Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Meredith, Bond"'
Autor:
Maureen O Shanks, Linda M Lund, Sabrina Manni, Mary Russell, Joseph R H Mauban, Meredith Bond
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46316 (2012)
A-kinase anchoring proteins (AKAPs) bind the regulatory subunits of protein kinase A (PKA) and localize the holoenzyme to discrete signaling microdomains in multiple subcellular compartments. Despite emerging evidence for a nuclear pool of PKA that r
Externí odkaz:
https://doaj.org/article/64df94ec518b487bb9fdef2c271755e6
Autor:
G. Kwame Yankey, Christopher DeFilippi, Zhongjun J. Wu, Xufeng Wei, Tieluo Li, Ahmet Kilic, Meredith Bond, Gary Schwartzbauer, Bartley P. Griffith, Changfu Wu
Publikováno v:
International Journal of Cardiology. 166:158-165
The underlying molecular mechanisms of the remodeling after myocardial infarction (MI) remain unclear. The purpose of this study was to investigate the role of a survival pathway (PI3K/Akt) and an apoptosis pathway (calcineurin/BAD) in the remodeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a12dcab3d64b9de44a7030d86769e9
https://doi.org/10.1016/j.ijcard.2011.10.107
https://doi.org/10.1016/j.ijcard.2011.10.107
Autor:
Farhad Forudi, Bradley K. McConnell, James Bautista, Niladri Mal, Kwangdeok Lee, Meredith Bond, J.-P. Jin, Marc S. Penn, Raúl A. Schwartzman, Zoran B. Popović
Publikováno v:
Journal of Biological Chemistry. 284:1583-1592
Protein kinase A (PKA)-dependent phosphorylation is regulated by targeting of PKA to its substrate as a result of binding of regulatory subunit, R, to A-kinase-anchoring proteins (AKAPs). We investigated the effects of disrupting PKA targeting to AKA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf16eda86647db7551f0ca98d5ff54c6
https://doi.org/10.1074/jbc.m806321200
https://doi.org/10.1074/jbc.m806321200
Publikováno v:
Journal of Biological Chemistry. 283:24145-24154
Subcellular compartmentalization of the cAMP-dependent protein kinase (PKA) by protein kinase A-anchoring proteins (AKAPs) facilitates local protein phosphorylation. However, little is known about how PKA targeting to AKAPs is regulated in the intact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70dce700ae0910d0f778acb83839e457
https://doi.org/10.1074/jbc.m802278200
https://doi.org/10.1074/jbc.m802278200
Publikováno v:
The FASEB Journal. 29
Heart disease is the most frequent cause of death in man and becomes more common with age. Cardiomyopathies have been linked to changes in structural proteins, including intermediate filament (IF) ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49f2f7a183ab7df6cb24e9b810e3caee
https://doi.org/10.1096/fasebj.29.1_supplement.799.11
https://doi.org/10.1096/fasebj.29.1_supplement.799.11
Publikováno v:
Circulation Research. 96:401-411
Regulator of G-protein–signaling (RGS) proteins play a key role in the regulation of G-protein–coupled receptor (GPCR) signaling. The characteristic hallmark of RGS proteins is a conserved ≈120-aa RGS region that confers on these proteins the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0630b54b8056626a14ea92257d4f605
https://doi.org/10.1161/01.res.0000158287.49872.4e
https://doi.org/10.1161/01.res.0000158287.49872.4e
Publikováno v:
Journal of Biological Chemistry. 280:6602-6609
Besides the core structure conserved in all troponin I isoforms, cardiac troponin I (cTnI) has an N-terminal extension that contains phosphorylation sites for protein kinase A under beta-adrenergic regulation. A restricted cleavage of this N-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce2fe9c9c02a89329861a50ce9319a1
https://doi.org/10.1074/jbc.m408525200
https://doi.org/10.1074/jbc.m408525200
Publikováno v:
PROTEOMICS. 4:1505-1516
Altered expression of different classes of genes has been shown to differentiate between failing and nonfailing human hearts. However, characterization of proteins and the post-translational modifications that regulate their functions is required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06317cdc580f71dfda11c6de48104de3
https://doi.org/10.1002/pmic.200300682
https://doi.org/10.1002/pmic.200300682
Autor:
Alexandru Almasan, Patrick M. McCarthy, James B. Young, Sofia C. Masri, Mohamad H. Yamani, Jianbo Li, Norman B. Ratliff, Carolyn Apperson-Hansen, Randall C. Starling, Meredith Bond, Mary A. Russell, Jiacheng Yang
Publikováno v:
Transplantation. 76:859-864
Background. We investigated the occurrence of apoptosis during and after resolution of cardiac allograft rejection. Apoptosis could play different roles in graft survival depending on the target cells; thus, we also determined the cell types involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5e0686cbe14c9cd5a673ea15bda668a
https://doi.org/10.1097/01.tp.0000084824.70320.da
https://doi.org/10.1097/01.tp.0000084824.70320.da
Autor:
James B. Young, Carolina S. Masri, Mohamad H. Yamani, Randall C. Starling, Meredith Bond, E. Murat Tuzcu, Norman B. Ratliff, Patrick M. McCarthy
Publikováno v:
Journal of the American College of Cardiology. 39(5):804-810
Objectives This study was undertaken to test the hypothesis that transplant coronary vasculopathy (CV) is associated with increased myocardial protein expression of both tissue factor (TF) and integrin αvβ3. Background The vitronectin receptor (int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7520ee2ca0e713bd69157fe126f89938