Early tumor regrowth is a contributor to impaired survival in patients with completely resected advanced ovarian cancer. An exploratory analysis of the Intergroup trial AGO-OVAR 12

Autor: Heitz, F., Harter, P., Åvall-Lundqvist, E., Reuss, A., Pautier, P., Cormio, G., Colombo, N., Reinthaller, A., Vergote, I., Poveda, A., Ottevanger, P.B., Hanker, L.C., Leminen, A., Alexandre, J., Canzler, U., Sehouli, J., Herrstedt, J., Fiane, B., Merger, M., du Bois, A.

Publikováno v: In Gynecologic Oncology February 2019 152(2):235-242

Standard first-line chemotherapy with or without nintedanib for advanced ovarian cancer (AGO-OVAR 12): a randomised, double-blind, placebo-controlled phase 3 trial

Autor: du Bois, A, Kristensen, G, Ray-Coquard, I, Reuss, A, Pignata, S, Colombo, N, Denison, U, Vergote, I, Del Campo JM, Ottevanger, P, Heubner, M, Minarik, T, Sevin, E, de Gregorio, N, Bidziński, M, Pfisterer, J, Malander, S, Hilpert, F, Mirza, Mr, Scambia, G, Meier, W, Nicoletto, Mo, Bjørge, L, Lortholary, A, Sailer, Mo, Merger, M, Harter, P, AGO Study Group led Gynecologic Cancer Intergroup/European Network of Gynaecologic Oncology Trials Groups Intergroup Consortium: Università degli Studi di Torino ITA, Ferrero, A, Et, Al

Publikováno v: Lancet Oncology, 17, 1, pp. 78-89
du Bois, A, Kristensen, G, Ray-Coquard, I, Reuss, A, Pignata, S, Colombo, N, Denison, U, Vergote, I, Del Campo, J M, Ottevanger, P, Heubner, M, Minarik, T, Sevin, E, de Gregorio, N, Bidziński, M, Pfisterer, J, Malander, S, Hilpert, F, Mirza, M R, Scambia, G, Meier, W, Nicoletto, M O, Bjørge, L, Lortholary, A, Sailer, M O, Merger, M, Harter, P & AGO Study Group led Gynecologic Cancer Intergroup/European Network of Gynaecologic Oncology Trials Groups Intergroup Consortium 2016, ' Standard first-line chemotherapy with or without nintedanib for advanced ovarian cancer (AGO-OVAR 12) : a randomised, double-blind, placebo-controlled phase 3 trial ', Lancet Oncology, vol. 17, no. 1, pp. 78-89 . https://doi.org/10.1016/S1470-2045(15)00366-6
Lancet Oncology, 17, 78-89

BACKGROUND: Angiogenesis is a target in the treatment of ovarian cancer. Nintedanib, an oral triple angiokinase inhibitor of VEGF receptor, platelet-derived growth factor receptor, and fibroblast growth factor receptor, has shown activity in phase 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978a413fe8167ddba627ac3f70a6cc68
https://doi.org/10.1016/s1470-2045(15)00366-6

AGO-OVAR 12 : A Randomized Placebo-controlled GCIG/ENGOT-Intergroup Phase III trial of standard frontline chemotherapy plus /- Nintedanib for advanced ovarian cancer

Autor: Harter, P., Kimmig, Rainer, de Gregorio, N., Reuss, A., Pfisterer, J., Cibula, D., Hilpert, F., Meier, W., Hanker, L. C., Canzler, U., Sehouli, J., Baumann, K., Burges, A., Gropp-Meier, M., Hasenburg, A., Belau, A., Fehm, T., Kosse, J., Mahner, S., Schmalfeldt, B., Marme, F., Richter, B., Herwig, U., Liebrich, C., Gerber, B., Potenberg, J., Krabisch, P., Thill, M., Merger, M., du Bois, A.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=unidue___bib::1bb2725b3769f591ad7ccd4c592f5cca

Exogram - niveau intermédiaire

Autor: Sini, Lorella, Merger, M. F.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3728::3ff9632706bfdc24a4e03a465c79213f
http://hdl.handle.net/11568/98948

Un contratto regale, da Savoia Carignano a Savoia

Autor: Nigro, G., Mori, G., Segreto, L., Agnoletti, M., Barucci, P., Berini, F., Bibikov, M., Borelli, G., Cassandro, M., Cattini, M., Fanfani, T., Di Vittorio, A., Farolfi, B., Fenicia, G., Fenoaltea, S., Filippini, J. P., Finzi, R., Giura, V., Guenzi, A., Hertner, P., Ladero Quesnada, M. A., Livi Bacci, M., Lopez Nadai, G., Massa, P., Merger, M., Moioli, A., Nadal, J., O' Brien, P., Orlandi, A., Pecorari, P., Rollandi, M. S., Picco, Leila, Rotelli, C., Samsonowicz, H., Spallanzani, M., Stumpo, E., Vigo, G., Zalin, G., Zilli, I.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______970::970ad262b7f8a49d0c9f7ea02ee56582
http://hdl.handle.net/2318/101957