Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mercè, Carmona"'
Autor:
Clàudia Salat-Canela, Mercè Carmona, Rebeca Martín-García, Pilar Pérez, José Ayté, Elena Hidalgo
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109951- (2021)
Summary: Cdc42 GTPase rules cell polarity and growth in fission yeast. It is negatively and positively regulated by GTPase-activating proteins (GAPs) and guanine nucleotide exchange factors (GEFs), respectively. Active Cdc42-GTP localizes to the pole
Externí odkaz:
https://doaj.org/article/6387bfcfd2c149ada5f5a78fed45275b
Autor:
Mercè Carmona, Laura de Cubas, Eric Bautista, Marta Moral-Blanch, Iria Medraño-Fernández, Roberto Sitia, Susanna Boronat, José Ayté, Elena Hidalgo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Reliable methods of measuring intracellular H2O2 fluctuations are necessary to advance redox biology. Here the authors design a H2O2 sensor based on the fission yeast peroxiredoxin Tpx1 to sense nanomolar fluctuations of intracellular H2O2 in respons
Externí odkaz:
https://doaj.org/article/aafcb8e611bf4afab90ca09a171dc392
Autor:
Susanna Boronat, Alba Domènech, Mercè Carmona, Sarela García-Santamarina, M Carmen Bañó, José Ayté, Elena Hidalgo
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006858 (2017)
The thioredoxin and glutaredoxin pathways are responsible of recycling several enzymes which undergo intramolecular disulfide bond formation as part of their catalytic cycles such as the peroxide scavengers peroxiredoxins or the enzyme ribonucleotide
Externí odkaz:
https://doaj.org/article/2438248c6f0d476d98d63faab1899574
Autor:
Susanna Boronat, Alba Domènech, Esther Paulo, Isabel A. Calvo, Sarela García-Santamarina, Patricia García, Javier Encinar del Dedo, Anna Barcons, Erica Serrano, Mercè Carmona, Elena Hidalgo
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 395-399 (2014)
Cysteine residues, and in particular their thiolate groups, react not only with reactive oxygen species but also with electrophiles and with reactive nitrogen species. Thus, cysteine oxidation has often been linked to the toxic effects of some of the
Externí odkaz:
https://doaj.org/article/705108d7f2a04e168fb259dcee159e25
Autor:
José Carlos Montañés, Marta Huertas, Simone G. Moro, William R. Blevins, Mercè Carmona, José Ayté, Elena Hidalgo, M. Mar Albà
Publikováno v:
Genome research.
The unicellular yeast Schizosaccharomyces pombe (fission yeast) retains many of the splicing features observed in humans and is thus an excellent model to study the basic mechanisms of splicing. Nearly half the genes contain introns, but the impact o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2729f2926b57c9241ccb918cd8d33ef
https://pubmed.ncbi.nlm.nih.gov/35618415
https://pubmed.ncbi.nlm.nih.gov/35618415
Autor:
Pilar Pérez, Clàudia Salat-Canela, Elena Hidalgo, Rebeca Martín-García, Mercè Carmona, José Ayté
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109951-(2021)
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
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Cdc42 GTPase rules cell polarity and growth in fission yeast. It is negatively and positively regulated by GTPase-activating proteins (GAPs) and guanine nucleotide exchange factors (GEFs), respectively. Active Cdc42-GTP localizes to the poles, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feba3b409ec407ba3ba715555558a30a
http://www.sciencedirect.com/science/article/pii/S2211124721014285
http://www.sciencedirect.com/science/article/pii/S2211124721014285
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005106 (2015)
Iron is an essential cofactor, but it is also toxic at high levels. In Schizosaccharomyces pombe, the sensor glutaredoxin Grx4 guides the activity of the repressors Php4 and Fep1 to mediate a complex transcriptional response to iron deprivation: acti
Externí odkaz:
https://doaj.org/article/18df53c9482242e4b00d0326494a3101
Autor:
Rebeca Martín-García, José Ayté, Clàudia Salat-Canela, Elena Hidalgo, Pilar Pérez, Mercè Carmona
Cdc42 rules cell polarity and growth in fission yeast. It is negatively and positively regulated by GTPase-activating proteins (GAPs) and by Guanine nucleotide Exchange factors (GEFs), respectively. Active Cdc42-GTP localizes to the poles, where it a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c448bcbd1583ab0c8d06bed5653065f
https://doi.org/10.1101/2021.08.10.455852
https://doi.org/10.1101/2021.08.10.455852
Publikováno v:
Analytical Cellular Pathology, Vol 14, Iss 3, Pp 129-140 (1997)
Cellular drug resistance, which involves several mechanisms such as P‐glycoprotein (P‐gp) overexpression, kinetic and metabolic quiescence, or the increase in the intracellular levels of glutathione, limits the effectiveness of cancer treatment.
Externí odkaz:
https://doaj.org/article/7a65d525276a4455b382169315422b91
Autor:
Jorge Fernández-Vázquez, Itzel Vargas-Pérez, Miriam Sansó, Karin Buhne, Mercè Carmona, Esther Paulo, Damien Hermand, Miguel Rodríguez-Gabriel, José Ayté, Sebastian Leidel, Elena Hidalgo
Publikováno v:
PLoS Genetics, Vol 9, Iss 7, p e1003647 (2013)
The Elongator complex, including the histone acetyl transferase Sin3/Elp3, was isolated as an RNA polymerase II-interacting complex, and cells deficient in Elongator subunits display transcriptional defects. However, it has also been shown that Elong
Externí odkaz:
https://doaj.org/article/b23a589a96094f04a8dcccbc61fd1b8b