Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Merema, M.T"'
Autor:
De Kanter, R a, Olinga, P a, De Jager, M.H a, Merema, M.T a, Meijer, D.K.F a, Groothius, G.M.M a, *
Publikováno v:
In Toxicology in Vitro 1999 13(4):737-744
Autor:
Olinga, Peter, Hoeven, Joost Alexander Boreas van der, Merema, M.T., Freund, R.L., Ploeg, R.J, Groothuis, Geny
Publikováno v:
Liver International, 25(1), 109-116. Wiley
BACKGROUND: In this study, we investigated the influence of brain death on inflammatory response and the effects of brain death on liver function both directly after explantation and after reoxygenation. METHODS: The influence of brain death on liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5a85275bc0a59c7f630c6dde41ae2598
https://ora.ox.ac.uk/objects/uuid:f317103a-9353-4b65-9c4d-c2e41cb29e79
https://ora.ox.ac.uk/objects/uuid:f317103a-9353-4b65-9c4d-c2e41cb29e79
Publikováno v:
Toxicology in Vitro, 1, 30, 288-299
Precision-cut liver slices (PCLS) are an ex vivo model for metabolism and toxicity studies. However, data on the maintenance of the morphological integrity of the various cell types in the slices during prolonged incubation are lacking. Therefore, ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ea3582891b30a7458c8bc8b077f1ab00
http://resolver.tudelft.nl/uuid:d5030cfa-80a1-492d-bf62-89c6c47ee55b
http://resolver.tudelft.nl/uuid:d5030cfa-80a1-492d-bf62-89c6c47ee55b
Autor:
Verpoorte, E., Oomen, P.E., Skolimowski, M.D., Mulder, P.P.M.F.A., van Midwoud, P.M., Starokozhko, V., Merema, M.T., Molema, G., Groothuis, G.M.M.
Publikováno v:
2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators & Microsystems (TRANSDUCERS); 2015, p224-227, 4p
Autor:
Olinga, P, Hof, IH, Smit, M, de Jager, MH, Swart, PJ, Slooff, MJH, Meijer, DKF, Groothuis, GMM, Merema, M.T.
Publikováno v:
Journal of Pharmacological and Toxicological Methods, 45(1), 55-63
In the present study we investigated the applicability of the liver slice model to study mechanisms of drug uptake. Four model compounds were investigated that enter hepatocytes via entirely different membrane transport mechanisms. Rhodamine B (RB),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::dc7560045ec96c12ecc4ac89d72e0b6b
https://research.rug.nl/en/publications/a0d631ab-1b09-4573-a3cb-054934919e61
https://research.rug.nl/en/publications/a0d631ab-1b09-4573-a3cb-054934919e61
Publikováno v:
Liver, 20(5), 374-380
Aims/Background: In liver transplantation, adequate function tests for donor livers and transplanted livers are of utmost importance to provide an objective basis for decision-making. Isolated hepatocyte and/or slice preparations from human donor liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::732f3b4a3745a4685f04e8cc59b958bf
https://research.rug.nl/en/publications/dfd08fdf-79e4-482b-81d8-40e4b7cd5f6e
https://research.rug.nl/en/publications/dfd08fdf-79e4-482b-81d8-40e4b7cd5f6e
Publikováno v:
Journal of Hepatology, 21(3), 308-314. ELSEVIER SCIENCE BV
The effect of ethanol on the hepatic uptake of various cationic drugs was studied in isolated perfused rat livers, isolated rat hepatocytes and isolated rat liver mitochondria. In isolated rat hepatocytes and in isolated perfused rat livers, the upta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::449c27e80241e2bdfdacbb89d13d797e
https://research.rug.nl/en/publications/174dc0d5-4f2d-4f5a-a7e1-77c647b44b8f
https://research.rug.nl/en/publications/174dc0d5-4f2d-4f5a-a7e1-77c647b44b8f
Autor:
OLINGA, P, MEIJER, DKF, SLOOFF, MJH, GROOTHUIS, GMM, Merema, M.T., Crommelin, D, Couvreur, P, Duchene, D
Publikováno v:
IN VITRO AND EX VIVO TEST SYSTEMS TO RATIONALIZE DRUG DESIGN AND DELIVERY, 204-208
STARTPAGE=204;ENDPAGE=208;TITLE=IN VITRO AND EX VIVO TEST SYSTEMS TO RATIONALIZE DRUG DESIGN AND DELIVERY
STARTPAGE=204;ENDPAGE=208;TITLE=IN VITRO AND EX VIVO TEST SYSTEMS TO RATIONALIZE DRUG DESIGN AND DELIVERY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::37f40e10d9cb3aa6ce54a2531ebf2558
https://research.rug.nl/en/publications/d7e1c6b4-62e6-4ce5-b574-5d151a3775cc
https://research.rug.nl/en/publications/d7e1c6b4-62e6-4ce5-b574-5d151a3775cc
Autor:
GROOTHUIS, GMM, OLINGA, P, SANDKER, GW, SLOOFF, MJH, MEIJER, DKF, Merema, M.T., Crommelin, D, Couvreur, P, Duchene, D
Publikováno v:
IN VITRO AND EX VIVO TEST SYSTEMS TO RATIONALIZE DRUG DESIGN AND DELIVERY, 199-203
STARTPAGE=199;ENDPAGE=203;TITLE=IN VITRO AND EX VIVO TEST SYSTEMS TO RATIONALIZE DRUG DESIGN AND DELIVERY
STARTPAGE=199;ENDPAGE=203;TITLE=IN VITRO AND EX VIVO TEST SYSTEMS TO RATIONALIZE DRUG DESIGN AND DELIVERY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::cdad9236dfe5b060de2e3d705057f201
https://research.rug.nl/en/publications/6ecad859-d135-4c93-81cd-27f9906d9e3f
https://research.rug.nl/en/publications/6ecad859-d135-4c93-81cd-27f9906d9e3f
Publikováno v:
Biochemical Pharmacology, 46(11), 2093-2096. PERGAMON-ELSEVIER SCIENCE LTD
Rat hepatocytes were preserved for 24hr with high recovery and good maintenance of viability and transport function both in University of Wisconsin (UW) solution and in various simplified UW solutions. Cell quality is somewhat affected after 48 hr of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::ac1173b78e7201540afc49e9d31b1bcf
https://research.rug.nl/en/publications/2e8c08cf-4c99-4953-8608-29a81c7288b3
https://research.rug.nl/en/publications/2e8c08cf-4c99-4953-8608-29a81c7288b3