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pro vyhledávání: '"Merav Tauber"'
Autor:
Merav Tauber, Yair Ben-Chaim
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5295 (2024)
Some signaling processes mediated by G protein-coupled receptors (GPCRs) are modulated by membrane potential. In recent years, increasing evidence that GPCRs are intrinsically voltage-dependent has accumulated. A recent publication challenged the vie
Externí odkaz:
https://doaj.org/article/0b1669b0f2a948d69a4a90420f7136b8
Autor:
Merav Tauber, Yair Ben-Chaim
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Serotonin (5-HT) plays a central role in various brain functions via the activation of a family of receptors, most of them G protein coupled receptors (GPCRs). 5-HT1A receptor, the most abundant 5-HT receptors, was implicated in many brain dysfunctio
Externí odkaz:
https://doaj.org/article/18be641e465a40b1b962276c66e1b874
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
G-protein coupled receptors are regulated by the membrane potential in vitro. Here, the authors show that muscarinic receptor voltage independence causes a strong behavioural effect of increased odour habituation, showing that these receptors are als
Externí odkaz:
https://doaj.org/article/27bf89b8d8114f41bc59d1b152493aca
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cannabinoids produce their characteristic effects mainly by binding to two types of G-protein coupled receptors (GPCRs), the CB1 and CB2 cannabinoid receptors. The CB1 receptor is the main cannabinoid receptor in the central nervous system, and it pa
Externí odkaz:
https://doaj.org/article/be8d8bc974f940f0aa524b9ff3ee0083
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13988 (2022)
G protein-coupled receptors (GPCRs) are involved in a vast majority of signal transduction processes. Although they span the cell membrane, they have not been considered to be regulated by the membrane potential. Numerous studies over the last two de
Externí odkaz:
https://doaj.org/article/fb74b8cda3284f5eb334350c5580ebe5
Autor:
Noa Raz, Aharon M. Eyal, Dana Berneman Zeitouni, Danielle Hen-Shoval, Elyad M. Davidson, Aviel Danieli, Merav Tauber, Yair Ben-Chaim
Publikováno v:
Biochemical Pharmacology. 212:115548
Autor:
Merav, Tauber, Yair, Ben Chaim
Publikováno v:
The Journal of biological chemistry. 298(6)
G protein-coupled receptors are known to play a key role in many cellular signal transduction processes, including those mediating serotonergic signaling in the nervous system. Several factors have been shown to regulate the activity of these recepto
Autor:
Merav Tauber, Yair Ben Chaim
Publikováno v:
Journal of Biological Chemistry. 298:101978
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
G protein coupled receptors (GPCRs) play a key role in the vast majority of cellular signal transduction processes. Previous experimental evidence has shown that sodium ion (Na+) allosterically modulate several class A GPCRs and theoretical studies s