Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mercé Carmona"'
Autor:
Maribel Marquina, Eva Lambea, Mercé Carmona, Marta Sánchez-Marinas, Sandra López-Aviles, José Ayte, Elena Hidalgo, Rosa Aligue
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The fission yeast mitogen-activated kinase (MAPK) Sty1 is essential for cell survival in response to different environmental insults. In unstimulated cells, Sty1 forms an inactive ternary cytoplasmatic complex with the MAPKK Wis1 and the MAP
Externí odkaz:
https://doaj.org/article/e0ab4fd062ad49d6810124cb31b60fd6
Autor:
Clàudia Salat-Canela, Mercè Carmona, Rebeca Martín-García, Pilar Pérez, José Ayté, Elena Hidalgo
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109951- (2021)
Summary: Cdc42 GTPase rules cell polarity and growth in fission yeast. It is negatively and positively regulated by GTPase-activating proteins (GAPs) and guanine nucleotide exchange factors (GEFs), respectively. Active Cdc42-GTP localizes to the pole
Externí odkaz:
https://doaj.org/article/6387bfcfd2c149ada5f5a78fed45275b
Autor:
Mercè Carmona, Laura de Cubas, Eric Bautista, Marta Moral-Blanch, Iria Medraño-Fernández, Roberto Sitia, Susanna Boronat, José Ayté, Elena Hidalgo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Reliable methods of measuring intracellular H2O2 fluctuations are necessary to advance redox biology. Here the authors design a H2O2 sensor based on the fission yeast peroxiredoxin Tpx1 to sense nanomolar fluctuations of intracellular H2O2 in respons
Externí odkaz:
https://doaj.org/article/aafcb8e611bf4afab90ca09a171dc392
Autor:
Susanna Boronat, Alba Domènech, Mercè Carmona, Sarela García-Santamarina, M Carmen Bañó, José Ayté, Elena Hidalgo
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006858 (2017)
The thioredoxin and glutaredoxin pathways are responsible of recycling several enzymes which undergo intramolecular disulfide bond formation as part of their catalytic cycles such as the peroxide scavengers peroxiredoxins or the enzyme ribonucleotide
Externí odkaz:
https://doaj.org/article/2438248c6f0d476d98d63faab1899574
Autor:
Susanna Boronat, Alba Domènech, Esther Paulo, Isabel A. Calvo, Sarela García-Santamarina, Patricia García, Javier Encinar del Dedo, Anna Barcons, Erica Serrano, Mercè Carmona, Elena Hidalgo
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 395-399 (2014)
Cysteine residues, and in particular their thiolate groups, react not only with reactive oxygen species but also with electrophiles and with reactive nitrogen species. Thus, cysteine oxidation has often been linked to the toxic effects of some of the
Externí odkaz:
https://doaj.org/article/705108d7f2a04e168fb259dcee159e25
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005106 (2015)
Iron is an essential cofactor, but it is also toxic at high levels. In Schizosaccharomyces pombe, the sensor glutaredoxin Grx4 guides the activity of the repressors Php4 and Fep1 to mediate a complex transcriptional response to iron deprivation: acti
Externí odkaz:
https://doaj.org/article/18df53c9482242e4b00d0326494a3101
Autor:
Jose A. Cancelas, Mercé Carmona, Javier Briones, Ana Limón, Margarita Nadal, Joan Garcia, Félix Rueda, Teresa Puig, Oscar Fornas, Jordi Barquinero
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Retroviral vectors constitute the most efficient system to deliver and integrate foreign genes into mammalian cells. We have developed a producer cell line that yields high titers of amphotropic retroviral vectors carrying the enhanced green fluoresc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9bdb43f9f67a09260038209b219760
http://www.scopus.com/inward/record.url?eid=2-s2.0-0030780644&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0030780644&partnerID=MN8TOARS
Publikováno v:
Analytical Cellular Pathology, Vol 14, Iss 3, Pp 129-140 (1997)
Cellular drug resistance, which involves several mechanisms such as P‐glycoprotein (P‐gp) overexpression, kinetic and metabolic quiescence, or the increase in the intracellular levels of glutathione, limits the effectiveness of cancer treatment.
Externí odkaz:
https://doaj.org/article/7a65d525276a4455b382169315422b91
Autor:
Jorge Fernández-Vázquez, Itzel Vargas-Pérez, Miriam Sansó, Karin Buhne, Mercè Carmona, Esther Paulo, Damien Hermand, Miguel Rodríguez-Gabriel, José Ayté, Sebastian Leidel, Elena Hidalgo
Publikováno v:
PLoS Genetics, Vol 9, Iss 7, p e1003647 (2013)
The Elongator complex, including the histone acetyl transferase Sin3/Elp3, was isolated as an RNA polymerase II-interacting complex, and cells deficient in Elongator subunits display transcriptional defects. However, it has also been shown that Elong
Externí odkaz:
https://doaj.org/article/b23a589a96094f04a8dcccbc61fd1b8b