Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Merel Oeyen"'
Publikováno v:
Biosensors, Vol 14, Iss 8, p 362 (2024)
Orthoflaviviruses cause a major threat to global public health, and no antiviral treatment is available yet. Zika virus (ZIKV) entry, together with many other viruses, is known to be enhanced by phosphatidylserine (PS) receptors such as T-cell immuno
Externí odkaz:
https://doaj.org/article/db8590e2b8b44b2aa0598dee967d1205
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors
Autor:
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdewijn, Dominique Schols, Peng Zhan, Xinyong Liu
Publikováno v:
Molecules, Vol 28, Iss 1, p 160 (2022)
The Coronavirus Disease 2019 (COVID-19) and dengue fever (DF) pandemics both remain to be significant public health concerns in the foreseeable future. Anti-SARS-CoV-2 drugs and vaccines are both indispensable to eliminate the epidemic situation. Her
Externí odkaz:
https://doaj.org/article/89b6753f327840d6a40932bf3754e640
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176057 (2017)
The chemokine receptor CXCR4 is activated by its unique chemokine ligand CXCL12 and regulates many physiological and developmental processes such as hematopoietic cell trafficking. CXCR4 is also one of the main co-receptors for human immunodeficiency
Externí odkaz:
https://doaj.org/article/067dc6d6fda34c54b7973fd8dcd2b1e4
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors
Autor:
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdewijn, Dominique Schols, Peng Zhan, Xinyong Liu
Publikováno v:
Molecules; Volume 28; Issue 1; Pages: 160
The Coronavirus Disease 2019 (COVID-19) and dengue fever (DF) pandemics both remain to be significant public health concerns in the foreseeable future. Anti-SARS-CoV-2 drugs and vaccines are both indispensable to eliminate the epidemic situation. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dab3f9b3c3f2ed8cbf75985fbb973cc
https://lirias.kuleuven.be/handle/20.500.12942/711110
https://lirias.kuleuven.be/handle/20.500.12942/711110
Autor:
Dominique Schols, Eef Meyen, Sam Noppen, Merel Oeyen, Sandra Claes, Jordi Doijen, Roderich D. Süssmuth, Kurt Vermeire
Publikováno v:
Virology. 562:74-86
To date, there are no broad-spectrum antivirals available to treat infections with flaviviruses such as dengue (DENV) and Zika virus (ZIKV). In this study, we determine the broad antiviral activity of the lantibiotic Labyrinthopeptin A1. We show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c74bcc368f25789d81cf7d623784477
https://doi.org/10.1016/j.virol.2021.07.003
https://doi.org/10.1016/j.virol.2021.07.003
In this study, we use electric cell-substrate impedance sensing (ECIS), an established cell-based electrical impedance (CEI) technology, to decipher the kinetic cytopathic effect (CPE) induced by Zika virus (ZIKV) in susceptible human A549 lung epith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f33391e818062c22470eb18282f4c2a
https://lirias.kuleuven.be/handle/20.500.12942/703386
https://lirias.kuleuven.be/handle/20.500.12942/703386
Autor:
Merel Oeyen, N.V. Suryanarayana Birudukota, Andrea Kröger, Sven-Kevin Hotop, Sibylle Haid, Javier Martínez, Janine Schreiber, Joachim Wink, Martin Messerle, Thomas F. Schulz, Roderich D. Süssmuth, Sebastian Blockus, Dominique Schols, Thomas Pietschmann, Andreas Meyerhans, Hans Prochnow, Christine Goffinet, Philipp Klahn, Kathrin I. Mohr, Sergej Franz, Katharina Rox, Mark Brönstrup, Dominic H. Banda, Loreen Weichert
Publikováno v:
J Virol
Recercat. Dipósit de la Recerca de Catalunya
instname
Journal of virology
Recercat. Dipósit de la Recerca de Catalunya
instname
Journal of virology
To counteract the serious health threat posed by known and novel viral pathogens, drugs that target a variety of viruses through a common mechanism have attracted recent attention due to their potential in treating (re-)emerging infections, for which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b26277075bd72b945800fdc6b8e167
https://doi.org/10.1128/jvi.01471-19
https://doi.org/10.1128/jvi.01471-19
Autor:
Kurt Vermeire, Sandra Claes, Bernt O. Myrvold, Dominique Schols, Merel Oeyen, Sam Noppen, Emiel Vanhulle
Publikováno v:
Virus Research. 274:197760
In Gordts et al. (2015), we have shown that lignosulfonic acid, a commercially available lignin derivative, possesses broad antiviral activity against human immunodeficiency virus (HIV) and Herpes simplex virus (HSV) by preventing viral entry into su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f2faa8fc25fcc7b0ec95e1b67ff409
https://doi.org/10.1016/j.virusres.2019.197760
https://doi.org/10.1016/j.virusres.2019.197760
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 4, p e0176057 (2017)
PLoS ONE, Vol 12, Iss 4, p e0176057 (2017)
The chemokine receptor CXCR4 is activated by its unique chemokine ligand CXCL12 and regulates many physiological and developmental processes such as hematopoietic cell trafficking. CXCR4 is also one of the main co-receptors for human immunodeficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0159cdb71247664eaff1471b307eb0b5
https://lirias.kuleuven.be/handle/123456789/580457
https://lirias.kuleuven.be/handle/123456789/580457