Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mercia P. Lima"'
Autor:
Mercia P. Lima, Maria Claudia Irigoyen, Rebeca Padrão Amorim, Ivana C. Moraes-Silva, Amanda Aparecida Ribeiro, Dulce Elena Casarini, Jorge L. Pesquero, Zaira Palomino, Leandro E. Souza
Publikováno v:
International Journal of Biological Macromolecules. 108:817-825
The (pro)renin receptor [(P)RR] has been implicated as a renin/prorenin receptor, and plays a role in local renin angiotensin system activation. Our goal was to investigate whether a transgenic mouse that expresses rat tonin [TGM'(rTon)] can regulate
Autor:
Amanda Aparecida Ribeiro, Dulce Elena Casarini, Zaira Palomino, João Bosco Pesquero, Maria C. Irigoyen, Jorge L. Pesquero, Daniele Ferreira, Leandro E. Souza, Mercia P. Lima
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 16 (2015)
Introduction: Tonin is an enzyme that is able to generate angiotensin II (Ang II) from angiotensin I (Ang I) or directly from angiotensinogen. Our goal was to characterize the renal renin-angiotensin system in transgenic mice that express rat tonin (
Autor:
Nélia Ferreira de Souza, Araujo Gw, Dos Santos Ivan Carlos, Mercia P. Lima, Meire Coelho de Almeida, Jorge L. Pesquero, Raquel Mariana de Melo Leite
Publikováno v:
Advances in Bioscience and Biotechnology. :96-104
Activin plays an important role in numerous physiological processes such as cell differentiation and remodeling, regeneration and repair of tissues from various organs, angiogenesis, morphogenesis of glandular organs, pluripotency and differentiation
Autor:
Alexandro de Lima Souza, Mercia P. Lima, Michael Bader, Daniela da Fonseca Pacheco, Igor D.G. Duarte, Jorge L. Pesquero, Andrea C. Perez, Cinthia Mara da Fonseca Pacheco
Publikováno v:
European Journal of Pharmacology. 713:1-5
Angiotensin II (Ang II) may be produced directly from angiotensinogen by tonin. Studies have demonstrated that Ang II and its metabolite Ang-(1-7) produce antinociception in pain animal models. The aim of the present study was to determine whether th
Autor:
Lucas Rios Drummond, Judson F. Quintão-Júnior, Mercia P. Lima, Antônio José Natali, Denis D. Damasceno, Daisy Fonseca Motta, Jorge L. Pesquero, Anderson J. Ferreira, Alvair P. Almeida
Publikováno v:
Regulatory Peptides. 181:30-36
In order to understand the mechanisms of interaction between tonin–angiotensin and renin–angiotensin systems (RAS) we evaluated, “in vivo” and “in vitro”, in Wistar rats, cardiovascular and electrocardiographic parameters after tonin admi
Autor:
Dulce Elena Casarini, Valéria Alves Fernades, Zaira Palomino Jara, Mercia P. Lima, Amanda Aparecida Ribeiro, Fernanda Rezende, Jorge L. Pesquero
Publikováno v:
New Aspects of the Renin Angiotensin System in Cardiovascular and Renal Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bd12da891b5fff8374e37e5fd9ddf9e
https://doi.org/10.2174/9781681083131116010011
https://doi.org/10.2174/9781681083131116010011
Autor:
Deoclécio Alves Chianca-Jr, Luciano Gonçalves Fernandes, Joelma Maria Cardoso Gomide, Luiz Gonzaga da Silva, Giselle Foureaux, Mercia P. Lima, Pedro Henrique de Amorim Miranda, Rodrigo Cunha Alvim de Menezes, Jorge L. Pesquero, Leonardo Máximo Cardoso, Anderson J. Ferreira, Fernanda Cacilda dos Santos Silva
Publikováno v:
Experimental Physiology. 98:57-66
New Findings • What is the central question of this study?Is the increase in blood pressure observed in rats fed a low protein diet due to overactivation of sympathetic and renin angiontensin systems? • What is the main finding and its importance
Autor:
Mirian Teresa Paz Lopes, Maria Aparecida Gomes, Valbert Nascimento Cardoso, Lucíola S. Barcelos, Mercia P. Lima, João Bosco Pesquero, Débora Ayame Higuchi, Mauro M. Teixeira, Vivian Nogueira Silbiger, Jorge L. Pesquero, Ronaldo C. Araujo, Dos Santos Ivan Carlos
Publikováno v:
Cancer Science. 101:453-459
To assess the importance of carbohydrate moieties to the anti-angiogenic activity of plasminogen fragments, we cloned the fragment corresponding to amino acids Val(79) to Thr(346) (Kint3-4) that presents the three glycosylation sites. The activity of
Autor:
Ronaldo Carvalho Araújo, João Bosco Pesquero, Marie Sumitani, Eliane S. L. Lomez, Jorge L. Pesquero, Mercia P. Lima, Michael Bader
Publikováno v:
Physiology & Behavior. 76:327-333
Tonins are serine proteinases mainly found in the rat submandibular gland, which are capable of generating the pressor octapeptide angiotensin II (Ang II) not only from the classical substrate angiotensin I but also from the synthetic tetradecapeptid
Autor:
Joelma M C, Gomide, Rodrigo C, de Menezes, Luciano G, Fernandes, Fernanda C, Silva, Leonardo M, Cardoso, Pedro H, Miranda, Luiz Gonzaga, da Silva, Mercia P, Lima, Jorge L, Pesquero, Giselle, Foureaux, Anderson J, Ferreira, Deoclécio A, Chianca
Publikováno v:
Experimental physiology. 98(1)
Previous studies have shown that postweaning protein restriction induces changes in the sympathetic nervous system in rats, leading to alterations in cardiovascular parameters. In addition, the renin-angiotensin system is also affected in these anima