Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Meredith Crosby"'
Autor:
Elena Favaro, Anassuya Ramachandran, Robert McCormick, Harriet Gee, Christine Blancher, Meredith Crosby, Cecilia Devlin, Christopher Blick, Francesca Buffa, Ji-Liang Li, Borivoj Vojnovic, Ricardo Pires das Neves, Peter Glazer, Francisco Iborra, Mircea Ivan, Jiannis Ragoussis, Adrian L Harris
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10345 (2010)
Hypoxia in cancers results in the upregulation of hypoxia inducible factor 1 (HIF-1) and a microRNA, hsa-miR-210 (miR-210) which is associated with a poor prognosis.In human cancer cell lines and tumours, we found that miR-210 targets the mitochondri
Externí odkaz:
https://doaj.org/article/4b262f404a274363b024a45e2a841996
Publikováno v:
Environmental and Molecular Mutagenesis. 62:4-17
Hydrazine has been described as a mutagenic, probable human carcinogen. It is mutagenic in in vitro systems such as bacterial reverse mutation (Ames) tests and some yeast systems, as well as in in vivo systems with drosophila. It was shown to cause c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a94467341eac707fef7b1012b723a11
https://doi.org/10.1002/em.22406
https://doi.org/10.1002/em.22406
Autor:
Junguo Zhou, Paul Butler, Meredith Crosby, Laura Aschenbrenner, Jim Blank, Jonathan G. Moggs, Vincent L. Reynolds, Kyle L. Kolaja, Derek D. Best, Dana Shuey, Matthew M. Abernathy, Terry R. Van Vleet, Chelsea Snyder, Patricia A. Escobar, Timothy K. Hart, Laura Custer
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 117
Pharmaceutic products designed to perturb the function of epigenetic modulators have been approved by regulatory authorities for treatment of advanced cancer. While the predominant effort in epigenetic drug development continues to be in oncology, no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0c03ba3f1ed7746ed6a53efdd5ecdd
https://pubmed.ncbi.nlm.nih.gov/32911461
https://pubmed.ncbi.nlm.nih.gov/32911461
Autor:
John Nicolette, Alison Kondratiuk, G. Jayakumar, Paul Sonders, Meredith Crosby, A. Patel, Emily Dakoulas, Joel Murray, Kamala Pant, R. Vicente, K. Datta, M. Mathur, Rohan Kulkarni, Kyle L. Kolaja
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 100
The bacterial reverse mutation assay (Ames) is a fundamental genetic toxicology test, and efforts to miniaturize the regulatory GLP version are essential in assessing genotoxic liabilities earlier in the drug development pipeline. Two versions of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623336ead26e589cf83fdf5be3a0b00a
https://pubmed.ncbi.nlm.nih.gov/30401633
https://pubmed.ncbi.nlm.nih.gov/30401633
Publikováno v:
Mutagenesis. 32(1)
In a previous study, 15-nm silica nanoparticles (NPs) caused small increases in DNA damage in liver as measured in the in vivo comet and micronucleus assays after intravenous administration to rats at their maximum tolerated dose, a worst-case exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c43c28cac6c09fb220a1e65afd54cf8
https://pubmed.ncbi.nlm.nih.gov/27864332
https://pubmed.ncbi.nlm.nih.gov/27864332
Autor:
Meredith Crosby
Publikováno v:
Cancer & Metastasis Reviews; Jun2007, Vol. 26 Issue 2, p249-260, 12p
Publikováno v:
Neurochemical Research; Apr2007, Vol. 32 Issue 4/5, p639-644, 6p