Cancer cell adaptation to chemotherapy

Autor: Higgins Bernie, Toh Simon, Somers Shaw S, Johnson Penny, Di Palma Silvana, Glaysher Sharon, Fernando Augusta, Sharma Sanjay, Whitehouse Pauline A, Gabriel Francis G, Knight Louise A, Mercer Stuart J, Di Nicolantonio Federica, Lamont Alan, Gulliford Tim, Hurren Jeremy, Yiangou Constantinos, Cree Ian A

Publikováno v: BMC Cancer, Vol 5, Iss 1, p 78 (2005)

Abstract Background Tumor resistance to chemotherapy may be present at the beginning of treatment, develop during treatment, or become apparent on re-treatment of the patient. The mechanisms involved are usually inferred from experiments with cell li

Externí odkaz: https://doaj.org/article/cefcfe6e423c4cfd9ffa9f123f33f832

The in vitro effect of gefitinib ('Iressa') alone and in combination with cytotoxic chemotherapy on human solid tumours

Autor: Knight Louise A, Di Nicolantonio Federica, Whitehouse Pauline, Mercer Stuart, Sharma Sanjay, Glaysher Sharon, Johnson Penny, Cree Ian A

Publikováno v: BMC Cancer, Vol 4, Iss 1, p 83 (2004)

Abstract Background Activation of the epidermal growth factor receptor (EGFR) triggers downstream signaling pathways that regulate many cellular processes involved in tumour survival and growth. Gefitinib ('Iressa') is an orally active tyrosine kinas

Externí odkaz: https://doaj.org/article/2f30717cf9cb43fdbd1676ce8017120b

Emergency robotic colorectal surgery during the COVID-19 pandemic: A retrospective case series study

Autor: Maertens, Vicky, Stefan, Samuel, Rawlinson, Emma, Ball, Chris, Gibbs, Paul, Mercer, Stuart, Khan, Jim S.

Publikováno v: In Laparoscopic, Endoscopic and Robotic Surgery June 2022 5(2):57-60

Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial

Autor: Pearse, Rupert, Peden, Carol, Stephens, Tim, Bion, Julian, Martin, Graham, Thomson, Ann, Kahan, Brennan, Kerry, Sally, Rivett, Kate, Wells, Duncan, Richardson, Gerry, Brett, Stephen, Ackland, Gareth, Grocott, Mike, Holt, Peter, Robert, Glenn, Ukoumunne, Obioha, Waring, Justin, Everingham, Kirsty, Phull, Mandeep, Cromwell, David, Evley, Rachel, Lilford, Richard, Kocman, David, Asaria, Miqdad, Tarrant, Carolyn, Yang, Fan, Abraham, Ajit, Bothma, Pieter, Conway, Daniel, Stapleton, Clare, Edwards, Mark, Minto, Gary, Saunders, David, Owen, Tom, Waldmann, Carl, Hayden, Paul, Gillies, Michael, Tighe, Sean, Smith, Neil, Mythen, Monty, Murray, David, Lobo, Dileep, Leuwer, Martin, Kirk-Bayley, Justin, Howell, Simon, Gordon, Anthony, Anderson, Iain, Lourtie, Jose, Walker, Simon, Drake, Sharon, Murray, Dave, Watson, Nick, Szakmany, Tamas, Sutcliffe, Robert, Mahajan, Ravi, Girling, Alan, Forbes, Gordon, Faiz, Omar, Blunt, Mark, Singh, Surjait, Steel, Alistair, Wong, Kate, Cabreros, Leilani, Chitre, Vivek, Obideyi, Ayodele, Ali, Dhiraj, Blenk, Karl, Broad, Dan, Brodbeck, Andreas, Dumpala, Rajesh, Engel, Arnth, Ganepola, Ranjit, Garg, Sudha, Gay, Mike, Karlikowsk, Michael, Lams, Edward, Millican, Dean, Misane, Inga, Mull, Ajaya, Naik, Veena, Pushpa, Nathan, Nutt, Chris, Sagadai, Saravanna, Stuart, Hazel, Noble, Paul, Van De Velde, Niko, Hudson, Liam, Benlloch, Raoul, Singh, Satish, Verma, Karan, Laba, Damian, Carmichael, Jack, Richardson, Peter, Wilson, Graham, Lewis, Ricky, Surendran, Karthik, El-Damatty, Essam, Gurung, Sarada, Raulusaite, Ilona, Gerstina, Nabua, Rochester, Chloe, Kuldip, Rai, Lindner, Andrew, Murray, Therese, Vivek, Chitre, Lal, Roshan, Downey, Sarah, Velchuru, Vamsi, Aryal, Kamal, Guruswamy, Raman, Shankar, Kirosh, Porter, Helen, Tutton, Matthew, Agostini, Helen, Fletcher, Simon, Wharton, Richard, Hutchinson, Steve, Maiya, Bala, Howard-Griffin, Richard, Crabtree, Michael, Kushakovsky, Vlad, Omer, Abdel, Nadarajavan, Senthil, Bell, Stephanie, Patil, Vishal, Jah, Asif, Mahroof, Razeen, Watson, Nicholas, Tansley, John, Moncaster, Gareth, Flint, Neil, Miller, Andrew, Wood, Marcus, Prematie, Andreou, Roth, Sally, Bowery, Sarah, Hales, Dawn, Shah, Tanuja, Tierney, Gill, Morris, Craig, Iftikhar, Syed, Shukla, Amit, O'Dwyer, Grainne, Wolverson, Adam, Adams, Ferdinand, Perrin-Brown, Laura, White, Tim, Beavis, Sarah, Banks, Victoria, Abercrombie, John, Mole, Jonathon, Chana, Avninder, Banerjea, Ayan, Humes, David, Dhingsa, Rajpal, Wells, John, Brown, Stephanie, Adegoke, Kenneth, Tofte, Barclay, Alegria, Ana, Natarajan, Nat, Akhtar, Mansoor, Doughan, Samer, Mackinnon, John, Aravind, Biju, Cook, Esther, Snazelle, Mark, Gardner, Matt, Baldwin, Lee, Bailey, Simon, Lawton, Greg, Divekar, Nandita, Kukreja, Neil, Sange, Mansoor, Watson, Mark, Satisha, Mallikarjunappa, Protopapas, Michael, Belagodu, Zakaulla, Sarfi, Shameem, Raju, Pasupathy, Stacey, Brenda, Campbell-Smith, Tim, Parrington, Simon, Desikan, Somi, Brennan, Andrew, Griffith, John, Fletcher, Steve, Farrow, Catherine, Prestwich