Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Mercedes Robles-Díaz"'
Autor:
Sara Román-Sagüillo, Raisa Quiñones Castro, María Juárez-Fernández, Polina Soluyanova, Camilla Stephens, Mercedes Robles-Díaz, Francisco Jorquera Plaza, Javier González-Gallego, Susana Martínez-Flórez, María Victoria García-Mediavilla, Esther Nistal, Ramiro Jover, Sonia Sánchez-Campos
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6863 (2024)
Several hepatic disorders are influenced by gut microbiota, but its role in idiosyncratic drug-induced liver injury (iDILI), whose main causative agent is amoxicillin–clavulanate, remains unknown. This pioneering study aims to unravel particular pa
Externí odkaz:
https://doaj.org/article/02b7ecf5d3774efcb240879adfcd98a2
Autor:
Kodihalli C. Ravindra, Vishal S. Vaidya, Zhenyu Wang, Joel D. Federspiel, Richard Virgen-Slane, Robert A. Everley, Jane I. Grove, Camilla Stephens, Mireia F. Ocana, Mercedes Robles-Díaz, M. Isabel Lucena, Raul J. Andrade, Edmond Atallah, Alexander L. Gerbes, Sabine Weber, Helena Cortez-Pinto, Andrew J. Fowell, Hyder Hussaini, Einar S. Bjornsson, Janisha Patel, Guido Stirnimann, Sumita Verma, Ahmed M. Elsharkawy, William J. H. Griffiths, Craig Hyde, James W. Dear, Guruprasad P. Aithal, Shashi K. Ramaiah
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Diagnosis of rare, unpredictable, drug-induced liver injury (DILI) is a significant challenge for patients, clinicians, and drug development. Here, the authors discover, evaluate, and validate potential blood biomarkers to diagnose DILI and distingui
Externí odkaz:
https://doaj.org/article/ec3315a517864777bd5bdde19a8b8aa2
Autor:
Nelia Hernandez, Fernando Bessone, Daniela Chiodi, Manuel Mendizabal, A Sanchez, Ezequiel Ridruejo, Carla Bianchi, Carmen Pollio, Marco Arrese, María Isabel Schinoni, Vinicius Nunes, Raymundo Paraná, Edgardo Mengual, Maribel Lizárzabal, Inmaculada Medina-Caliz, Mercedes Robles-Díaz, Aida Ortega-Alonso, Raúl Andrade, María Isabel Lucena
Publikováno v:
Annals of Hepatology, Vol 28, Iss , Pp 101044- (2023)
Introduction and Objectives: Although amoxicillin-clavulanate combination (ACC) is a well-established cause of liver injury, clinicians are unaware of some aspects that explain why its diagnosis may be initially missed, making the patient susceptible
Externí odkaz:
https://doaj.org/article/608efa7c7ea44266b74830b001be983b
Autor:
Fernando Bessone, Nelia Hernandez, Raymundo Parana, Maria Isabel Schinoni, Manuel Mendizabal, Adriana Sanchez, Vinicius Nunes, Ezequiel Ridruejo, Daniela Schiodi, Eduardo Fassio, Hugo Tanno, Norberto Tamagnone, Martin Tagle, Pedro Montes, I Medina-Caliz, Mercedes Robles-Díaz, Aida Ortega-Alonso, Miren García-Cortes, Hao Niu, Ismael Alvarez-Alvarez, Rocío Romero-Flores, M Isabel Lucena, Raul J Andrade
Publikováno v:
Annals of Hepatology, Vol 28, Iss , Pp 101046- (2023)
Introduction and Objectives: Idiosyncratic drug-induced liver injury (DILI) caused by antineoplastic and biological agents is an emerging clinical burden in oncologic patients. However, clinical characteristics of DILI due to these drugs remain poorl
Externí odkaz:
https://doaj.org/article/f9a897e6934d4bf1926a564a971adc9c
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/e36e093364fc4e28bf4669b9dab92329
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Introduction: Apart from cessation of the implicated agent leading to drug-induced liver injury (DILI), there is no standard therapy for DILI. Corticosteroids have been used in DILI, although their efficacy is unclear. Published data showed either be
Externí odkaz:
https://doaj.org/article/524f5c23bb214c15a888f6d8b694c58d
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Introduction: Treatment is generally not available for drug-induced liver injury (DILI) patients except in some specific circumstances. The management of DILI is based on the withdrawal of the responsible drug and monitoring the patients and only a f
Externí odkaz:
https://doaj.org/article/06aa92194f4845fa851fba6d028e064d
Autor:
Fernando Bessone, Nelia Hernandez, Raymundo Parana, Manuel Mendizabal, Adriana Sanchez, Vinicius Nunes, Ezequiel Ridruejo, Daniela Schiodi, Genario Santos, Eduardo Fassio, Schinoni Maria I., Hugo Tanno, Martin Tagle, Pedro Montes, Marco Arrese, Nahum Mendez-Sanchez, Javier Brahm, Marcos Girala, Isabel Lizarzábal M., Edgardo Mengual, Enrique Carrera, Fernando Contreras, Inmaculada Medina-Caliz, Mercedes Robles-Díaz, Aida Ortega-Alonso, Miren García-Cortes, Ismael Alvarez-Alvarez, Hao Niu, Elvira Bonilla, Isabel Lucena M., Andrade Raul J.
Publikováno v:
Annals of Hepatology, Vol 24, Iss , Pp 100515- (2021)
Introduction: In 2011, the Latin-American DILI-Network (LATINDILIN) set up under the guidance of the Spanish DILI Registry a network of hepatologists to prospectively identify and characterize DILI patients. Aim: To evaluate the drugs more frequently
Externí odkaz:
https://doaj.org/article/23e653d90e874e32a99531a1bb80ad74
Autor:
Emilia V. Perdices, Inmaculada Medina-Cáliz, Sofía Hernando, Aida Ortega, Francisca Martín-Ocaña, José M. Navarro, Gloria Peláez, Agustín Castiella, Hacibe Hallal, Manuel Romero-Gómez, Andrés González-Jiménez, Mercedes Robles-Díaz, M.ª Isabel Lucena, Raúl J. Andrade
Publikováno v:
Revista Espanola de Enfermedades Digestivas, Vol 106, Iss 4, Pp 246-254 (2014)
Objectives: The hepatotoxic potential of statins is controversial. The objectives of this study were to describe the relative frequency of hepatotoxicity caused by statins and the phenotypes found in Spain. Patients and methods: The incidence of hepa
Externí odkaz:
https://doaj.org/article/4ebf40e688664e0487d9e5aae2ce7af9
Autor:
Mercedes Robles-Díaz, Inmaculada Medina-Caliz, Camilla Stephens, Raúl J Andrade, M Isabel Lucena
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Despite being relatively rare, drug-induced liver injury (DILI) is a serious condition, both for the individual patient due to the risk of acute liver failure, and for the drug development industry and regulatory agencies due to associations with dru
Externí odkaz:
https://doaj.org/article/08ae8ca934524ccf83a916635854214a