Výsledky vyhledávání - "Mercè Gomar-Alba"

Akademický článek

Budding yeast complete DNA synthesis after chromosome segregation begins

Autor: Tsvetomira Ivanova, Michael Maier, Alsu Missarova, Céline Ziegler-Birling, Monica Dam, Mercè Gomar-Alba, Lucas B. Carey, Manuel Mendoza

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

In the S phase of the cell cycle, the full genome needs to be replicated before cell division occurs. Here, authors show that in budding yeast DNA synthesis is completed after chromosome segregation begins.

Externí odkaz: https://doaj.org/article/73793fef25754534b0d83a92650d5b5a

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Akademický článek

Modulation of Cell Identity by Modification of Nuclear Pore Complexes

Autor: Mercè Gomar-Alba, Manuel Mendoza

Publikováno v: Frontiers in Genetics, Vol 10 (2020)

Nuclear pore complexes (NPCs) are protein assemblies that form channels across the nuclear envelope to mediate communication between the nucleus and the cytoplasm. Additionally, NPCs interact with chromatin and influence the position and expression o

Externí odkaz: https://doaj.org/article/59090877902b433587f3932fb14f6322

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Akademický článek

The CWI Pathway: A Versatile Toolbox to Arrest Cell-Cycle Progression

Autor: Inma Quilis, Mercè Gomar-Alba, Juan Carlos Igual

Publikováno v: Journal of Fungi, Vol 7, Iss 12, p 1041 (2021)

Cell-signaling pathways are essential for cells to respond and adapt to changes in their environmental conditions. The cell-wall integrity (CWI) pathway of Saccharomyces cerevisiae is activated by environmental stresses, compounds, and morphogenetic

Externí odkaz: https://doaj.org/article/3e251c54aed84fcba3ba1f8d92c82942

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Akademický článek

Whi7 is an unstable cell-cycle repressor of the Start transcriptional program

Autor: Mercè Gomar-Alba, Ester Méndez, Inma Quilis, M. Carmen Bañó, J. Carlos Igual

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

The commitment of cells to a new cycle of division involves inactivation of the Start transcriptional repressor Whi5. Here the authors show that the sequence related protein Whi7 associates to G1/S gene promoters in late G1 and collaborates with Whi5

Externí odkaz: https://doaj.org/article/b966a4d634224d4cbbbf5c5d656feae2

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Nuclear pore complex acetylation regulates mRNA export and cell cycle commitment in budding yeast

Autor: Mercè Gomar‐Alba, Vasilisa Pozharskaia, Bogdan Cichocki, Celia Schaal, Arun Kumar, Basile Jacquel, Gilles Charvin, J Carlos Igual, Manuel Mendoza

Publikováno v: EMBO Journal
EMBO Journal, 2022, ⟨10.15252/embj.2021110271⟩

Nuclear pore complexes (NPCs) mediate communication between the nucleus and the cytoplasm, and regulate gene expression by interacting with transcription and mRNA export factors. Lysine acetyltransferases (KATs) promote transcription through acetylat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819be62ba6ee6be7b191072289ea33e1
https://pubmed.ncbi.nlm.nih.gov/35735140

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Author Reply to Peer Reviews of Nuclear Pore Complex Acetylation Regulates mRNA Export and Cell Cycle Commitment in Budding Yeast

Autor: Manuel Mendoza, J. Carlos Igual, Gilles Charvin, Basile Jacquel, Arun Kumar, Celia Schaal, Vasilisa Pozharskaia, Mercè Gomar-Alba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a68124def14a0214d041c15d4a880f2b
https://doi.org/10.15252/rc.2022169060

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Nuclear Pore Complex Acetylation Regulates mRNA Export and Cell Cycle Commitment in Budding Yeast

Autor: Mercè Gomar-Alba, Celia Schaal, Arun Kumar, Basile Jacquel, Gilles Charvin, J. Carlos Igual, Vasilisa Pozharskaia, Manuel Mendoza

Nuclear pore complexes (NPCs) mediate communication between the nucleus and the cytoplasm and regulate gene expression by interacting with transcription and mRNA export factors. Lysine acetyl-transferases (KATs) promote transcription through acetylat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a14ccd68356236e501ff54d0735153
https://hal.archives-ouvertes.fr/hal-03420807

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The budding yeast Start repressor Whi7 differs in regulation from Whi5, emerging as a major cell cycle brake in response to stress

Autor: Ester Méndez, Manuel Mendoza, Mercè Gomar-Alba, J. Carlos Igual, M. Carmen Bañó, Inma Quilis

Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2020, 133 (24), ⟨10.1242/jcs.251413⟩
Journal of Cell Science, 2020, 133 (24), ⟨10.1242/jcs.251413⟩
Méndez Belinchón, Ester Gomar Alba, Mercè Bañó Aracil, María del Carmen Mendoza, Manuel Quilis Bayarri, Inmaculada Igual García, Juan Carlos 2020 The budding yeast Start repressor Whi7 differs in regulation from Whi5, emerging as a major cell cycle brake in response to stress Journal of Cell Science 133 24
RODERIC. Repositorio Institucional de la Universitat de Valéncia
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RODERIC: Repositorio Institucional de la Universitat de Valéncia
article-version (VoR) Version of Record

Start is the main decision point in the eukaryotic cell cycle at which cells commit to a new round of cell division. It involves the irreversible activation of a transcriptional programme through the inactivation of Start transcriptional repressors:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424d86db340e2080ea55f54ad1713666
https://hal.archives-ouvertes.fr/hal-03420810

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Impact of Chromosome Fusions on 3D Genome Organization and Gene Expression in Budding Yeast

Autor: Marc A. Marti-Renom, Davide Baù, Manuel Mendoza, Francesca Di Giovanni, Vasilisa Pozharskaia, Mercè Gomar-Alba, Lucas B. Carey, Marco Di Stefano

Publikováno v: Genetics
Genetics, 2020, 214 (3), pp.651-667. ⟨10.1534/genetics.119.302978⟩
Genetics, Oxford University Press, 2020, 214 (3), pp.651-667. ⟨10.1534/genetics.119.302978⟩

In eukaryotic cells, the spatial organization of genes within the nucleus is correlated with their expression. However, correlation is not causa-tion. To determine how nuclear spatial organization affects gene expression, Di Stefano et al. studied...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8195b268e76ac76aa1a1f769dc0ba7a
https://hal.science/hal-03420822

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Whi7 is an unstable cell-cycle repressor of the Start transcriptional program

Autor: Ester Méndez, Mercè Gomar-Alba, M. Carmen Bañó, J. Carlos Igual, Inma Quilis

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications

Start is the main decision point in eukaryotic cell cycle in which cells commit to a new round of cell division. It involves the irreversible activation of a transcriptional program by G1 CDK-cyclin complexes through the inactivation of Start transcr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992c17891b0c4e1182429aae96e2e74a
https://doaj.org/article/b966a4d634224d4cbbbf5c5d656feae2

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