Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Merari F.R. Ferrari"'
Autor:
Michael F. Almeida, Rodrigo S. Chaves, Carolliny M. Silva, Juliana C.S. Chaves, Karla P. Melo, Merari F.R. Ferrari
Publikováno v:
IBRO Reports, Vol 1, Iss C, Pp 19-31 (2016)
Physical exercise can attenuate the effects of aging on the central nervous system by increasing the expression of neurotrophins such as brain-derived neurotrophic factor (BDNF), which promotes dendritic branching and enhances synaptic machinery, thr
Externí odkaz:
https://doaj.org/article/6d6f7be4705b49698c72ed038e9891fc
Autor:
Rodrigo S. Chaves, Amajad I. Kazi, Carolliny M. Silva, Michael F. Almeida, Raquel S. Lima, Daniel C. Carrettiero, Marilene Demasi, Merari F.R. Ferrari
Publikováno v:
IBRO Reports, Vol 1, Iss C, Pp 32-45 (2016)
Protein aggregation is an important feature of neurodegenerative disorders. In Alzheimer's disease (AD) protein aggregates are composed of hyperphosphorylated Tau and amyloid beta peptide (Aβ). Despite the involvement and identification of the molec
Externí odkaz:
https://doaj.org/article/2c2bd872b6cd46c788c0fa66d67386b3
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Alpha-synuclein aggregation is a hallmark of Parkinson's disease (PD). Mutants A30P and A53T alpha-synuclein are known to exacerbate the toxicity of alpha-synuclein, which includes oxidative stress, mitochondrial and endoplasmic reticulum (ER) dysfun