, Stewart, Graham, Laura, Northey, Martin, Gokhale, Jay, Mosley, Frances, Alexander, Peter, Sharma, Abhiram, Brady, Will, Hopper, John, Hill, Oliver, Varma, Sandeep, Macklin, Christopher, Rose, Alastair, Narula, Harjeet, Buckley, Sarah, Simeson, Karen, Sim, Kevin, Chadwick, Michael, Kuduvalli, Preeti, Dowling, Susan, McCairn, Amanda, Wilson, Lawrence, Vimalchandran, Dale, Jhamatt, Anita, Robin, Nicole, Monk, David, Bottomley, David, Zuzan, Oliver, Welters, Ingeborg, Ross-Anderson, Davina, Knowles, Charles, Bunker, Nick, Hu, Ying, Januszewska, Marta, Bodger, Phoebe, Niebrzegowska, Edyta, Correia, Carmen, Haslop, Richard, Abbott, Tom, Tanqueray, Tabitha, Wijeykoon, Sanjay, Jain, Susan, Full, Jens, Cuming, Tamzin, Bailey, Flora, Chatzimichail, Stelios, Cunha, Pedro, Rehman, Almas, Mohanty, Manab, Radford, Nicola, Mohr, Otto, Patel, Hitesh, Mateo, Dolores, Raj, Ashok, Machesney, Michael, Abdul, Nazar, Jemmet, Kim, Campbell, Marta, Inglis, David, Parker, Thomas, Medici, Thomas, Chan, Peter, Borgeaud, Nathan, Mukherjee, Dipankar, Odejinmi, Oluremi, Jovaisa, Tomas, Harwood, Elizabeth, Moonesinghe, Ramani, Mccullough, Jonathan, Modha, Jigna, Patel, Sanjiv, Limb, James, Bengeri, Sheshagiri, Rafi, Amir, Hall, Elizabeth, Brown, James, Gibson, Bruce, McNelis, Una, Bradburn, Mike, Lawson, Maria, Pick, Sara, Gaughan, Matthew, Browell, David, Linnett, Vanessa, Ritzema, Jenny, O'Loughlin, Paul, Cope, Sean, Corson, John, Roy, Alistair, Furneval, Julie, Holtham, Anitha, Noblett, Sophie, Dawson, Chris, McMenemie, Fiona, Pulsa, Stefan, Clement, Ian, Calder, Verity, Allen, Katherine, Rimmer, Catherine, Reed, Helen, Boyd, Christine, Monkhouse, Diane, Davies, Peter, Mullenheim, Jost, Cirstea, Emanuel, Cain, Martyn, Baillie, Kirsty, Bhowmick, Arnab, Jovestani, Keiarash, Mcmullan, Sean, Durant, Emma, Williams, Alexandra, Doyle, Donna, Cupitt, Jason, Barker, Jonathon, Harper, Nick, Brennan, Emma, Subar, Daren, Shawcross, Robert, Sebastian, Dominic, Patel, Panna, O'Connell, Gillian, Karvonen, Jyrki, Ishaan, Maitra, Hool, Alison, Burns, Karen, Mcarthur, Carol, Stergios, Tezas, Gursevak, Singh, Sonia, Makvana, Pratt, Heather, Lynne, Kaighan, McAfee, Sean, Lewis, Chris, Khalaf, Wael, Coldwell, Chris, Bronder, Christine, Wilkinson, Mark, Davis, Emma, Arnold, Glenn, Ziprin, Paul, Bartlett, Rachel, Stotz, Martin, D'souza, Rovan, Pemberton, Phillippa, Agarwal, Banwari, Sugavanam, Anita, Tan, Melanie, Varcada, Massimo, Lyness, Craig, Thorniley, Andrew, Prabhudesai, Ash, Griffin, Ruth, Vashisht, Shubha, Harris, James, Wakeford, Julie, Vaganov, Sergei, Mohsen, Yasser, Myers, Alister, Iqbal, Qamar, Harris, Simon, Ijaz, Sami, Burrow, James, Rubulotta, Francesca, El-Masry, Nabil, Stranix, Nicola, Rope, Tamsin, Liasis, Lampros, Husain, Tariq, Watfah, Josef, Griffiths, Megan, Warusavitarne, Janindra, Cartwright, Charles, Baxter, Linden, Visavadia, Rakhee, Sim, Malcolm, Wilson, Chris, Harrison, Paul, Williams, Dewi, Bews-Hair, Maria, Wrathall, Wayne, Jardine, Catherine, Mclaren, Paul, Dreyer, Fanus, Collins, Paddy, Edwards, Jennifer, Moug, Susan, Rooney, Kevin, Mcilveen, Erin, Henderson, Steven, Graham, Linda, Stark, Gail, Taylor, Lynn, Munro, Mark, Stewart, Lynn, Dickinson, Natalie, Rooney, Laura, Bailey, Lindsay, Murray, Diane, Geary, Tim, Gibson, Simon, Pow, Colin, Tan, Kerwei, Stevenson, Richard, Harrison, Ewen, Lamb, Peter, Carey, Kate, Fitton, Laura, Cook, Fabian, Schwarz, Magen, Morrison, Alan, Bryce, Gavin, Razouk, Khaled, Cain, Kathryn, Kunst, Gudrun, Papagrigoriadis, Savvas, Hopkins, Phil, Fawcet, Adrian, O'Carroll-Kuehn, Britta, Girgis, Amira, Janokowski, Stas, Farhat, Sami, Vig, Stella, Hadi, Nada, Parsons, Anthony, Cecconi, Maurizio, Melville, David, Hartopp, Richard, Woods, Justin, Karat, Isabella, Gerrard, David, Curtis, Edward, Somasekar, Krishnamurthy, Morgan-Jones, Tom, Martin, Michael, Henwood, Mark, Milne, Gordon, Sivasankaranand, Ajit, Scott, Alexandra, Escofet, Xavier, Toth-Tarsoly, Piroska, Al Shama, Majed, Hilton, Valerie, Davis, Huw, Williams, Gail, Harvard, Tim, Fitzgerald, Peter, Hurford, Dom, Muthuswamy, Babu, Williams, Gethin, Parry Jones, Jack, Mason, Nick, Rajagopal, Ramesh, Shenoy, Shrisha, Khater, Magdy, Morgan, Richard, Makris, Nikolaos, Hermandes, Anil, White, Andrew, Finch, Guy, Outram, Matt, Wilkinson, Jonny, Spimpolo, Jennifer, Shaw, Debbie, Obichere, Marion, Brescia, Giovanni, Menezes, Flavia, Stafford, Helena, Watters, Malcolm, Thorn, Chris, Stone, Julian, Andrews, Sam, Lythell, Nicola, Langton, Helen, Baxter, Stephen, Fernandes, Roy, Sunthareswaran, Rame, Ankers, Alastair, Panikkar, Kumar, Sleight, Simon, Cornforth, Belinda, Bell, Louise, Dodd, Phil, Welsh, Fenella, Watson, Geoff, Dorman, Frankie, Nash, Guy, Bromilow, James, Haigh, Fran, Pogson, David, Mercer, Stuart, Tucker, Vanessa, Way, Carolyn, Kirby-Bott, James, McLachan, Jenny, Chambers, Rob, Craven, Rachael, Blazeby, Jane, Freshwater-Turner, Dan, Burrows, Lorna, Howes, Helen, Christie, Iain, Coleman, Mark, Waddy, Sam, Sanders, Grant, Patrick, Abigail, Pitman, Catherine, Tyson, Susan, Smith, Hannah, Rousseau, Guy, Cartmell, Mark, Hanousek, Jan, Hollister, Nigel, Kightly, Lynsey, Pulletz, Mark, Talwar, Anjay, Baker, Susie, Thomas, Ruth, Gibbs, Richard, Noble, Hamish, Silsby, Joseph, Black, Helen, Evans, Thomas, DeBrunner, Robert, Cook, Nicola, Hodges, Stacy, Stevens, Amanda, Felipe, Rowena, Paddle, Jonathan, May, Denzil, Pickford, Alison, Riddington, Sid, Tucker, Olga, Smart, Simon, Marwick, Jeremy, Suggett, Nigel, Griffiths, Ewen, Riddington, David, Gill, Kathryn, Cruickshank, Neil, Susarla, Jay, Leno, Emma, Colley, Julie, Burtenshaw, Andrew, Lake, Stephen, Greenwood, Jamie, Bhardwaj, Sian, Thrush, Jessica, Wollaston, Julie, Sonksen, Julian, Patel, Rajan, Jennings, Adrian, Stanley, David, Wright, Jenny, Horner, Chris, Baig, Faisal, Cooke, Katie, Singh, Jagdeep, Claxton, Andrew, Mirza, Nazzia, Hester, Simon, Knight, Georgia, Kumar, Peeyush, Saran, Taj, Marangoni, Gabriele, Townsend, Roger, Thacker, Andy, Scase, Anne, Sharma, Meghna, Hale, Beth, Peden, Carol J, Kahan, Brennan C, Pearse, Rupert M ^*

Publikováno v: In The Lancet 1-7 June 2019 393(10187):2213-2221

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