Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Meredith A, Steeves"'
Autor:
Christopher P. Corkum, Louisa L. Wiede, Cara L.-A. Ruble, Jiabin Qiu, Patricia M. Mulrooney-Cousins, Meredith A. Steeves, David E. Watson, Tomasz I. Michalak
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Woodchuck (Marmota monax) infected with woodchuck hepatitis virus (WHV) is the most pathogenically compatible naturally occurring model of human hepatitis B virus (HBV) infection, chronic hepatitis B, and HBV-induced hepatocellular carcinoma. This sy
Externí odkaz:
https://doaj.org/article/3540bc6b9c5b47518ad3a62312db74a3
Autor:
John L. Cleveland, Anders E. Berglund, John M. Koomen, Zhihua Chen, Alexandar Tzankov, Andrea Ballabio, Meredith A. Steeves, Min Liu, Frank C. Dorsey, Stephanie K. Schaub, Seongseok Yun, Weimin Li, Chunying Yang, Franz X. Schaub, Mario R. Fernandez
Supplementary Figure from Disrupting the MYC-TFEB Circuit Impairs Amino Acid Homeostasis and Provokes Metabolic Anergy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11460843442b0396c4b5e694004b1d76
https://doi.org/10.1158/0008-5472.22431508.v1
https://doi.org/10.1158/0008-5472.22431508.v1
Autor:
John L. Cleveland, Anders E. Berglund, John M. Koomen, Zhihua Chen, Alexandar Tzankov, Andrea Ballabio, Meredith A. Steeves, Min Liu, Frank C. Dorsey, Stephanie K. Schaub, Seongseok Yun, Weimin Li, Chunying Yang, Franz X. Schaub, Mario R. Fernandez
Supplementary Data from Disrupting the MYC-TFEB Circuit Impairs Amino Acid Homeostasis and Provokes Metabolic Anergy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0460b6f75fe6376794a72fd32ccbb485
https://doi.org/10.1158/0008-5472.22431529.v1
https://doi.org/10.1158/0008-5472.22431529.v1
Autor:
John L. Cleveland, Anders E. Berglund, John M. Koomen, Zhihua Chen, Alexandar Tzankov, Andrea Ballabio, Meredith A. Steeves, Min Liu, Frank C. Dorsey, Stephanie K. Schaub, Seongseok Yun, Weimin Li, Chunying Yang, Franz X. Schaub, Mario R. Fernandez
MYC family oncoproteins are regulators of metabolic reprogramming that sustains cancer cell anabolism. Normal cells adapt to nutrient-limiting conditions by activating autophagy, which is required for amino acid (AA) homeostasis. Here we report that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcffed14ba84c38302a032e25ef525a9
https://doi.org/10.1158/0008-5472.c.6513925.v1
https://doi.org/10.1158/0008-5472.c.6513925.v1
Autor:
Vincent L. Reynolds, Wei Wang, Meredith A. Steeves, Javed A. Bhalli, LaRonda L Morford, Matthew M. Abernathy, Ronee B. Baracani
Publikováno v:
Burger's Medicinal Chemistry and Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c486d99f87c0a3f1a5278f5d9d2711a2
https://doi.org/10.1002/0471266949.bmc291
https://doi.org/10.1002/0471266949.bmc291
Autor:
Mario R. Fernandez, Franz X. Schaub, Chunying Yang, Weimin Li, Seongseok Yun, Stephanie K. Schaub, Frank C. Dorsey, Min Liu, Meredith A. Steeves, Andrea Ballabio, Alexandar Tzankov, Zhihua Chen, John M. Koomen, Anders E. Berglund, John L. Cleveland
Publikováno v:
Cancer Res
MYC family oncoproteins are regulators of metabolic reprogramming that sustains cancer cell anabolism. Normal cells adapt to nutrient-limiting conditions by activating autophagy, which is required for amino acid (AA) homeostasis. Here we report that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7d577df9794dbe175e5101ab7a646b
http://hdl.handle.net/11588/883838
http://hdl.handle.net/11588/883838
Autor:
Daniel P. Barry, M. Blanca Piazuelo, Meredith A. Steeves, Paula B. Luis, Dana M. Hardbower, Kshipra Singh, Claus Schneider, John L. Cleveland, Keith T. Wilson, Alain P. Gobert, Mohammad Asim, Chunying Yang
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Macrophage activation is a critical step in host responses during bacterial infections. Ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine metabolism, has been well studied in epithelial cells and is known to have essential roles in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f55b271398d9fcbe0848e88f28a3604
https://doi.org/10.1073/pnas.1614958114
https://doi.org/10.1073/pnas.1614958114
Autor:
Dan A. Dixon, John L. Cleveland, Joanne R. Doherty, Franz X. Schaub, Weimin Li, Meredith A. Steeves, Robert J. Rounbehler, Chunying Yang, Perry J. Blackshear, Mohammad Fallahi, Sandhya Sanduja
Publikováno v:
Cell. 150(3):563-574
SummaryMyc oncoproteins directly regulate transcription by binding to target genes, yet this only explains a fraction of the genes affected by Myc. mRNA turnover is controlled via AU-binding proteins (AUBPs) that recognize AU-rich elements (AREs) fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9bc6153215176304110bb1903f9ae05
Autor:
Frank C. Dorsey, Yasmine A. Valentin-Vega, Jacqueline Tait-Mulder, Douglas R. Green, Michael B. Kastan, Meredith A. Steeves, Kirsteen H. Maclean, Sandra Milasta, John L. Cleveland
Publikováno v:
Blood. 119:1490-1500
Ataxia-telangiectasia mutated (ATM) plays a central role in DNA damage responses, and its loss leads to development of T-cell malignancies. Here, we show that ATM loss also leads to intrinsic mitochondrial abnormalities in thymocytes, including eleva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b28c7fd9239f76e7c4a83e3ca0119a
https://doi.org/10.1182/blood-2011-08-373639
https://doi.org/10.1182/blood-2011-08-373639
Autor:
Kristie L. Rose, Der-Fen Suen, Ji Zhang, Mondira Kundu, Do Hyung Kim, Frank C. Dorsey, Chang Hwa Jung, Stephanie M. Prater, Joung Hyuck Joo, Kristin M. Hennessy-Walters, Meredith A. Steeves, Rekha Iyengar, John L. Cleveland, Craig B. Thompson, Kelly McCastlain, Chia Ying Yang, Richard J. Youle, Paul A. Ney, Aashish Joshi
Publikováno v:
Molecular Cell. 43(4):572-585
Autophagy, the primary recycling pathway of cells, plays a critical role in mitochondrial quality control under normal growth conditions and in the response to cellular stress. The Hsp90-Cdc37 chaperone complex coordinately regulates the activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c4d3e39a2f8ba4534ec4923f045eba