Vesicular nanostructures composed of oleic acid and phosphatidylcholine: Effect of pH and molar ratio

Autor: Mercedes Cócera, Verónica Moner, Kirian Talló, M. De Cabo, Olga López

Publikováno v: Chemistry and Physics of Lipids. 213:96-101

Phospholipids and fatty acids are the main building blocks of biological membranes. Oleic acid is a monounsaturated omega-9 fatty acid commonly found in many natural sources. Its characteristic kinked structure grants this molecule with a great numbe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50edad8b2578a984ac8a43426b3b4d6
https://doi.org/10.1016/j.chemphyslip.2018.04.002

Sorption-desorption test for functional assessment of skin treated with a lipid system that mimics epidermal lamellar bodies

Autor: Estibalitz Fernández, Alfonso del Pozo, Mercedes Cócera, Olga López, Alfonso de la Maza, Verónica Moner, Gelen Rodríguez

Publikováno v: Contact Dermatitis. 77:25-34

SummaryBackground Many skin diseases are associated with either increases or decreases in lamellar body secretion, or dysfunctional lamellar bodies. Consequently, diseased skin is characterized by reduced barrier function and altered lipid compositio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::536fc727519bcb12808c819f42ad2196
https://doi.org/10.1111/cod.12771

Lamellar body mimetic system: An up-to-down repairing strategy of the stratum corneum lipid structure

Autor: Gelen Rodríguez, Verónica Moner, Alfonso de la Maza, Mercedes Cócera, Lucyanna Barbosa-Barros, Estibalitz Fernández, Olga López

Publikováno v: International Journal of Pharmaceutics. 510:135-143

Epidermal lamellar bodies (LBs) are organelles that secrete their content, mainly lipids and enzymes, into the intercorneocyte space of the stratum corneum (SC) to form the lamellar structure of this tissue. Thus, LBs have a key role in permeability

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aed6dac3a77543b30c5773a0c094815
https://doi.org/10.1016/j.ijpharm.2016.06.033

Monitoring bicosomes containing antioxidants in normal and irradiated skin

Autor: Alfonso de la Maza, Mercedes Cócera, Clotilde Policar, Sarah Hostachy, Estibalitz Fernández, Sylvain Clède, Christophe Sandt, Hélène Bertrand, Gelen Rodríguez, François Lambert, Olga López

Publikováno v: RSC Advances
RSC Advances, 2016, 6 (76), pp.72559-72567. ⟨10.1039/C6RA11170J⟩
RSC Advances, Royal Society of Chemistry, 2016, 6 (76), pp.72559-72567. ⟨10.1039/C6RA11170J⟩

This study evaluates the penetration of bicosome systems incorporating two different antioxidants into normal skin and skin exposed to ultraviolet-visible radiation (UV-VIS) by Fourier-transform infrared microspectroscopy (FT-IR) using synchrotron ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3dbb52db249d2ca4fc598b8f224b48d
https://doi.org/10.1039/c6ra11170j

Bicelles and bicosomes as free radical scavengers in the skin

Autor: Alfonso de la Maza, Lluís Fajarí, Gelen Rodríguez, Olga López, Mercedes Cócera, Estibalitz Fernández, Lucyanna Barbosa-Barros, Carmen López-Iglesias

Publikováno v: RSC Adv.. 4:53109-53121

In the present work, β-carotene antioxidant was incorporated in two different lipid nanoaggregates, bicelles and bicosomes, and its effectiveness against free radical formation in porcine skin in vitro was determined using 5,5-dimethyl-1-pyrroline-N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf406487c9393d1c239907563b0471c2
https://doi.org/10.1039/c4ra05157b