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of 2
pro vyhledávání: '"Meredeth Shelley"'
Autor:
John W. Sweetenham, Deepa Jagadeesh, Meredeth Shelley, Brian J. Bolwell, Brian T. Hill, Mitchell R. Smith, Brad Pohlman, Robert M. Dean, Stephen D. Smith
Publikováno v:
Leukemia & Lymphoma. 59:690-694
B-cell non-Hodgkin lymphomas (NHL) display dysregulation of pathways controlling cell proliferation and apoptosis. Combined proteasome and mTOR inhibition, demonstrated with bortezomib and everolimus in a preclinical model, thus warrants evaluation i
Autor:
Robert M. Dean, Brian T. Hill, Mitchell R. Smith, Amy Healy, Janice Kakish, Stephen D. Smith, Brad Pohlman, Deepa Jagadeesh, Jeanie Wyckhouse, Jennifer Mears, Meredeth Shelley
Publikováno v:
Blood. 124:4482-4482
INTRODUCTION: Non-Hodgkin lymphomas (NHL) are characterized by dysregulation of pathways controlling cell proliferation and apoptosis. Proteosome inhibitors and mTOR inhibitors target these pathways and have single-agent activity in NHL, though their