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pro vyhledávání: '"Meredith, Choquette"'
Autor:
Ming, Liu, Zhu-Li, Wan, Ying-Chi, Chu, Hassan, Aladdin, Birgit, Klaproth, Meredith, Choquette, Qing-Xin, Hua, Robert B, Mackin, J Sunil, Rao, Pierre, De Meyts, Panayotis G, Katsoyannis, Peter, Arvan, Michael A, Weiss
Publikováno v:
The Journal of biological chemistry. 284(50)
Protein evolution is constrained by folding efficiency ("foldability") and the implicit threat of toxic misfolding. A model is provided by proinsulin, whose misfolding is associated with beta-cell dysfunction and diabetes mellitus. An insulin analogu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa761fafe1cfdd7b8c6eb4ade08bd87e
https://pubmed.ncbi.nlm.nih.gov/19850922
https://pubmed.ncbi.nlm.nih.gov/19850922
