Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Mercedes Arnés"'
1
Akademický článek
Amyloid β42 peptide is toxic to non-neural cells in Drosophila yielding a characteristic metabolite profile and the effect can be suppressed by PI3K
Autor: Mercedes Arnés, Sergio Casas-Tintó, Anders Malmendal, Alberto Ferrús
Publikováno v: Biology Open, Vol 6, Iss 11, Pp 1664-1671 (2017)
The human Aβ42 peptide is associated with Alzheimer's disease through its deleterious effects in neurons. Expressing the human peptide in adult Drosophila in a tissue- and time-controlled manner, we show that Aβ42 is also toxic in non-neural cells,
Externí odkaz: https://doaj.org/article/15c2072a2e1c449883727e66688de944
Zobrazit plný text záznamu
2
Akademický článek
Drosophila enhancer-Gal4 lines show ectopic expression during development
Autor: Sergio Casas-Tintó, Mercedes Arnés, Alberto Ferrús
Publikováno v: Royal Society Open Science, Vol 4, Iss 3 (2017)
In Drosophila melanogaster the most widely used technique to drive gene expression is the binary UAS/Gal4 system. We show here that a set of nervous system specific enhancers (elav, D42/Toll-6, OK6/RapGAP1) display ectopic activity in epithelial tiss
Externí odkaz: https://doaj.org/article/f6e1bfcf98114ffe81aa70256d0c2257
Zobrazit plný text záznamu
3
3D Particle Tracking for Noninvasive In Vivo Analysis of Synaptic Microtubule Dynamics in Dendrites and Neuromuscular Junctions of Drosophila
Autor: Vivian T. Chou, Kamal Obbad, James S. J. Lee, Hideki Sasaki, Michael W. M. Jones, Hunkar Gizem Yesilyurt, David Van Vactor, Sam V Alworth, Luciano A. G. Lucas, Hoyin Lai, Mercedes Arnés, Jennifer B. Long
Publikováno v: Journal of visualized experiments : JoVE. (159)
Microtubules (MTs) play critical roles in neuronal development, but many questions remain about the molecular mechanisms of their regulation and function. Furthermore, despite progress in understanding postsynaptic MTs, much less is known about the c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f36a3dc9e69e5c479795d49fd283bc1
https://pubmed.ncbi.nlm.nih.gov/32478717
Zobrazit plný text záznamu
4
Amyloid β42 peptide is toxic to non-neural cells in Drosophila yielding a characteristic metabolite profile and the effect can be suppressed by PI3K
Autor: Sergio Casas-Tintó, Anders Malmendal, Mercedes Arnés, Alberto Ferrús
Publikováno v: Biology Open
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biology Open, Vol 6, Iss 11, Pp 1664-1671 (2017)
The human Aβ42 peptide is associated with Alzheimer's disease through its deleterious effects in neurons. Expressing the human peptide in adult Drosophila in a tissue- and time-controlled manner, we show that Aβ42 is also toxic in non-neural cells,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e87782d527c915ec4e4b19edff1cc36
http://europepmc.org/articles/PMC5703620
Zobrazit plný text záznamu
6
PI3K activation prevents Aβ42-induced synapse loss and favors insoluble amyloid deposits formation
Autor: Ninovska Romero, Mercedes Arnés, Sergio Casas-Tintó, Alberto Ferrús, Angel Acebes
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Biology of the Cell
Excess of Aβ42 peptide is considered a hallmark of the disease. Here we express the human Aβ42 peptide to assay the neuroprotective effects of PI3K in adult Drosophila melanogaster. The neuronal expression of the human peptide elicits progressive t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7054e2b345443275fe55b062a41e8e
Zobrazit plný text záznamu
7
MiR-219 deficiency in Alzheimer’s disease contributes to neurodegeneration and memory dysfunction through post-transcriptional regulation of tau-kinase network
Autor: Lannes J, Yoon A. Kim, Joshua D. Cho, Brian D. McCabe, Mercedes Arnés, Ismael Santa-Maria, Maria E. Alaniz
Intracellular accumulation of hyperphosphorylated misfolded tau proteins is one of the main neuropathological hallmarks in Alzheimer’s disease (AD) and related tauopathies. Hence, knowledge and understanding of disease mechanisms altering tau prote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37032909bb639ceeba9c7682cb001a94
Zobrazit plný text záznamu
9
Drosophila enhancer-Gal4 lines show ectopic expression during development
Autor: Alberto Ferrús, Sergio Casas-Tintó, Mercedes Arnés
Publikováno v: Royal Society Open Science
Digital.CSIC. Repositorio Institucional del CSIC
instname
Royal Society Open Science, Vol 4, Iss 3 (2017)
In Drosophila melanogaster the most widely used technique to drive gene expression is the binary UAS/Gal4 system. We show here that a set of nervous system specific enhancers (elav, D42/Toll-6, OK6/RapGAP1) display ectopic activity in epithelial tiss
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f817243c8569f81329875ecb60cd0e62
http://europepmc.org/articles/PMC5383858
Zobrazit plný text záznamu
10
Aberrant Wnt signaling: a special focus in CNS diseases
Autor: Sergio Casas Tinto, Mercedes Arnés
Wnt signals regulate cell proliferation, migration and differentiation during development, as well as synaptic transmission and plasticity in the adult brain. Abnormal Wnt signaling is central to a number of brain pathologies. We review here, the sig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afcdc7a0981f71d7ac795df82e2bd5e
http://hdl.handle.net/10261/200477
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje