Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Meredith Hay"'
Autor:
Maha I. Sulaiman, Wafaa Alabsi, Lajos Szabo, Meredith Hay, Robin Polt, Tally M. Largent-Milnes, Todd W. Vanderah
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 15007 (2023)
Pain is the most significant impairment and debilitating challenge for patients with bone metastasis. Therefore, the primary objective of current therapy is to mitigate and prevent the persistence of pain. Thus, cancer-induced bone pain is described
Externí odkaz:
https://doaj.org/article/c4d8185fc5ce499e9097d6c375a5250a
Autor:
Christina Hoyer-Kimura, John P. Konhilas, Heidi M. Mansour, Robin Polt, Kristian P. Doyle, Dean Billheimer, Meredith Hay
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background Decreased cerebral blood flow and systemic inflammation during heart failure (HF) increase the risk for vascular contributions to cognitive impairment and dementia (VCID) and Alzheimer disease-related dementias (ADRD). We previous
Externí odkaz:
https://doaj.org/article/1f581aace31e48588560b1ea25934274
Autor:
Ryan P. Bruhns, Maha Ibrahim Sulaiman, Michael Gaub, Esther H. Bae, Rachel B. Davidson Knapp, Anna R. Larson, Angela Smith, Deziree L. Coleman, William D. Staatz, Alexander J. Sandweiss, Bellal Joseph, Meredith Hay, Tally M. Largent-Milnes, Todd W. Vanderah
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
IntroductionTraumatic brain injury (TBI) is a leading cause of disability in the US. Angiotensin 1-7 (Ang-1-7), an endogenous peptide, acts at the G protein coupled MAS1 receptors (MASR) to inhibit inflammatory mediators and decrease reactive oxygen
Externí odkaz:
https://doaj.org/article/8d2363e03db44e41afd84e454813225b
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 587 (2022)
Heart failure (HF) causes decreased brain perfusion in older adults, and increased brain and systemic inflammation increases the risk of cognitive impairment and Alzheimer’s disease (AD). Glycosylated Ang-(1-7) MasR agonists (PNA5) has shown improv
Externí odkaz:
https://doaj.org/article/c1ba98e2d7d141afb2d236efee83736a
Autor:
Katie L. Collins, Usir S. Younis, Sasipa Tanyaratsrisakul, Robin Polt, Meredith Hay, Heidi M. Mansour, Julie G. Ledford
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1614 (2021)
The peptide hormone, angiotensin (Ang-(1–7)), produces anti-inflammatory and protective effects by inhibiting production and expression of many cytokines and adhesion molecules that are associated with a cytokine storm. While Ang-(1–7) has been s
Externí odkaz:
https://doaj.org/article/1c3f178421064d01a2f3cbcffc325495
Autor:
Wafaa Alabsi, Maria F. Acosta, Fahad A. Al-Obeidi, Meredith Hay, Robin Polt, Heidi M. Mansour
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1278 (2021)
The peptide hormone Angiotensin (1—7), Ang (1—7) or (Asp-Arg-Val-Tyr-Ile-His-Pro), is an essential component of the renin–angiotensin system (RAS) peripherally and is an agonist of the Mas receptor centrally. Activation of this receptor in the
Externí odkaz:
https://doaj.org/article/1b5d4420ffd749ccba3b74445c0c6dba
Autor:
Lee Ryan, Meredith Hay, Matt J. Huentelman, Audrey Duarte, Tatjana Rundek, Bonnie Levin, Anja Soldan, Corinne Pettigrew, Matthias R. Mehl, Carol A. Barnes
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
The current “one size fits all” approach to our cognitive aging population is not adequate to close the gap between cognitive health span and lifespan. In this review article, we present a novel model for understanding, preventing, and treating a
Externí odkaz:
https://doaj.org/article/1aef8d8a13de42989fd5426f19428d92
Autor:
Joshua S Talboom, Asta Håberg, Matthew D De Both, Marcus A Naymik, Isabelle Schrauwen, Candace R Lewis, Stacy F Bertinelli, Callie Hammersland, Mason A Fritz, Amanda J Myers, Meredith Hay, Carol A Barnes, Elizabeth Glisky, Lee Ryan, Matthew J Huentelman
Publikováno v:
eLife, Vol 8 (2019)
In humans, a first-degree family history of dementia (FH) is a well-documented risk factor for Alzheimer’s disease (AD); however, the influence of FH on cognition across the lifespan is poorly understood. To address this issue, we developed an inte
Externí odkaz:
https://doaj.org/article/3219f8c4a75445a8b170514e5d38165e
Autor:
Christina Hoyer-Kimura, John Konhilas, Paulo Pires, Christopher Banek, Melissa Dennis, Victoria Salcedo, Meredith Hay
Publikováno v:
Physiology. 38
Dynamic cerebral blood flow (CBF) regulation via neurovascular coupling (NVC) is essential to meet localized brain oxygen and nutrient demands. Cerebral microvascular dysfunction contributes to the pathogenesis of many types of dementias. Previous st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c1bf5490457466de956027fe9755c2
https://doi.org/10.1152/physiol.2023.38.s1.5735136
https://doi.org/10.1152/physiol.2023.38.s1.5735136
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1f41283e824e24c3d2b722197aaea38
https://doi.org/10.1002/alz.059909
https://doi.org/10.1002/alz.059909