Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mereena George Ushakumary"'
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 7, Pp 1021-1032 (2021)
Abstract Developing, regenerating, and repairing a lung all require interstitial resident fibroblasts (iReFs) to direct the behavior of the epithelial stem cell niche. During lung development, distal lung fibroblasts, in the form of matrix‐, myo‐
Externí odkaz:
https://doaj.org/article/7110469d517645c5b39f5f3eb763f297
Autor:
Matthew R. Riccetti, Mereena George Ushakumary, Marion Waltamath, Jenna Green, John Snowball, Sydney E. Dautel, Mehari Endale, Bonny Lami, Jason Woods, Shawn K. Ahlfeld, Anne-Karina T. Perl
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Infants born prematurely worldwide have up to a 50% chance of developing bronchopulmonary dysplasia (BPD), a clinical morbidity characterized by dysregulated lung alveolarization and microvascular development. It is known that PDGFR alpha–positive
Externí odkaz:
https://doaj.org/article/b64d940fd4a04216a9cec3d2b72e8c02
Autor:
Mereena George Ushakumary, Mingyi Wang, Harikrishnan V, Allen Sam Titus, Jing Zhang, Lijuan Liu, Robert Monticone, Yushi Wang, Julie A Mattison, Rafael de Cabo, Edward G Lakatta, Shivakumar Kailasam
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225911 (2019)
Collagen accumulation and remodeling in the vascular wall is a cardinal feature of vascular fibrosis that exacerbates the complications of hypertension, aging, diabetes and atherosclerosis. With no specific therapy available to date, identification o
Externí odkaz:
https://doaj.org/article/01c27aa1a8eb4f21b1fb4431cd1bfc70
Autor:
Allen Sam Titus, Mereena George Ushakumary, Harikrishnan Venugopal, Mingyi Wang, Edward G. Lakatta, Shivakumar Kailasam
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 585
Molecular mechanisms underlying the diverse therapeutic effects of anti-diabetic metformin, beyond its anti-hyperglycaemic effects, remain largely unclear. Metformin is reported to reduce the long-term complications of diabetes, including cardiovascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d59edb4a7e3f3848b24d05b20dac2f
https://pubmed.ncbi.nlm.nih.gov/36614028
https://pubmed.ncbi.nlm.nih.gov/36614028
Autor:
Allen Sam Titus, Mereena George Ushakumary, Harikrishnan Venugopal, Mingyi Wang, Edward G. Lakatta, Shivakumar Kailasam
Molecular mechanisms underlying the diverse therapeutic effects of anti-diabetic metformin, beyond its anti-hyperglycaemic effects, remain largely unclear. Metformin is reported to reduce the long-term complications of diabetes, including cardiovascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e6b19e66615a899f9e8312369ff4dc1
https://doi.org/10.1101/2022.10.24.513528
https://doi.org/10.1101/2022.10.24.513528
Autor:
Mereena George Ushakumary, Jenna Green, Matthew Richard Riccetti, Cheng-Lun Na, Divya Mohanraj, Minzhe Guo, Anne-Karina Theresia Perl
Alveolarization is dependent on myo-, matrix- and lipo- fibroblast functions by interstitial PDGFRa+ fibroblasts. While these fibroblasts are derived from GLI and PDGFRa expressing fibroblasts, the transcriptional control of their functional specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ec9dbb6fafa159c337cf306d830d674
https://doi.org/10.1101/2022.06.06.494950
https://doi.org/10.1101/2022.06.06.494950
Autor:
Devendra K. Agrawal, S.R. Aravind, Sunitha Chandran, Soumya Chandrasekher, Smitha Chenicheri, Bodhisatwa Das, Francis Boniface Fernandez, Annie John, Jessy John, Josna Joseph, Remya Kommeri, P. Lekshmi, Bernadette K. Madathil, Krupa Ann Mathew, S. Mini, Daniel Miranda, Sujata Mohanty, Anwesha Mukherjee, Renjith P. Nair, E. Pranshu Rao, David Jesse Sanchez, Chandra P. Sharma, Yashvi Sharma, Finosh G. Thankam, Ancy Thomas, Jane Joy Thomas, Mereena George Ushakumary, Daniel R. Wilson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b117683189c7d1a4b587463afc626a
https://doi.org/10.1016/b978-0-323-89972-7.09991-8
https://doi.org/10.1016/b978-0-323-89972-7.09991-8
Autor:
Allen Sam Titus, Mereena George Ushakumary, Shivakumar Kailasam, Harikrishnan Venugopal, Mingyi Wang, Randy T. Cowling, Edward G. Lakatta
Publikováno v:
International journal of molecular sciences, vol 22, iss 17
International Journal of Molecular Sciences
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9343, p 9343 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9343, p 9343 (2021)
Recent reports on the cardioprotective effects of fibronectin inhibition following myocardial injury suggest a largely unexplored role for the extracellular matrix (ECM) glycoprotein in cardiac fibroblast function. We probed the molecular regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45ee3d341a7ef2781b2ee6691001e66
https://escholarship.org/uc/item/7j97q35m
https://escholarship.org/uc/item/7j97q35m