Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Meredith A. Howell"'
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e100868 (2014)
Unattended hepatic insulin resistance predisposes individuals to dyslipidemia, type 2 diabetes and many other metabolic complications. The mechanism of hepatic insulin resistance at the gene expression level remains unrevealed. To examine the effects
Externí odkaz:
https://doaj.org/article/127a8964be1646398f20528f92e0205d
Background: Pegylated interferon-2a (PegIFN-2a)+ribavirin treatment for chronic hepatitis C is often associated with depressive symptoms. Previous studies have failed to explore whether PegIFN-2a pharmacokinetic variability plays an etiologic role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a82ca5470282c9f08d887381d8bb145
Publikováno v:
Biochemistry. 35:15373-15382
Spermine has been shown to bind to and stabilize a number of altered DNA conformations, including left-handed Z-DNA. Here, we have quantitatively studied the effects of spermine on the negative supercoil-induced transition from B- to Z-DNA. We have d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e14a7c1a919c78565edfaa7a097ceea
https://doi.org/10.1021/bi961881i
https://doi.org/10.1021/bi961881i
Autor:
Tuesday Hancock, Dennis A. Carson, Ian P. Wicks, Hitoshi Kohsaka, Tsaiwei Olee, Meredith L. Howell
Publikováno v:
Human gene therapy. 6(3)
During the course of gene therapy experiments in rodents, using intramuscular injections of plasmid DNA derived from Escherichia coli, we noted dose-related toxicity. This observation prompted a search for possible contaminants of DNA samples. We use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3783534f5172049215e621f468c1ba
https://pubmed.ncbi.nlm.nih.gov/7779915
https://pubmed.ncbi.nlm.nih.gov/7779915
Publikováno v:
Nucleic acids research. 21(25)
We present a study of how substituent groups of naturally occurring and modified nucleotide bases affect the degree of hydration of right-handed B-DNA and left-handed Z-DNA. A comparison of poly(dG-dC) and poly(dG-dm5C) titrations with the lipotropic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950f1fd5988bf7f3e848ed8267038df0
https://pubmed.ncbi.nlm.nih.gov/8290360
https://pubmed.ncbi.nlm.nih.gov/8290360
Publikováno v:
Journal of molecular recognition : JMR. 1(1)
We have isolated a highly enriched preparation of the multienzyme complex which synthesizes deoxyribonucleoside triphosphates (dNTPs) from bacteriophage T4-infected bacteria. By a combination of SDS polyacrylamide gel electrophoresis and assays for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a105e393447151cd160d1a5949bac2
https://pubmed.ncbi.nlm.nih.gov/3078839
https://pubmed.ncbi.nlm.nih.gov/3078839
Publikováno v:
Professional Medical Journal. 2016, Vol. 23 Issue 6, p750-755. 6p.
Publikováno v:
PLoS ONE. Aug2014, Vol. 9 Issue 8, p1-13. 13p.
Publikováno v:
Journal of Molecular Recognition; Feb1988, Vol. 1 Issue 1, p48-57, 10p
Publikováno v:
Journal of Cellular Biochemistry; Mar1993 Supplement 17D, Vol. 53, p139-168, 30p