Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Meredyth G. Ll. Wilkinson"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder in which pathogenic abnormalities within both the innate and adaptive immune response have been described. In order to activated, proliferate and maintain this immunological response
Externí odkaz:
https://doaj.org/article/1265acae845d4c508f2f70bf4f850bdc
Autor:
Christopher J. M. Piper, Meredyth G. Ll. Wilkinson, Claire T. Deakin, Georg W. Otto, Stefanie Dowle, Chantal L. Duurland, Stuart Adams, Emiliano Marasco, Elizabeth C. Rosser, Anna Radziszewska, Rita Carsetti, Yiannis Ioannou, Philip L. Beales, Daniel Kelberman, David A. Isenberg, Claudia Mauri, Kiran Nistala, Lucy R. Wedderburn
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Juvenile dermatomyositis (JDM) is a rare form of childhood autoimmune myositis that presents with proximal muscle weakness and skin rash. B cells are strongly implicated in the pathogenesis of the disease, but the underlying mechanisms are unknown. T
Externí odkaz:
https://doaj.org/article/d4e3bfbc2edb40d1b0de07db8cb6975c
Autor:
Charalampia Papadopoulou, Christine Chew, Meredyth G. Ll. Wilkinson, Liza McCann, Lucy R. Wedderburn
Publikováno v:
Nature Reviews Rheumatology. 19:343-362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a4e52594b9c11a5f96586b80f8304e4
https://doi.org/10.1038/s41584-023-00967-9
https://doi.org/10.1038/s41584-023-00967-9
Autor:
Meredyth G Ll Wilkinson, Dale Moulding, Thomas C R McDonnell, Michael Orford, Chris Wincup, Joanna Y J Ting, Georg W Otto, Restuadi Restuadi, Daniel Kelberman, Charalampia Papadopoulou, Sergi Castellano, Simon Eaton, Claire T Deakin, Elizabeth C Rosser, Lucy R Wedderburn
Publikováno v:
Annals of the Rheumatic Diseases. 82:658-669
ObjectivesTo define the host mechanisms contributing to the pathological interferon (IFN) type 1 signature in Juvenile dermatomyositis (JDM).MethodsRNA-sequencing was performed on CD4+, CD8+, CD14+and CD19+cells sorted from pretreatment and on-treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9741e1d25871979cea9c0c8d8dec5195
https://doi.org/10.1136/ard-2022-223469
https://doi.org/10.1136/ard-2022-223469
Autor:
Meredyth G. Ll Wilkinson, Lucy R. Wedderburn, Claire T Deakin, Charalampia Papadopoulou, Despina Eleftheriou
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-12 (2021)
Pediatric Rheumatology Online Journal
Pediatric Rheumatology Online Journal
Juvenile Idiopathic Inflammatory Myopathies (IIM) are a group of rare diseases that are heterogeneous in terms of pathology that can include proximal muscle weakness, associated skin changes and systemic involvement. Despite options for treatment, ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba02b4e281889a994703f3181408d8a
https://doaj.org/article/c6db7ec23f564c74aa0fb814dd86dde8
https://doaj.org/article/c6db7ec23f564c74aa0fb814dd86dde8
Autor:
Dhira Joshi, Lucy R. Marshall, Lucy R. Wedderburn, Stavroula Paraskevopoulou, Steve Gamblin, Georgina H. Cornish, Sonia Gandhi, Charles Swanton, John W. McCauley, William Bolland, Svend Kjaer, Nikhil Faulkner, Hannah Rickman, Rachel Ulferts, Philip Hobson, D.J. Benton, Laura E. McCoy, Ana Agua-Doce, Rupert Beale, Annachiara Rosa, Chloe Roustan, Nicola O’Reilly, Catherine F Houlihan, Christopher Earl, Eleni Nastouli, A.G. Wrobel, Rachael Thompson, Brigitta Stockinger, Kirsty Thomson, Catherine Moore, Bethany R. Jebson, Anna Radziszewska, Coziana Ciurtin, Andrew Riddell, Saira Hussain, Emilie Sanchez, Peter Cherepanov, Elizabeth C. Rosser, Meredyth G. Ll Wilkinson, Kevin W. Ng, Ruth Harvey, Philip A. Walker, Hannah Peckham, Judith Heaney, Gee Yen Shin, Moira J. Spyer, George Kassiotis
Publikováno v:
Science (New York, N.y.)
Science
Science
Antibodies predating infection Immunological memory after infection with seasonal human coronaviruses (hCoVs) may potentially contribute to cross-protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Ng et al. report that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b78b2fb2e3b3317126ad45bbfb9684
https://doi.org/10.1126/science.abe1107
https://doi.org/10.1126/science.abe1107
Autor:
Coziana Ciurtin, Judith Heaney, John W. McCauley, Hannah Peckham, Peter Cherepanov, Anna Radziszewska, Lucy R. Marshall, Lucy R. Wedderburn, Ruth Harvey, Moira J. Spyer, Stavroula Paraskevopoulou, Annachiara Rosa, Kevin W. Ng, Eleni Nastouli, Saira Hussain, George Kassiotis, Elizabeth C. Rosser, Catherine F Houlihan, Nikhil Faulkner, Joshua Hope, William Bolland, Bethany R. Jebson, Hannah Rickman, Steve Gamblin, Georgina H. Cornish, Christopher Earl, Harsita Patel, Michael Levin, Kathryn O’Brien, Claire T. Deakin, Meredyth G. Ll Wilkinson
Publikováno v:
Med (New York, N.y.)
Background Differences in humoral immunity to coronaviruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), between children and adults remain unexplained and the impact of underlying immune dysfunction or suppression unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee35fa144fb7dc62d2e7f5997f0a3e2e
https://doi.org/10.1016/j.medj.2021.08.001
https://doi.org/10.1016/j.medj.2021.08.001
Autor:
David A. Isenberg, Jessica J Manson, Meredyth G. Ll Wilkinson, Yiannis Ioannou, Chris Wincup, Anna Radziszewska, Elizabeth C. Jury
Publikováno v:
Rheumatology (Oxford, England). 59(1)
ObjectiveThe inflammatory idiopathic myopathies (IIM) are a group of rare autoimmune diseases defined by muscle weakness and characterized by pro-inflammatory infiltrates in muscle. Little is known about the immunological profile in peripheral blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2c978a21451ad91e42fb5a47223bce
https://pubmed.ncbi.nlm.nih.gov/31292651
https://pubmed.ncbi.nlm.nih.gov/31292651
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
B cells carry out a central role in the pathogenesis of autoimmune disease. In addition to the production of autoantibodies, B cells can contribute to disease development by presenting autoantigens to autoreactive T cells and by secreting pro-inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::234ae5047cde556d0a85fe07abaa1563
https://www.frontiersin.org/article/10.3389/fimmu.2019.00214/full
https://www.frontiersin.org/article/10.3389/fimmu.2019.00214/full
Publikováno v:
Frontiers in Immunology
B cells carry out a central role in the pathogenesis of autoimmune disease. In addition to the production of autoantibodies, B cells can contribute to disease development by presenting autoantigens to autoreactive T cells and by secreting pro-inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c068f80ac81cc9d7a1bef90b067733d
https://pubmed.ncbi.nlm.nih.gov/30837988
https://pubmed.ncbi.nlm.nih.gov/30837988