Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Merel E. P. Wilmsen"'
Autor:
Manzhi Zhao, Ling Li, Caoimhe H. Kiernan, Melisa D. Castro Eiro, Floris Dammeijer, Marjan van Meurs, Inge Brouwers-Haspels, Merel E. P. Wilmsen, Dwin G. B. Grashof, Harmen J. G. van de Werken, Rudi W. Hendriks, Joachim G. Aerts, Yvonne M. Mueller, Peter D. Katsikis
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Cytotoxic CD8 + T cell (CTL) exhaustion is driven by chronic antigen stimulation. Reversing CTL exhaustion with immune checkpoint blockade (ICB) has provided clinical benefits in different types of cancer. We, therefore, investigated whether
Externí odkaz:
https://doaj.org/article/894d1a0cf952487080d6943e463aba2e
Autor:
Ling Li, Manzhi Zhao, Caoimhe H. Kiernan, Melisa D. Castro Eiro, Marjan van Meurs, Inge Brouwers-Haspels, Merel E. P. Wilmsen, Dwin G. B. Grashof, Harmen J. G. van de Werken, Rudi W. Hendriks, Yvonne M. Mueller, Peter D. Katsikis
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionCytotoxic CD8+ T cell (CTL) exhaustion is a dysfunctional state of T cells triggered by persistent antigen stimulation, with the characteristics of increased inhibitory receptors, impaired cytokine production and a distinct transcriptiona
Externí odkaz:
https://doaj.org/article/3847fcbb75c24886b8cbbde00a41f92f
Autor:
Yvonne M. Mueller, Thijs J. Schrama, Rik Ruijten, Marco W. J. Schreurs, Dwin G. B. Grashof, Harmen J. G. van de Werken, Giovanna Jona Lasinio, Daniel Álvarez-Sierra, Caoimhe H. Kiernan, Melisa D. Castro Eiro, Marjan van Meurs, Inge Brouwers-Haspels, Manzhi Zhao, Ling Li, Harm de Wit, Christos A. Ouzounis, Merel E. P. Wilmsen, Tessa M. Alofs, Danique A. Laport, Tamara van Wees, Geoffrey Kraker, Maria C. Jaimes, Sebastiaan Van Bockstael, Manuel Hernández-González, Casper Rokx, Bart J. A. Rijnders, Ricardo Pujol-Borrell, Peter D. Katsikis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Developing predictive methods to identify patients with high risk of severe COVID-19 disease is of crucial importance. Authors show here that by measuring anti-SARS-CoV-2 antibody and cytokine levels at the time of hospital admission and integrating
Externí odkaz:
https://doaj.org/article/8868b5c6ee1046f79b63a7f738da79df
Autor:
Thijs J Schrama, Danique A. Laport, Caoimhe H. Kiernan, Manzhi Zhao, Bart J. A. Rijnders, Casper Rokx, Sebastiaan Van Bockstael, Maria C. Jaimes, Ling Li, Dwin G.B. Grashof, Christos A. Ouzounis, Merel E. P. Wilmsen, Daniel Alvarez de la Sierra, Harmen J.G. van de Werken, Tamara van Wees, Inge Brouwers-Haspels, Manuel Hernández-González, Melisa D. Castro Eiro, Marco W.J. Schreurs, Marjan van Meurs, Geoffrey Kraker, Yvonne M. Mueller, Ricardo Pujol-Borrell, Peter D. Katsikis, Harm de Wit, Rik Ruijten, Tessa Alofs
Quantitative or qualitative differences in immunity may drive and predict clinical severity in COVID-19. We therefore measured modules of serum pro-inflammatory, anti-inflammatory and anti-viral cytokines in combination with the anti-SARS-CoV-2 antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ee7016575b8d7f20a18e3f8667441e0
https://doi.org/10.1101/2021.05.07.21256531
https://doi.org/10.1101/2021.05.07.21256531
