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pro vyhledávání: '"Meredith Dever"'
Autor:
Neetha Parameswaran, Meredith Dever, Joel Chen, Mitchell R. Smith, Shelley Beth Robinson, Deepa Jagadeesh, Robert M. Dean, Yogen Saunthararajah, Ashley Morrison, Brian T. Hill, Sherry Fada, Brad Pohlman, Daniel J. Lindner, Tomas Radivoyevitch
Publikováno v:
Semin Hematol
One mechanism by which lymphoid malignancies resist standard apoptosis-intending (cytotoxic) treatments is genetic attenuation of the p53/p16-CDKN2A apoptosis axis. Depletion of the epigenetic protein DNA methyltransferase 1 (DNMT1) using the deoxycy