
Publikováno v:
Journal of Allergy and Clinical Immunology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770281a09500bca8af3a877db04ca8cc
https://pubmed.ncbi.nlm.nih.gov/29391253
https://pubmed.ncbi.nlm.nih.gov/29391253
Publikováno v:
JAMA Dermatology. 155:863
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e0dbbd81c562d4242594424d1ad59c
https://doi.org/10.1001/jamadermatol.2019.1201
https://doi.org/10.1001/jamadermatol.2019.1201