Výsledky vyhledávání - "Mercy A. Thomas"

Akademický článek

CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers

Autor: Nour K. Majbour, Jan O. Aasly, Eldbjørg Hustad, Mercy A. Thomas, Nishant N. Vaikath, Naser Elkum, Wilma D. J. van de Berg, Takahiko Tokuda, Brit Mollenhauer, Henk W. Berendse, Omar M. A. El-Agnaf

Publikováno v: Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-10 (2020)

Abstract Background Asymptomatic carriers of leucine-rich repeat kinase 2 (LRRK2) gene mutations constitute an ideal population for discovering prodromal biomarkers of Parkinson’s disease (PD). In this study, we aim to identify CSF candidate risk b

Externí odkaz: https://doaj.org/article/ee5ec5df964e4d5e95f941a5372ac1af

Zobrazit plný text záznamu

Plný text ve formátu HTML

Cerebrospinal α-Synuclein Oligomers Reflect Disease Motor Severity in DeNoPa Longitudinal Cohort

Autor: Nour K, Majbour, Ilham Y, Abdi, Mohammed, Dakna, Tamara, Wicke, Elisabeth, Lang, Houda Y, Ali Moussa, Mercy A, Thomas, Claudia, Trenkwalder, Bared, Safieh-Garabedian, Takahiko, Tokuda, Brit, Mollenhauer, Omar, El-Agnaf

Publikováno v: Movement disorders : official journal of the Movement Disorder SocietyReferences. 36(9)

Tangible efforts have been made to identify biomarkers for Parkinson's disease (PD) diagnosis and progression, with α-synuclein (α-syn) related biomarkers being at the forefront.The objectives of this study were to explore whether cerebrospinal flu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2e1e44bf00a52260235ea4aee3685105
https://pubmed.ncbi.nlm.nih.gov/33978256

Zobrazit plný text záznamu

CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson's disease: a study in LRRK2 mutation carriers

Autor: Naser Elkum, Brit Mollenhauer, Nour K. Majbour, Henk W. Berendse, Nishant N. Vaikath, Jan O. Aasly, Wilma D.J. van de Berg, Eldbjørg Hustad, Mercy A. Thomas, Takahiko Tokuda, Omar M. A. El-Agnaf

Publikováno v: Majbour, N K, Aasly, J O, Hustad, E, Thomas, M A, Vaikath, N N, Elkum, N, Van De Berg, W D J, Tokuda, T, Mollenhauer, B, Berendse, H W & El-Agnaf, O M A 2020, ' CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson's disease : A study in LRRK2 mutation carriers ', Translational Neurodegeneration, vol. 9, no. 1, 15 . https://doi.org/10.1186/s40035-020-00192-4
Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-10 (2020)
Translational Neurodegeneration, 9(1):15. BioMed Central
Translational Neurodegeneration

Background Asymptomatic carriers of leucine-rich repeat kinase 2 (LRRK2) gene mutations constitute an ideal population for discovering prodromal biomarkers of Parkinson’s disease (PD). In this study, we aim to identify CSF candidate risk biomarkers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7707e836bbab831860ddb0e45042e560
https://research.vumc.nl/en/publications/34a8932a-77db-4202-943a-4243e65b8ed7

Zobrazit plný text záznamu

Additional file 1 of CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers

Autor: Majbour, Nour K., Aasly, Jan O., Hustad, Eldbjørg, Mercy A. Thomas, Nishant N. Vaikath, Elkum, Naser, Berg, Wilma D. J. Van De, Tokuda, Takahiko, Mollenhauer, Brit, Berendse, Henk W., El-Agnaf, Omar M. A.

Additional file 1: Supplementary Table 1. Associations between CSF biomarkers. No correlation between CSF biomarkers were present in symptomatic LRRK2 mutation carriers group alone. Both sPD and symptomatic LRRK2 mutation carriers groups were combine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8faaa8886835f8880f015c635d6f207a

Zobrazit plný text záznamu

Development of Novel Diagnostic and Therapeutic Tools for Parkinson's Diseases and Related Disorders

Autor: Mercy A. Thomas, Omar M. A. El-Agnaf, Muneera Fayyad, Nour K. Majbour, Nishant N. Vaikath

Publikováno v: Qatar Foundation Annual Research Conference Proceedings Volume 2018 Issue 2.

Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease. The biggest roadblock we are facing for the cure of PD is the lack of reliable biomarkers for the disease diagnosis or progression. This is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f16e909650fcd822783ab860742250cd
https://doi.org/10.5339/qfarc.2018.hbpd471

Zobrazit plný text záznamu

Abstract 4166: Role of calreticulin in the spontaneous development of lung adenocarcinoma: Evidence from a novel transgenic mouse model

Autor: Hamid Massaeli, Divya Viswanathan, Nasrin Mesaeli, Mercy Anna Thomas, Dhanya Pillai

Publikováno v: Cancer Research. 76:4166-4166

Lung cancer is the most common cause of cancer related deaths in both men and women worldiwide. The overall 5 year survival rate of lung cancer ranges between 5-15% (depending on the subtype). Based on histopathological criteria, lung cancer is subdi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::957fbf6bc0b9f9fdbf5a474a3b55169e
https://doi.org/10.1158/1538-7445.am2016-4166

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání