Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Meredith Chittenden"'
Autor:
Megan Sykes, Meredith Chittenden, Akira Shimizu, Yasuhiro Fudaba, Takashi Onoe, Roderick T. Bronson, Juanita Shaffer
Publikováno v:
The Journal of Immunology. 181:7649-7659
Porcine thymus grafts support robust murine and human thymopoiesis, generating a diverse T cell repertoire that is deleted of donor and host-reactive cells, achieving specific xenograft tolerance. Positive selection is mediated exclusively by the xen
Autor:
Fabienne Haspot, Thomas Fehr, Meredith Chittenden, Joshua Mollov, Timothy P. Hogan, Megan Sykes
Publikováno v:
The Journal of Immunology. 181:165-173
Allogeneic bone marrow chimerism induces robust systemic tolerance to donor alloantigens. Achievement of chimerism requires avoidance of marrow rejection by pre-existing CD4 and CD8 T cells, either of which can reject fully MHC-mismatched marrow. Bot
Publikováno v:
Clinical Immunology. 120:33-44
In mixed chimeras prepared with nonmyeloablative conditioning, we previously showed that recipient leukocyte infusions (RLI) induced loss of donor chimerism and anti-tumor responses against the A20 BALB/c B cell lymphoma. We also previously showed th
Autor:
Megan Sykes, Hannes Kalscheuer, Yong-Guang Yang, Meredith Chittenden, Takashi Onoe, Nichole M. Danzl, Guiling Zhao
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(7)
CD4+ regulatory T cells (Tregs) control adaptive immune responses and promote self-tolerance. Various humanized mouse models have been developed in efforts to reproduce and study a human immune system. However, in models that require T cell different
Autor:
Megan Sykes, Giovanna Andreola, N. T. Tolkoff-Rubin, T. Bonnefoix, Juanita Shaffer, Tatsuaki Morokata, Meredith Chittenden, Frederic I. Preffer, David H. Sachs, Thomas R. Spitzer, Bimalangshu R. Dey, Samuel A. LoCascio, Kristin Kattleman, Pete Cotter, Cosimi Ab, Tatsuo Kawai
We recently reported long-term organ allograft survival without ongoing immunosuppression in four of five patients receiving combined kidney and bone marrow transplantation from haploidentical donors following nonmyeloablative conditioning. In vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84175647e4cc11c446ed937558745a84
https://europepmc.org/articles/PMC3140222/
https://europepmc.org/articles/PMC3140222/
Autor:
Meredith Chittenden, Frederic I. Preffer, Samuel A. LoCascio, David Dombkowski, Tatsuaki Morokata, Giovanna Andreola, Tatsuo Kawai, Megan Sykes, David H. Sachs, A. Benedict Cosimi, Susan L. Saidman, Nina Tolkoff-Rubin, Thomas R. Spitzer, Kerry Crisalli
Publikováno v:
Transplantation. 90(12)
Background. We have previously reported operational tolerance in patients receiving human leukocyte antigen-mismatched combined kidney and bone marrow transplantation (CKBMT). We now report on transient multilineage hematopoietic chimerism and lympho
Autor:
Guiling Zhao, Megan Sykes, Hannes Kalscheuer, Yong-Guang Yang, Meredith Chittenden, Takashi Onoe
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(12)
Immune recovery in lymphopenic hosts depends largely on homeostatic peripheral expansion, especially when thymopoiesis is insufficient, as is often the case in human adults. Although it has been well studied in mice, the study of homeostatic peripher
Autor:
Thomas R. Spitzer, Meredith Chittenden, David H. Sachs, J. De Vito, Fabrice Porcheray, Megan Sykes, Bimalangshu R. Dey, Cosimi Ab, Tatsuo Kawai, Emmanuel Zorn, Robert B. Colvin, Juanita Shaffer, Nina Tolkoff-Rubin, Susan L. Saidman, Waichi Wong, Timothy C. Girouard
Five patients with end-stage kidney disease received combined kidney and bone marrow transplants from HLA haploidentical donors following nonmyeloablative conditioning to induce renal allograft tolerance. Immunosuppressive therapy was successfully di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b92b7a276ce9746cde296dee8ae748
https://europepmc.org/articles/PMC2837587/
https://europepmc.org/articles/PMC2837587/
Autor:
Terry K. Means, Juanita Shaffer, Megan Sykes, Yasuhiro Fudaba, Ronjon Chakraverty, Andrew D. Luster, Meredith Chittenden, Marie T Rubio
Publikováno v:
International immunology. 17(12)
Prostaglandin E2 (PGE2) acts in synergy with other inflammatory stimuli such as tumor necrosis factor (TNF) to induce the maturation of migratory-type monocyte-derived dendritic cells (MoDCs). However, PGE2 has been reported to inhibit IL-12p70 produ
Autor:
Bimalangshu R. Dey, Giovanna Andreola, Nina Tolkoff-Rubin, David H. Sachs, Meredith Chittenden, Susan L. Saidman, Frederic I. Preffer, Benedict Cosimi, Kristin Kattleman, Thomas R. Spitzer, Pete Cotter, Juanita Shaffer, Megan Sykes, Tatsuo Kawai
Publikováno v:
Clinical Immunology. 131:S60