Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Merel J W Adjobo‐Hermans"'
Autor:
Marieke Mastop, Nathalie R Reinhard, Cristiane R Zuconelli, Fenna Terwey, Theodorus W J Gadella, Jakobus van Unen, Merel J W Adjobo-Hermans, Joachim Goedhart
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195649 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0193705.].
Externí odkaz:
https://doaj.org/article/0b005f688a0b4cbe86761776992737de
Autor:
Marieke Mastop, Nathalie R Reinhard, Cristiane R Zuconelli, Fenna Terwey, Theodorus W J Gadella, Jakobus van Unen, Merel J W Adjobo-Hermans, Joachim Goedhart
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193705 (2018)
Förster Resonance Energy Transfer (FRET) provides a way to directly observe the activation of heterotrimeric G-proteins by G-protein coupled receptors (GPCRs). To this end, FRET based biosensors are made, employing heterotrimeric G-protein subunits
Externí odkaz:
https://doaj.org/article/fb7f53712c4d43f2ba1afea9d76b4818
Autor:
J Joris Witsenburg, Heike Glauner, Jörg P Müller, Johannes M M Groenewoud, Günter Roth, Frank-Dietmar Böhmer, Merel J W Adjobo-Hermans, Roland Brock
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e79277 (2013)
T cell signaling is triggered through stimulation of the T cell receptor and costimulatory receptors. Receptor activation leads to the formation of membrane-proximal protein microclusters. These clusters undergo tyrosine phosphorylation and organize
Externí odkaz:
https://doaj.org/article/416bec19ff2a409bba257c888199e820
Autor:
Joachim Goedhart, Laura van Weeren, Merel J W Adjobo-Hermans, Ies Elzenaar, Mark A Hink, Theodorus W J Gadella
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27321 (2011)
BACKGROUND: Co-expression of proteins is generally achieved by introducing two (or more) independent plasmids into cells, each driving the expression of a different protein of interest. However, the relative expression levels may vary strongly betwee
Externí odkaz:
https://doaj.org/article/b4af9cd9a1fb4c00a7d31d143907ddba
Autor:
Joachim Goedhart, Joop E M Vermeer, Merel J W Adjobo-Hermans, Laura van Weeren, Theodorus W J Gadella
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1011 (2007)
BACKGROUND: Fluorescence Resonance Energy Transfer (FRET) between the green fluorescent protein (GFP) variants CFP and YFP is widely used for the detection of protein-protein interactions. Nowadays, several monomeric red-shifted fluorescent proteins
Externí odkaz:
https://doaj.org/article/2ea7e26f91614f0f8caa0c0f0a3b2314
Autor:
Elianne P Bulthuis, Cindy E J Dieteren, Jesper Bergmans, Job Berkhout, Jori A Wagenaars, Els M A van de Westerlo, Emina Podhumljak, Mark A Hink, Laura F B Hesp, Hannah S Rosa, Afshan N Malik, Mariska Kea‐te Lindert, Peter H G M Willems, Han J G E Gardeniers, Wouter K den Otter, Merel J W Adjobo‐Hermans, Werner J H Koopman
Publikováno v:
EMBO Journal, 42
EMBO Journal 42 (2023) 7
EMBO Journal, 42, 7
EMBO Journal, 42(7)
EMBO Journal 42 (2023) 7
EMBO Journal, 42, 7
EMBO Journal, 42(7)
Contains fulltext : 291757.pdf (Publisher’s version ) (Open Access) Macromolecules of various sizes induce crowding of the cellular environment. This crowding impacts on biochemical reactions by increasing solvent viscosity, decreasing the water-ac
Autor:
Albert Quintana, Judith Homberg, Merel J. W. Adjobo-Hermans, Mariusz R. Wieckowski, Sander Grefte, Melissa van de Wal, Jaap Keijer, Werner J H Koopman, Evert M. van Schothorst, Clara D.M. van Karnebeek, Tom J.J. Schirris
Publikováno v:
Brain, 145, 1, pp. 45-63
Brain, 145, 45-63
Brain, 145(1), 45-63
Brain, 145(1), 45-63. Oxford University Press
Brain 145 (2022) 1
Brain, 145, 45-63
Brain, 145(1), 45-63
Brain, 145(1), 45-63. Oxford University Press
Brain 145 (2022) 1
Mitochondria are small cellular constituents that generate cellular energy (ATP) by oxidative phosphorylation (OXPHOS). Dysfunction of these organelles is linked to a heterogeneous group of multisystemic disorders, including diabetes, cancer, ageing-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29f553cee4ad34628f044c06a43ee8b
Publikováno v:
Antioxid Redox Signal
Antioxidants & Redox Signaling, 30, 2066-2109
Antioxidants & Redox Signaling, 30, 18, pp. 2066-2109
Antioxidants & Redox Signaling, 30, 2066-2109
Antioxidants & Redox Signaling, 30, 18, pp. 2066-2109
Contains fulltext : 204156.pdf (Publisher’s version ) (Open Access) Significance: In addition to their classical role in cellular ATP production, mitochondria are of key relevance in various (patho)physiological mechanisms including second messenge
Autor:
Changbo Qu, Merel J. W. Adjobo-Hermans, Melissa A.E. van de Wal, Werner J.H. Koopman, Yihang Pan, Clara D.M. van Karnebeek, Tom J.J. Schirris, Jaap Keijer
Publikováno v:
International Journal of Biochemistry & Cell Biology, 138
International Journal of Biochemistry and Cell Biology 138 (2021)
international journal of biochemistry & cell biology, 138:106050. Elsevier Limited
International Journal of Biochemistry and Cell Biology, 138
International Journal of Biochemistry and Cell Biology 138 (2021)
international journal of biochemistry & cell biology, 138:106050. Elsevier Limited
International Journal of Biochemistry and Cell Biology, 138
Classical mitochondrial disease (MD) represents a group of complex metabolic syndromes primarily linked to dysfunction of the mitochondrial ATP-generating oxidative phosphorylation (OXPHOS) system. To date, effective therapies for these diseases are
Publikováno v:
Methods in cell biology. 155
Assessment of the mitochondrial membrane potential (Δψ) in living cells, although not trivial, can be used to estimate mitochondrial bioenergetic state. For this purpose, fluorescent lipophilic cations are broadly applied. These cations enter cells