Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Meredith A. Benson"'
Autor:
Alexa Price-Whelan, Chun Kit Poon, Meredith A. Benson, Tess T. Eidem, Christelle M. Roux, Jeffrey M. Boyd, Paul M. Dunman, Victor J. Torres, Terry A. Krulwich
Publikováno v:
mBio, Vol 4, Iss 4 (2013)
ABSTRACT Staphylococcus aureus exhibits an unusually high level of osmotolerance and Na+ tolerance, properties that support survival in various host niches and in preserved foods. The genetic basis of these traits is not well understood. We compared
Externí odkaz:
https://doaj.org/article/9b4328fbcb9c4b819ce98ffec2f6dcef
Publikováno v:
PLoS Pathogens, Vol 6, Iss 3, p e1000802 (2010)
The Staphylococcus aureus HrtAB system is a hemin-regulated ABC transporter composed of an ATPase (HrtA) and a permease (HrtB) that protect S. aureus against hemin toxicity. S. aureus strains lacking hrtA exhibit liver-specific hyper-virulence and up
Externí odkaz:
https://doaj.org/article/6fbc14d2cad44a9aa8fe7ef4bbaa381c
Autor:
Susan M. Robey-Bond, Susan S. Wallace, Ramiro Barrantes-Reynolds, Jeffrey P. Bond, Meredith A. Benson
Publikováno v:
DNA Repair. 53:43-51
The base excision repair DNA glycosylases, EcoNth and hNTHL1, are homologous, with reported overlapping yet different substrate specificities. The catalytic amino acid residues are known and are identical between the two enzymes although the exact st
Autor:
Victor J. Torres, Meredith A. Benson, Manisha Vaish, Francis Alonzo, Tamara Reyes-Robles, Alexa Price-Whelan, Terry A. Krulwich, Amyeo Jereen, Stephanie Christie, Jun Liu
Publikováno v:
Journal of Bacteriology
Staphylococcus aureus has three types of cation/proton antiporters. The type 3 family includes two m ultisubunit N a + / H + (Mnh) antiporters, Mnh1 and Mnh2. These antiporters are clusters of seven hydrophobic membrane-bound protein subunits. Mnh an
Autor:
Heidi A. Crosby, Victor J. Torres, Paul M. Dunman, Meredith A. Benson, Alexander R. Horswill, Joe M. Mootz, Tammy Kielian, Cortney E. Heim, Jeffrey S. Kavanaugh
Publikováno v:
Molecular Microbiology. 96:388-404
Summary Staphylococcus aureus is a significant cause of chronic biofilm infections on medical implants. We investigated the biofilm regulatory cascade and discovered that the repressor of toxins (Rot) is part of this pathway. A USA300 community-assoc
Autor:
Zuelay Rosario-Cruz, William M. Nauseef, Laura A. Mike, Harsimranjit K. Chahal, Ameya A. Mashruwala, Victor J. Torres, Jeffrey M. Boyd, Meredith A. Benson, Eric P. Skaar, Yun Y. Pang
Publikováno v:
Molecular Microbiology. 95:383-409
The acquisition and metabolism of iron (Fe) by the human pathogen Staphylococcus aureus is critical for disease progression. S. aureus requires Fe to synthesize inorganic cofactors called iron-sulfur (Fe-S) clusters, which are required for functional
Autor:
Chanelle Ryan, Apurva Narechania, Anne-Catrin Uhlemann, Bo Shopsin, Victor J. Torres, Paul J. Planet, Gintaras Deikus, Sergios-Orestis Kolokotronis, Meredith A. Benson, Hannah Smith, Elizabeth A. Ohneck, Francis Alonzo, Robert Sebra, Sarah W. Satola
Publikováno v:
Molecular Microbiology. 93:664-681
Staphylococcus aureus has evolved as a pathogen that causes a range of diseases in humans. There are two dominant modes of evolution thought to explain most of the virulence differences between strains. First, virulence genes may be acquired from oth
Publikováno v:
European Journal of Organic Chemistry. 2013:3560-3566
There is a significant unmet need for new antimicrobial agents that can address antimicrobial resistance. One promising group of antimicrobials is the antimicrobial peptides (AMPs) and their synthetic mimics. In particular, synthetic sequence-specifi
Publikováno v:
Regulation of Bacterial Virulence
Staphylococcus aureus is a gram-positive bacterium that is a component of the commensal flora of the skin and the nares. S. aureus is responsible for causing significant morbidity and mortality, resulting in nearly 300,000 hospitalizations and 19,000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6564f622293139b59c765e9c98b23dd8
https://doi.org/10.1128/9781555818524.ch4
https://doi.org/10.1128/9781555818524.ch4
Autor:
Richard P. Novick, Victor J. Torres, John Chen, Bo Shopsin, Meredith A. Benson, Francis Alonzo
Publikováno v:
Molecular Microbiology. 83:423-435
Bloodstream infection with Staphylococcus aureus is common and can be fatal. However, virulence factors that contribute to lethality in S. aureus bloodstream infection are poorly defined. We discovered that LukED, a commonly overlooked leucotoxin, is